14 products were found matching "K21955"!

Protein function: Lysosomal modulator of autophagy that plays a central role in p53/TP53-mediated apoptosis. Not involved in p73/TP73- mediated autophagy. [The UniProt Consortium]

Anti-DRAM Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with DRAM from other sources has not been determined. Protein function: Lysosomal modulator of autophagy that plays a central role in p53/TP53-mediated apoptosis. Not involved in p73/TP73- mediated...

0.5 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide. Autophagy is the mechanism by which lysosomes degrade unneeded or dysfunctional cellular components. p53 is a tumor suppressor protein that modulates autophagy and apoptosis. DRAM, or damage regulated autophagy modulator, is a lysosomal protein and...

DRAM (DNA-damage regulated autophagy modulator 1) with a molecular weight of 26 kDa is a lysosomal modulator of autophagy that plays a central role in p53/TP53-mediated apoptosis. It belongs to DRAM/TMEM150 family. This gene is regulated as part of the p53 tumor suppressor pathway. DRAM has a pseudogene on...

Protein function: Lysosomal modulator of autophagy that plays a central role in p53/TP53-mediated apoptosis. Not involved in p73/TP73- mediated autophagy. [The UniProt Consortium]

DRAM (DNA-damage regulated autophagy modulator 1) with a molecular weight of 26 kDa is a lysosomal modulator of autophagy that plays a central role in p53/TP53-mediated apoptosis. It belongs to DRAM/TMEM150 family. This gene is regulated as part of the p53 tumor suppressor pathway. DRAM has a pseudogene on...

WB 1:200 - 1:2000. Protein function: Lysosomal modulator of autophagy that plays a central role in p53/TP53-mediated apoptosis. Not involved in p73/TP73- mediated autophagy. [The UniProt Consortium]

This gene is regulated as part of the p53 tumor suppressor pathway. The gene encodes a lysosomal membrane protein that is required for the induction of autophagy by the pathway. Decreased transcriptional expression of this gene is associated with various tumors. This gene has a pseudogene on chromosome 4. Protein...

This gene is regulated as part of the p53 tumor suppressor pathway. The gene encodes a lysosomal membrane protein that is required for the induction of autophagy by the pathway. Decreased transcriptional expression of this gene is associated with various tumors. This gene has a pseudogene on chromosome 4. [provided...

DRAM is regulated as part of the p53 tumor suppressor pathway. It is a lysosomal membrane protein that is required for the induction of autophagy by the pathway. Decreased transcriptional expression of this protein is associated with various tumors. Applications: Suitable for use in Immunohistochemistry, ELISA,...

Damage-regulated autophagy modulator (DRAM) is a p53 target gene encoding a lysosomal protein that induces autophagy (1), a process that degrades cytosolic proteins and organelles (reviewed in 2). It has been suggested that activation of DRAM by p53 is simultaneous to the activation by p53 of one or more...