The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat CACNa1D. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat CACNa1D. Next,...

Protein function: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The...

Anti-Cav1.3 Antibody was purified by Protein G chromatography. A BLAST analysis was used to suggest cross-reactivity with Cav1.3 from Human, Rat, and Mouse based on 100% homology with the immunizing sequence. No cross-reactivity against Cav1.2. Cross-reactivity with Cav1.3 from other sources has not been determined....

Ion channels are integral membrane proteins that help establish and control the small voltage gradient across the plasma membrane of living cells by allowing the flow of ions down their electrochemical gradient (1). They are present in the membranes that surround all biological , cells because their main function is...