58 products were found matching "Q08499"!

Active human PDE4D3 (GenBank Accession No. U50159), full length, with N-terminal GST tag, MW=102.4 kDa, expressed in a Baculovirus infected Sf9 cell expression system.

The PDE4D Assay Kit is designed for identification of inhibitors of PDE4D2 using fluorescence polarization. Phosphodiesterases (PDEs) play an important role in dynamic regulation of cAMP and cGMP signaling. PDE4D is a regulator of airway smooth-muscle contractility, and has been identified as a potential risk...

Protein function: Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. [The UniProt Consortium]

Protein function: Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. [The UniProt Consortium]

Protein function: Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. [The UniProt Consortium]

Protein function: Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. [The UniProt Consortium]

Protein function: Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. [The UniProt Consortium]

Protein function: Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. [The UniProt Consortium]

Human PDE4D7 (GenBank Accession No. NM_001165899), amino acids 2-748(end) with N-terminal GST-tag, MW=111 kDa, expressed in a Baculovirus infected Sf9 cell expression system. Specific Activity: 4000 pmole/min/µg.

Human PDE4D2 (GenBank Accession No. NM_001197221), amino acids 2-507(end) with N-terminal GST tag, MW=84 kDa, expressed in a Baculovirus infected Sf9 cell expression system. 1 unit is defined as the amount of enzyme that will convert 1 pmole of 3', 5'-cAMP to 5'-AMP per min at 37°C in a reaction buffer. Assay...

The PDE4D3 Assay Kit comes in a convenient 96-well format, with purified PDE4D3 enzyme, fluorescently labeled PDE4D substrate (cAMP), binding agent, and PDE assay buffer for 100 enzyme reactions. The key to the PDE4D3 Assay Kit is the specific binding agent. Using this kit, only two simple steps on a microtiter...

Phosphodiesterases (PDEs) play an important role in the dynamic regulation of cAMP and cGMP signaling. PDE4D has 3',5'-cyclic-AMP phosphodiesterase activity and degrades cAMP. Inhibition of PDE4D activity by its inhibitors leads to an elevated intracellular level of cAMP. The PDE4D gene encodes at least 9 different...