7 products were found matching "K22274"!
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Voxilaprevir
Item number: Cay33974-1
Voxilaprevir is a pan-genotypic hepatitis C virus (HCV) non-structural 3/4A (NS3/4A) serine protease inhibitor. It inhibits replication of wild-type HCV genotypes 1a, 1b, 2a, 2b, 3a, 4a, 5a, and 6a (EC50s = 1.9-6.6 nM in replicon assays). Voxilaprevir also inhibits replication of mutant HCV genotypes containing NS3...
| Keywords: | GS-9857,... |
| Application: | Pan-genotypic HCV NS3/4A protease inhibitor |
| CAS | 1535212-07-7 |
| MW: | 868.9 D |
From 163.00€
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Boceprevir
Item number: ABE-15-4001-5
Molecular Formula: C27H45N5O5, Molecular Weight: 519.7 Boceprevir is a protease inhibitor that covalently, yet reversibly, binds (Ki = 14 nM) to the catalytic site (Ser139) of hepatitis C virus (HCV) nonstructural protein 3/4A (NS3/4A), a serine protease that is essential for viral replication.It was shown to...
| Application: | Antiviral, HCV NS3/4A protease inhibitor |
| MW: | 519.7 D |
From 324.00€
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Grazoprevir
Item number: ABE-15-4003-5
Molecular Formula: C38H50N6O9S Molecular Weight: 766.9 Grazoprevir is a pan-genotypic protease inhibitor that binds to hepatitis C virus (HCV) non-structural protein 3/4A (NS3/4A), a serine protease essential for viral replication.Grazoprevir has potent in vitro activity against major HCV genotypes (Kis...
| Application: | Antiviral, HCV NS3/4A protease inhibitor |
| MW: | 766.9 D |
From 222.00€
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Danoprevir
Item number: ABE-15-4004-5
Molecular Formula: C35H46FN5O9S Molecular Weight: 731.8 Danoprevir is an orally bioavailable inhibitor of hepatitis C virus (HCV) nonstructural protein 3/4A (NS3/4A, IC50 = 1 nM), a serine protease essential for HCV replication.It is selective for NS3/4A over a panel of 53 proteases at a concentration of 10 μM....
| Application: | Antiviral, HCV NS3/4A protease inhibitor |
| MW: | 731.8 D |
From 222.00€
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Simeprevir (sodium salt)
Item number: ABE-15-4005-5
Molecular Formula: C38H47N5O7S2 . XNa Molecular Weight: 749.9 Simeprevir is an orally bioavailable and potent inhibitor of the hepatitis C virus (HCV) nonstructural protein 3/4A (NS3/4A) protease (Ki = 0.36 nM), a serine protease essential for HCV replication. It inhibits HCV viral replication with an EC50 value of...
| Application: | Antiviral, HCV NS3/4A protease inhibitor |
| MW: | 749.9 D |
From 170.00€
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Paritaprevir
Item number: ABE-15-4006-5
Molecular Formula: C40H43N7O7S Molecular Weight: 765.9 Paritaprevir is an orally bioavailable, direct-acting inhibitor of the hepatitis C virus (HCV) non-structural 3/4A (NS3/4A) serine protease.It inhibits HCV replication in stable Huh7-derived replicon cell lines infected with subgenomic genotypes 1a, 1b, 2a, 3a,...
| Application: | Antiviral, HCV NS3/4A protease inhibitor |
| MW: | 765.9 D |
From 443.00€
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Glecaprevir
Item number: ABE-15-4007-5
Molecular Formula: C38H46F4N6O9S Molecular Weight: 838.9 Glecaprevir is an orally bioavailable and direct-acting inhibitor of the hepatitis C virus (HCV) non-structural 3/4A (NS3/4A) serine protease.It inhibits NS3/4A from HCV genotypes 1a, 1b, 2a, 2b, 3a, 4a, 5a, and 6a (IC50s = 4.6, 8.9, 3.5, 3.8, 7.9, 6.1, 8.1,...
| Application: | Antiviral, HCV NS3/4A protease inhibitor |
| MW: | 838.9 D |
From 153.00€
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