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The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human PSCA. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human PSCA. Next,...

Protein function: May be involved in the regulation of cell proliferation. Has a cell-proliferation inhibition activity in vitro. [The UniProt Consortium]

PSCA (Prostate Stem Cell antigen) is a cell surface antigen, which is overexpressed in ~40% of primary prostate cancers and in as many as 100% of metastatic ones. PSCA is also overexpressed in a majority of transitional cell and pancreatic carcinomas. Antibody directed against PSCA inhibits tumorigenesis, slows...

Protein function: May be involved in the regulation of cell proliferation. Has a cell-proliferation inhibition activity in vitro. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 59% and to rat: 60%

Recombinant Human PSCA Protein is expressed from HEK293 with hFc tag at the N-Terminus.It contains Leu12-Ser86. Gastric cancer is a deadly malignancy and is a prognostically unfavorable entity with restricted therapeutic strategies available. Prostate stem cell antigen (PSCA) is a glycosylphosphatidylinositol...

This gene encodes a glycosylphosphatidylinositol-anchored cell membrane glycoprotein. In addition to being highly expressed in the prostate it is also expressed in the bladder, placenta, colon, kidney, and stomach. This gene is up-regulated in a large proportion of prostate cancers and is also detected in cancers of...

PSCA (Prostate Stem Cell antigen) is a cell surface antigen which is overexpressed in ~40% of primary prostate cancers and in nearly 100% of metastatic ones. PSCA is also overexpressed in a majority of transitional cell and pancreatic carcinomas. Antibody directed against PSCA inhibits tumorigenesis, slows tumor...

PSCA is a glycosylphosphatidylinositol-anchored cell membrane glycoprotein. In addition to being highly expressed in the prostate it is also expressed in the bladder, placenta, colon, kidney, and stomach. It is up-regulated in a large proportion of prostate cancers and is also detected in cancers of the bladder and...

Prostate Stem Cell Antigen (PSCA) BioAssayT ELISA Kit (Human) is a sandwich enzyme immunoassay for in vitro quantitative measurement of PSCA in human tissue homogenates and other biological fluids. Detection Range: 0.156-10ng/ml, Sensitivity: 0.055ng/ml, Storage and Stability: Desiccation recommended. The Standard,...

PSCA (prostate stem cell antigen) is a glycosylphosphatidylinositol (GPI)­anchored cell surface protein of the Thy­1/Ly­6 family. PSCA is expressed in differentiating cells and epithelial cells of the prostate, bladder, kidney, skin, esophagus, stomach and placenta. It may be up­ or down­regulated in cancer and may...