33 products were found matching "K23561"!

Leucettine L41 is an inhibitor of dual-specificity tyrosine phosphorylation-regulated kinase 1A (DYRK1A), DYRK2, CDC-like kinase 1 (CLK1), and CLK3 (IC50s = 0.04, 0.035, 0.015, and 4.5 µM, respectively). It also inhibits GSK3alpha/beta and Pim1 with IC50 values of 0.41 and 4.1 µM, respectively. It inhibits...

Protein function: Dual specificity kinase acting on both serine/threonine and tyrosine-containing substrates. Phosphorylates serine- and arginine- rich (SR) proteins of the spliceosomal complex and may be a constituent of a network of regulatory mechanisms that enable SR proteins to control RNA splicing....

Protein function: Dual specificity kinase acting on both serine/threonine and tyrosine-containing substrates. Phosphorylates serine- and arginine- rich (SR) proteins of the spliceosomal complex and may be a constituent of a network of regulatory mechanisms that enable SR proteins to control RNA splicing....

The Chemi-Verse(TM) CLK1 Kinase Assay Kit is designed to measure CLK1 (CDC2-like kinase 1) kinase activity for screening and profiling applications using ADP-Glo(TM) as a detection reagent. The assay kit comes in a convenient 96-well format, with enough purified recombinant CLK1 kinase (amino acids 129-end), kinase...

RS repeat peptide is a serine/arginine-rich peptide substrate for CDC-like kinase 1 (Clk1). It has been used to identify inhibitors of Clk1 with anticancer activity.Formal Name:...

Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...

Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...

Host Species: Rabbit. Isotype: IgG. Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by...

Host Species: Rabbit. Isotype: IgG. Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by...

MU1210 is an inhibitor of CDC-like kinase 1 (Clk1), Clk2, and Clk4 (IC50s = 8, 20, and 12 nM, respectively). It is selective for these kinases over Clk3 (IC50 = >3,000 nM), as well as dual-specificity tyrosine phosphorylation-regulated kinase 1A (DYRK1A), DYRK1B, DYRK2, homeodomain-interacting protein kinase 1...

T3-CLK is a pan inhibitor of CDC-like kinases (Clks, IC50s = 0.67, 15, and 110 nM for Clk1, Clk2, and Clk3, respectively). It is selective for Clk1-3 over dual-specificity tyrosine phosphorylation-regulated kinase 1A (DYRK1A) and DYRK1B (IC50s = 260 and 230 nM, respectively), as well as 62 kinases in a panel at...

Protein Function: Dual specificity kinase acting on both serine/threonine and tyrosine-containing substrates. Phosphorylates serine- and arginine-rich (SR) proteins of the spliceosomal complex and may be a constituent of a network of regulatory mechanisms that enable SR proteins to control RNA splicing....