54 products were found matching "K21357"!
No results were found for the filter!
ULK-101
Item number: Cay40403-1
ULK-101 is an inhibitor of unc-51-like autophagy activating kinase 1 (ULK1) and ULK2 (IC50s = 8.3 and 30 nM, respectively). It is selective for ULK1 and ULK2 over a panel of 325 additional kinases at 10 µM but does inhibit serine/threonine kinase 17a (STK17A), also known as DRAK1, and MAP kinase-interacting...
| Keywords: | N-[(1S)-1-cyclopropyl-2,2,2-trifluoroethyl]-4-[6-(4-fluorophenyl)pyrazolo[1,5-a]pyrimidin-3-yl]-2-thiophenecarboxamide |
| Application: | ULK1 / ULK2 inhibitor |
| CAS | 2443816-45-1 |
| MW: | 460.4 D |
From 38.00€
*
Anti-phospho-ULk1 (Ser757)
Item number: G-CABP0736.100
WB 1:500 - 1:2000. Protein function: Serine/threonine-protein kinase involved in autophagy in response to starvation. Acts upstream of phosphatidylinositol 3- kinase PIK3C3 to regulate the formation of autophagophores, the precursors of autophagosomes. Part of regulatory feedback loops in autophagy: acts both as a...
| Keywords: | Anti-phospho-ATG1, Anti-phospho-ULK1, Anti-phospho-hATG1, Anti-phospho-KIAA0722, EC=2.7.11.1, Anti-phospho-Unc-51-like... |
| Application: | WB |
| Host: | Rabbit |
| Species reactivity: | human |
From 352.00€
*
ULK, active human recombinant protein
Item number: BPS-40099
Human ULK1 (GenBank Accession No. NM_003565), amino-acids 2-end with N-terminal DDDDK tag (FLAG), MW = 113 kDa, expressed in FreeStyle 293-F cells Application: Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
| Keywords: | ATG1, hATG1, Unc-51-like kinase 1, Autophagy-related protein 1 homolog, Serine/threonine-protein kinase ULK1, |
| Application: | Enzyme kinetics, inhibitor screening |
| MW: | 113 kD |
599.00€
*
Anti-UNG1
Item number: 600-401-FV0
Anti-UNG1 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with UNG1 from other sources has not been determined. Protein function: Serine/threonine-protein kinase involved in autophagy in response to starvation. Acts upstream of phosphatidylinositol 3-...
| Keywords: | Anti-ULK1, Anti-ATG1, Anti-hATG1, Anti-KIAA0722, EC=2.7.11.1, Anti-Unc-51-like kinase 1, Anti-Autophagy-related protein 1... |
| Application: | ELISA, IHC, IFM, WB |
| Host: | Rabbit |
| Species reactivity: | human, mouse, rat |
684.00€
*
LYN-1604
Item number: Cay24007-1
LYN-1604 is an activator of unc-51-like kinase 1 (ULK1, EC50 = 18.94 nM). It increases Beclin 1, LC3-II, and total LC3 protein levels and reduces levels of p62 in human MDA-MB-231 triple-negative breast cancer (TNBC) cells in a concentration-dependent manner, indicating an increase in autophagy. It also increases...
| Keywords: | 2-[bis(2-methylpropyl)amino]-1-[4-[2-(2,4-dichlorophenyl)-2-(2-naphthalenylmethoxy)ethyl]-1-piperazinyl]-ethanone |
| Application: | ULK1 activator |
| CAS | 2088939-99-3 |
| MW: | 584.6 D |
From 109.00€
*
Anti-phospho-ULK1 (Ser556)
Item number: NSJ-F48759-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. Involved in autophagy. Required for autophagosome formation (By similarity). Target of the TOR kinase signaling pathway that regulates autophagy through the control of phosphorylation status of ATG13/KIAA0652 and ULK1, and the regulation of the ATG13-ULK1-RB1CC1 complex...
