- Search results for K21289
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43 products were found matching "K21289"!
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Item number: ELK-ES6590.100
Phosphoinositide 3-kinases (PI3Ks) phosphorylate inositol lipids and are involved in the immune response. The protein encoded by this gene is a class I catalytic subunit of PI3K. Like other class I catalytic subunits (p110-alpha p110-beta, and p110-delta), the encoded protein binds a p85 regulatory subunit to form...
Keywords: | Anti-PIK3CG, Anti-p110gamma, Anti-PI3Kgamma, Anti-p120-PI3K, Anti-PI3K-gamma, Anti-PI3-kinase subunit gamma,... |
Application: | WB, IHC, IF, ELISA |
Host: | Rabbit |
Species reactivity: | human, rat, mouse, |
From 169.00€
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Item number: BPS-82104
The Chemi-Verse(TM) PI3 Kinase (p120gamma) Kinase Assay Kit is designed to measure PI3 (phosphoinositide 3) kinase (p120gamma) kinase activity for screening and profiling applications using ADP-Glo(TM) as a detection reagent. The assay kit comes in a convenient 96-well format, with enough purified recombinant PI3...
Keywords: | PIK3CG, p110gamma, p120-PI3K, PI3Kgamma, PI3K-gamma, PI3-kinase subunit gamma, PtdIns-3-kinase subunit gamma,... |
Application: | Enzyme kinetics, small molecule inhibitor screening, drug discovery, HTS |
Species reactivity: | human |
891.00€
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Item number: Cay26416-1
IPI-549 is an inhibitor of PI3Kgamma (IC50s = 16, 3,200, 3,500, and >8,400 nM for PI3Kgamma, PI3Kalpha, PI3Kbeta, and PI3Kdelta, respectively). It is greater than 100-fold selective for PI3Kgamma over a panel of 468 mutant and nonmutant protein and lipid kinases, including Class II PI3K isoforms, and a panel of 80 G...
Keywords: | 2-amino-N-[(1S)-1-[1,2-dihydro-8-[2-(1-methyl-1H-pyrazol-4-yl)ethynyl]-1-oxo-2-phenyl-3-isoquinolinyl]ethyl]-pyrazolo[1,5-... |
Application: | PI3Kgamma inhibitor |
CAS | 1693758-51-8 |
MW: | 528.6 D |
From 48.00€
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Item number: BPS-40625
Active human p120gamma ( GenBank Accession No. AF327656), full length with N-terminal His tag, MW=131 kDa, expressed in a Baculovirus infected Sf9 cell expression system.
Keywords: | PIK3CG, p110gamma, p120-PI3K, PI3Kgamma, PI3K-gamma, PI3-kinase subunit gamma, PtdIns-3-kinase subunit gamma,... |
Application: | Enzyme kinetics, inhibitor screening |
MW: | 131 kD |
642.00€
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Item number: E-AB-13516.120
This gene encodes a protein that belongs to the pi3/pi4-kinase family of proteins. The gene product is an enzyme that phosphorylates phosphoinositides on the 3-hydroxyl group of the inositol ring. It is an important modulator of extracellular signals, including those elicited by E-cadherin-mediated cell-cell...
Keywords: | Anti-PIK3CG, Anti-PI3Kgamma, Anti-p110gamma, Anti-p120-PI3K, Anti-PI3K-gamma, EC=2.7.11.1, EC=2.7.1.153, Anti-PI3-kinase... |
Application: | IHC, ELISA |
Host: | Rabbit |
Species reactivity: | human, mouse |
From 71.00€
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Item number: E-AB-16713.120
This gene encodes a protein that belongs to the pi3/pi4-kinase family of proteins. The gene product is an enzyme that phosphorylates phosphoinositides on the 3-hydroxyl group of the inositol ring. It is an important modulator of extracellular signals, including those elicited by E-cadherin-mediated cell-cell...
Keywords: | Anti-PIK3CG, Anti-PI3Kgamma, Anti-p110gamma, Anti-p120-PI3K, Anti-PI3K-gamma, EC=2.7.11.1, EC=2.7.1.153, Anti-PI3-kinase... |
Application: | IHC, ELISA |
Host: | Rabbit |
Species reactivity: | human, mouse |
From 71.00€
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Item number: E-AB-60055.120
Phosphoinositide 3-kinases (PI3Ks) phosphorylate inositol lipids and are involved in the immune response. The protein encoded by this gene is a class I catalytic subunit of PI3K. Like other class I catalytic subunits (p110-alpha p110-beta, and p110-delta), the encoded protein binds a p85 regulatory subunit to form...
