The n-Myc protooncogene is a member of the Myc family of transcription factors which includes c-Myc and L-Myc. Myc transcription factors are required for normal development and play a role in cell-cycle progression, transformation, cell size, and apoptosis. Myc factors heterodimerize with the transcription factor...

Primers are provided as a 40 µl solution containing both primers at a final concentration of 50 µM in 10 mM Tris-HCl (pH 7.5), 0.1 mM EDTA. Dilute with water as needed prior to use. This amount is sufficient for 1000 x 20µl PCR reactions assuming a final primer concentration of 0.1 µM. Add cDNA template....

N-Myc is a member of the Myc family of proteins which include c-Myc, N-Myc, and L-Myc. Myc family members are transactivating DNA binding proteins with oncogenic potential. Transactivation by Myc requires dimerization with other basic helix-loop-helix transcription factors. N-myc dimerizes with the MAX transcription...