May modulate neuronal adhesion and neurite growth during development by binding to neural cell adhesion molecules (NG-CAM and N-CAM). Chondroitin sulfate proteoglycan, binds to hyaluronic acid Assay Type: Sandwich. Sensitivity: 21.3 pg/mL. Standard: 5000 pg/mL. Detection range: 78.13-5000 pg/mL. Sample type: Tissue...

Neurocan (Neural proteoglycan, also CSPG3) is a secreted, 300-350kD proteoglycan member of the lectican family of molecules. It is expressed by neurons and astrocytes, and has multiple binding partners, including heparin, FGF2, HB-CAM, glypican-1, syndecan-3, and tenascin-C plus -R. Its expression is highest during...

Mouse Neurocan is synthesized as a 1268 amino acid (aa) precursor that contains a 22aa signal sequence and a 1246aa mature chain. The mature chain contains one Iglike Vtype domain (aa37 157), two Link domains (aa159 254 and 258 356), two EGFlike domains (aa960 996 and 998 1034), one Ctype lectinlike domain (aa1036...