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The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human HSP40. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human HSP40. Next,...

HSP40 and HSP40-like proteins represent a large family of chaperone proteins that are homologous to E. coli DnaJ protein. HSP40 family proteins bind unfolded proteins, prevent their aggregation, and then deliver them to HSP70. Another major function of HSP40 is to stimulate ATPase activity of HSP70, which causes...

0.5mg/ml if reconstituted with 0.2ml sterile DI water. Protein function: Interacts with HSP70 and can stimulate its ATPase activity. Stimulates the association between HSC70 and HIP. Negatively regulates heat shock-induced HSF1 transcriptional activity during the attenuation and recovery phase period of the heat...

The Hsp40(heat shock protein with molecular size of approximately 40 kDa) is one of the mammalian homologues of bacterial DnaJ heat shock protein. Ohtsuka(1993) isolated a cDNA encoding a 40-kD heat-shock protein designated HSPF1. The deduced 340-amino acid HSPF1 protein is 34% identical to E. coli DnaJ and 34% and...

Protein function: Interacts with HSP70 and can stimulate its ATPase activity. Stimulates the association between HSC70 and HIP. [The UniProt Consortium]

Protein function: Interacts with HSP70 and can stimulate its ATPase activity. Stimulates the association between HSC70 and HIP. [The UniProt Consortium]

Protein function: Interacts with HSP70 and can stimulate its ATPase activity. Stimulates the association between HSC70 and HIP. [The UniProt Consortium]

Protein function: Interacts with HSP70 and can stimulate its ATPase activity. Stimulates the association between HSC70 and HIP. Negatively regulates heat shock-induced HSF1 transcriptional activity during the attenuation and recovery phase period of the heat shock response (PubMed:9499401). Stimulates ATP hydrolysis...

Active human Heat Shock Protein 40 (GenBank Accession No. NM_006145), full length with C-terminal His tag, MW = 38.5 kDa, expressed in an E. coli expression system.

Heat shock protein 40 (Hsp40) is an Hsp70 co-chaperone protein that regulates the ATP-dependent binding of Hsp70 (Cay-23002, Cay-22739) to target proteins. There are 44 members of the Hsp40 family in humans, and each Hsp40 contains a unique polypeptide-binding domain that binds and delivers specific target proteins...

Anti-Hsp40 Antibody was prepared from monospecific antiserum by delipidation and defibrination. This polyclonal antibody is specific for human Hsp40 protein. A BLAST analysis was used to suggest cross-reactivity with Hsp40 from Human based on 100% homology with the immunizing sequence. Cross-reactivity with Hsp40...