Keywords: | Anti-PIK3CG, Anti-p110gamma, Anti-PI3Kgamma, Anti-p120-PI3K, Anti-PI3K-gamma, EC=2.7.11.1, EC=2.7.1.153, Anti-PI3-kinase... |
Application: | WB |
Host: | Rabbit |
Species reactivity: | human, mouse, rat |
From 198.00€
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Item number: Cay26410-50
CH5132799 is an inhibitor of class I PI3K isoforms (IC50s = 14, 120, 500, and 36 nM for PI3Kalpha, PI3Kbeta, PI3Kdelta, and PI3Kgamma, respectively). It is selective for these PI3K isoforms over PI3KC2alpha and PI3KC2beta, which are class II PI3Ks, Vps34, a class III PI3K, and mTOR (IC50s = 5,300, >10,000, >10,000,...
Keywords: | 5-[6,7-dihydro-7-(methylsulfonyl)-2-(4-morpholinyl)-5H-pyrrolo[2,3-d]pyrimidin-4-yl]-2-pyrimidinamine |
Application: | PI3K alpha / beta / delta / gamma inhibitor |
CAS | 1007207-67-1 |
MW: | 377.4 D |
From 266.00€
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Item number: BPS-79803
The PI3Kgamma (p110gamma/PIK3R5) Assay Kit is designed to measure PI3Kgamma activity for screening and profiling applications, using ADP-Glo(R) Kinase Assay as a detection reagent.
Keywords: | PIK3CG, p110gammaPIK3R5, phosphoinositide-3-kinase regulatory subunit 5, FOAP2, |
Application: | Enzyme kinetics, drug discovery, HTS |
Species reactivity: | human |
789.00€
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Item number: Cay27664-5
PKI-402 is a dual inhibitor of PI3K and mammalian target of rapamycin (mTOR, IC50s = 1.4, 9.2, and 1.7 nM for PI3Kalpha, PI3Kgamma, and mTOR, respectively). It reduces proliferation of MDA-MB-361 and PC3 cancer cells (IC50s = 8 and 21 nM, respectively) and inhibits phosphorylation of Akt in MDA-MB-361 cells (IC50 =...
Keywords: | N-[4-[3-ethyl-7-(4-morpholinyl)-3H-1,2,3-triazolo[4,5-d]pyrimidin-5-yl]phenyl]-N'-[4-[(4-methyl-1-piperazinyl)carbonyl]phe... |
Application: | PI3K, mTOR dual inhibitor |
CAS | 1173204-81-3 |
MW: | 570.6 D |
From 77.00€
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Item number: Cay30323-10
Voxtalisib is a dual inhibitor of PI3K and mammalian target of rapamycin complex (mTORC, IC50s = 39, 110, 43, 9, 160, and 910 nM for PI3Kalpha, PI3Kbeta, PI3Kdelta, PI3Kgamma, mTORC1, and mTORC2, respectively). It is selective for these kinases over vacuolar protein sorting 34 (VPS34, IC50 = 9,100 nM) and a panel of...
Keywords: | SAR245409, XL765, 2-amino-8-ethyl-4-methyl-6-(1H-pyrazol-3-yl)-pyrido[2,3-d]pyrimidin-7(8H)-one |
Application: | mTORC / PI3K dual inhibitor |
CAS | 934493-76-2 |
MW: | 270.3 D |
From 158.00€
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Item number: E-AB-67781.120
Phosphoinositide 3-kinases (PI3Ks) phosphorylate inositol lipids and are involved in the immune response. The protein encoded by this gene is a class I catalytic subunit of PI3K. Like other class I catalytic subunits (p110-alpha p110-beta, and p110-delta), the encoded protein binds a p85 regulatory subunit to form...
Keywords: | Anti-PIK3CG, Anti-PI3Kgamma, Anti-p120-PI3K, Anti-p110gamma, Anti-PI3K-gamma, EC=2.7.11.1, EC=2.7.1.153, Anti-PI3-kinase... |
Application: | IHC |
Host: | Rabbit |
Species reactivity: | human |
From 198.00€
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