| Keywords: | Anti-phospho-ATG1, Anti-phospho-ULK1, Anti-phospho-hATG1, Anti-phospho-KIAA0722, EC=2.7.11.1, Anti-phospho-Unc-51-like... |
| Application: | IF, Dot Blot, ELISA |
| Host: | Rabbit |
| Species reactivity: | human |
From 326.00€
*
Anti-ULK1
Item number: NSJ-F47190-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. ULK1 is a target of the TOR kinase signaling pathway that regulates autophagy through the control of phosphorylation status of ATG13/KIAA0652 and ULK1, and the regulation of the ATG13-ULK1-RB1CC1 complex (By similarity). [UniProt] Protein function: Serine/threonine-protein...
| Keywords: | Anti-ATG1, Anti-ULK1, Anti-hATG1, Anti-KIAA0722, EC=2.7.11.1, Anti-Unc-51-like kinase 1, Anti-Autophagy-related protein 1... |
| Application: | WB, ELISA |
| Host: | Rabbit |
| Species reactivity: | human |
From 326.00€
*
Anti-phospho-ULK1 (Ser467)
Item number: NSJ-F48812-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. ULK1 is involved in autophagy. Required for autophagosome formation (By similarity). Target of the TOR kinase signaling pathway that regulates autophagy through the control of phosphorylation status of ATG13/KIAA0652 and ULK1, and the regulation of the ATG13-ULK1-RB1CC1...
| Keywords: | Anti-phospho-ATG1, Anti-phospho-ULK1, Anti-phospho-hATG1, Anti-phospho-KIAA0722, EC=2.7.11.1, Anti-phospho-Unc-51-like... |
| Application: | Dot Blot, ELISA |
| Host: | Rabbit |
| Species reactivity: | human |
From 326.00€
*
Anti-phospho-ULK1 (Ser317)
Item number: NSJ-F48758-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. Involved in autophagy. Required for autophagosome formation (By similarity). Target of the TOR kinase signaling pathway that regulates autophagy through the control of phosphorylation status of ATG13/KIAA0652 and ULK1, and the regulation of the ATG13-ULK1-RB1CC1 complex...
| Keywords: | Anti-phospho-ATG1, Anti-phospho-ULK1, Anti-phospho-hATG1, Anti-phospho-KIAA0722, EC=2.7.11.1, Anti-phospho-Unc-51-like... |
| Application: | Dot Blot, ELISA |
| Host: | Rabbit |
| Species reactivity: | human |
From 326.00€
*
Anti-ULK1
Item number: NSJ-F51530-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. ULK1/ATG1 is involved in autophagy. It is required for autophagosome formation. Target of the TOR kinase signaling pathway that regulates autophagy through the control of phosphorylation status of ATG13 and ULK1, and the regulation of the ATG13-ULK1-RB1CC1 complex....
| Keywords: | Anti-ATG1, Anti-ULK1, Anti-hATG1, Anti-KIAA0722, EC=2.7.11.1, Anti-Unc-51-like kinase 1, Anti-Autophagy-related protein 1... |
| Application: | WB, IHC, FC, ELISA |
| Host: | Rabbit |
| Species reactivity: | human, mouse |
From 326.00€
*
Anti-ULK1
Item number: NSJ-F47201-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. ULK1 is involved in autophagy. Required for autophagosome formation (By similarity). Target of the TOR kinase signaling pathway that regulates autophagy through the control of phosphorylation status of ATG13/KIAA0652 and ULK1, and the regulation of the ATG13-ULK1-RB1CC1...
| Keywords: | Anti-ATG1, Anti-ULK1, Anti-hATG1, Anti-KIAA0722, EC=2.7.11.1, Anti-Unc-51-like kinase 1, Anti-Autophagy-related protein 1... |
| Application: | WB, ELISA |
| Host: | Rabbit |
| Species reactivity: | human |
From 326.00€
*
Human ULK1 (Unc-51 Like Kinase 1) ELISA Kit
Item number: G-HUFI03341.96
ELISA Type: Sandwich. Sensitivity: 9.375pg/ml. Range: 15.625-1000pg/ml. Protein function: Serine/threonine-protein kinase involved in autophagy in response to starvation. Acts upstream of phosphatidylinositol 3-kinase PIK3C3 to regulate the formation of autophagophores, the precursors of autophagosomes. Part of...
| Keywords: | ATG1, ULK1, hATG1, KIAA0722, EC=2.7.11.1, Unc-51-like kinase 1, Autophagy-related protein 1 homolog,... |
| Application: | Sandwich ELISA |
| Species reactivity: | human |
641.00€
*