10 products were found matching "K23129"!

Hepatitis B virus (HBV) core protein, the building block of the HBV capsid, plays multiple roles in viral replication, and is an attractive target for development of antiviral agents with a new mechanism of action.

Protein function: Self assembles to form an icosahedral capsid. Most capsid appear to be large particles with an icosahedral symmetry of T=4 and consist of 240 copies of capsid protein, though a fraction forms smaller T=3 particles consisting of 180 capsid proteins. Entering capsid are transported along microtubules...

Description: Vebicorvir (ABI-H0731), a first-generation hepatitis B virus (HBV) core protein inhibitor, has demonstrated effective antiviral activity. Target: HBV. Smiles: FC(F)(F)c1ncc(CNC(=O)c2ccc3c(NC(=O)c4ccccc4S3(=O)=O)c2)s1. References: Huang Q, Cai D, Yan R, Li L, Zong Y, Guo L, Mercier A, Zhou Y, Tang A,...

Description: Bersacapavir is a novel Hepatitis B Virus capid assembly modulator with a dual mode of action in vitro[1]. Target: Others. Smiles: C[C@H](NS(=O)(=O)c1cc(C(=O)Nc2ccc(F)c(c2)C#N)n(C)c1)C(F)(F)F

Description: Hepatitis B virus (HBV) capsid assembly is a critical step in the propagation of the virus and is mediated by the core protein. The first cytoplasmic step in the formation of an infectious HBV virion is the formation of a capsid containing pregenomic RNA (pgRNA) and the viral polymerase (Pol). HBV...

Description: Linvencorvir is a hepatitis B virus (HBV) core protein variant modifier used to treat chronic HBV infection. Target: HBV, Antibiotic. Smiles: C(OCC)(=O)C=1[C@@H](NC(=NC1CN2C[C@@]3(N(CC2)C(=O)N(CC(C(O)=O)(C)C)C3)[H])C4=NC=CS4)C5=C(C)C(F)=CC=C5. References: Zhang W, et al. Discovery of Linvencorvir...

HBcAg Monoclonal Antibody from Assay Genie is a high quality antibody for research use only. Protein Function: Self assembles to form an icosahedral capsid. Most capsids appear to be large particles with an icosahedral symmetry of T=4 and consist of 240 copies of capsid protein, though a fraction forms smaller T=3...

Reacts strongly with human HBV positive serum. Source: Recombinant protein corresponding to aa1-183 of HBV core, fused to 6-His, expressed in E. coli. Molecular Weight: ~25, 28kD, Applications: Suitable for use in ELISA, Western Blot, Lateral flow. Other applications not tested. Recommended Dilution: Optimal...

Protein Construction: A DNA sequence encoding the Hepatitis B Virus (HBV)(ayw/France/Tiollais/1979) Capsid protein (P03146-1) (Met1-Val149) was expressed with a polyhistidine tag at the C-terminus. Sequence: Met1-Val149. Fusion tag: C-His Endotoxin: Please contact us for more information. Protein function: Hepatitis...

Protein function: Self assembles to form an icosahedral capsid. Most capsids appear to be large particles with an icosahedral symmetry of T=4 and consist of 240 copies of capsid protein, though a fraction forms smaller T=3 particles consisting of 180 capsid proteins. Entering capsids are transported along...