56 products were found matching "Q13546"!

ATP + a protein = ADP + a phosphoprotein.,Promotes apoptosis and activation of NF-kappa-B. Required for TNFRSF1A mediated activation of NF-kappa-B.,PTM:Autophosphorylated on serine and threonine residues.,PTM:Proteolytically cleaved by caspase-8 during TNF-induced apoptosis. Cleavage abolishes NF-kappa-B activation...

Human RIPK1, also known as RCK and MAP3K19, GenBank Accession No. NM_003804, a.a. 1-327, with N-terminal GST-tag, MW=63 kDa, expressed in a Baculovirus-infected Sf9 cell expression system.

Anti-RIP1 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with RIP1 from other sources has not been determined. Protein function: Serine-threonine kinase which transduces inflammatory and cell-death signals (programmed necrosis) following death receptors...

Protein function: Serine-threonine kinase which transduces inflammatory and cell-death signals (programmed necrosis) following death receptors ligation, activation of pathogen recognition receptors (PRRs), and DNA damage (PubMed:11101870, PubMed:17389591, PubMed:19524512, PubMed:19524513). Upon activation of TNFR1...

Protein function: Serine-threonine kinase which transduces inflammatory and cell-death signals (programmed necrosis) following death receptors ligation, activation of pathogen recognition receptors (PRRs), and DNA damage. Upon activation of TNFR1 by the TNF-alpha family cytokines, TRADD and TRAF2 are recruited to...

Protein function: Serine-threonine kinase which transduces inflammatory and cell-death signals (programmed necrosis) following death receptors ligation, activation of pathogen recognition receptors (PRRs), and DNA damage. Upon activation of TNFR1 by the TNF-alpha family cytokines, TRADD and TRAF2 are recruited to...

Anti-RIPK1 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with RIPK1 from other sources has not been determined. Protein function: Serine-threonine kinase which transduces inflammatory and cell-death signals (programmed necrosis) following death...

0.5mg/ml if reconstituted with 0.2ml sterile DI water. Receptor-interacting serine/threonine-protein kinase 1 (RIPK1), also called RIP, is an enzyme that in humans is encoded by the RIPK1 gene. Members of the TRAF protein family have been implicated in the activation of NF-kappa-B by the TNF superfamily. By yeast...

0.5mg/ml if reconstituted with 0.2ml sterile DI water. RIPK1, also known as RIP or RIP1, is an enzyme that in humans is encoded by the RIPK1 gene. It is mapped to 6p25.2. RIPK1 is a key signaling molecule in the programmed necrosis pathway, which plays important roles in development, tissue damage response, and...

In 1X PBS, pH 7.4, with 0.09% sodium azide. Essential adapter molecule for the activation of NF-kappa-B. Following different upstream signals (binding of inflammatory cytokines, stimulation of pathogen recognition receptors, or DNA damage), particular RIPK1-containing complexes are formed, initiating a limited...

The RIPK1 Kinase Assay Kit is designed to measure RIPK1 kinase activity for screening and profiling applications using ADP-Glo(R) Kinase Assay as a detection reagent.

The RIPK1 Kinase Assay Kit is designed to measure RIPK1 kinase activity for screening and profiling applications using ADP-Glo(R) Kinase Assay as a detection reagent. The RIPK1 Kinase Assay Kit comes in a convenient 384-well format, with enough purified recombinant RIPK1 enzyme, RIPK1 substrate, ATP and kinase assay...