27 products were found matching "P10997"!

This assay employs the competitive inhibition enzyme immunoassay technique. The microtiter plate provided in this kit has been pre-coated with Human IAPP protein. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human IAPP. Next, Avidin...

Amylin is a 37-residue peptide hormone secreted from pancreatic beta-cells that reduces food intake, decreases glucagon secretion, slows gastric emptying, and increases satiety. It binds to amylin receptors with IC50 values of 2 and 0.2 nM for porcine and guinea pig nucleus accumbens membrane preparations,...

The kit is a competitive enzyme immunoassay for in vitro quantitative measurement of IAPP in serum, plasma and other biological fluids. Detection Range: 62.5--4000pg/mL. Sensitivity: 37.5pg/mL. Protein function: Selectively inhibits insulin-stimulated glucose utilization and glycogen deposition in muscle, while not...

Amylin is a peptide hormone secreted from pancreatic beta-cells that reduces food intake, decreases glucagon secretion, slows gastric emptying, and increases satiety. Native amylin is a cleavage product of proamylin that is processed and amidated at the C-terminus, a modification that is required for its biological...

Islet, or insulinoma, amyloid polypeptide is commonly found in pancreatic islets of patients suffering diabetes mellitus type II, or harboring an insulinoma. While the association of amylin with the development of type II diabetes has been known for some time, a direct causative role for amylin has been harder to...

Pramlintide is a non-amyloidogenic analog of the antidiabetic peptide hormone amylin (Cay-24274, Cay-24275) that contains proline residues substituted at positions 25, 28, and 29. It stimulates cAMP production in HEK293 cells expressing human amylin receptor 1a (AMY1a), AMY2a, and AMY3a (EC50s = 0.35, 22.9, and 0.89...

ELISA Type: Competitive. Sensitivity: 37.5pg/mL. Range: 62.5--4000pg/mL. Protein function: Selectively inhibits insulin-stimulated glucose utilization and glycogen deposition in muscle, while not affecting adipocyte glucose metabolism. [The UniProt Consortium]

Protein function: Selectively inhibits insulin-stimulated glucose utilization and glycogen deposition in muscle, while not affecting adipocyte glucose metabolism. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse:...

The kit is a competitive enzyme immunoassay for in vitro quantitative measurement of IAPP in serum, plasma and other biological fluids. Detection Range: 62.5--4000pg/mL. Sensitivity: 37.5pg/mL. Protein function: Selectively inhibits insulin-stimulated glucose utilization and glycogen deposition in muscle, while not...

islet amyloid polypeptide(IAPP) Homo sapiens This gene encodes a member of the calcitonin family of peptide hormones. This hormone is released from pancreatic beta cells following food intake to regulate blood glucose levels and act as a satiation signal. Human patients with type 1 and advanced type 2 diabetes...