- Search results for K20735
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18 products were found matching "K20735"!
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Item number: Cay21753-10
MK-886 is a potent, selective inhibitor of 5-lipoxygenase-activating protein (FLAP) that prevents 5-lipoxygenase activation in vivo and inhibits leukotriene biosynthesis in leukocytes with an IC50 of 2.5 nM. In human whole blood, leukotriene biosynthesis is inhibited by MK-886 with an IC50 of 1.1 µM.Formal Name:...
Keywords: | L-663,536,... |
Application: | FLAP inhibitor |
CAS | 118414-82-7 |
MW: | 472.1 D |
From 46.00€
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Item number: Cay28103-5
Diflapolin is a dual inhibitor of 5-lipoxygenase-activating protein (FLAP) and soluble epoxide hydrolase (sEH). It inhibits formation of the 5-lipoxygenase (5-LO) products leukotriene B4 (LTB4, Cay-20110) and 5-HpETE (Cay-44230) in isolated human monocytes and neutrophils (IC50s = 30 and 170 nM, respectively) and...
Keywords: | N-[4-(2-benzothiazolylmethoxy)-2-methylphenyl]-N'-(3,4-dichlorophenyl)-urea |
Application: | 5-lipoxygenase-activating protein (FLAP) inhibitor, Soluble epoxide hydrolase (sEH) inhibitor |
CAS | 724453-98-9 |
MW: | 458.4 D |
From 64.00€
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Item number: ARG63583.100
Protein function: Required for leukotriene biosynthesis by ALOX5 (5- lipoxygenase). Anchors ALOX5 to the membrane. Binds arachidonic acid, and could play an essential role in the transfer of arachidonic acid to ALOX5. Binds to MK-886, a compound that blocks the biosynthesis of leukotrienes. [The UniProt Consortium]
Keywords: | Anti-FLAP, Anti-ALOX5AP, Anti-MK-886-binding protein, Anti-Arachidonate 5-lipoxygenase-activating protein |
Application: | ELISA, WB |
Host: | Goat |
Species reactivity: | human |
784.00€
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Item number: ARG64056.100
Protein function: Required for leukotriene biosynthesis by ALOX5 (5- lipoxygenase). Anchors ALOX5 to the membrane. Binds arachidonic acid, and could play an essential role in the transfer of arachidonic acid to ALOX5. Binds to MK-886, a compound that blocks the biosynthesis of leukotrienes. [The UniProt Consortium]
Keywords: | Anti-FLAP, Anti-ALOX5AP, Anti-MK-886-binding protein, Anti-Arachidonate 5-lipoxygenase-activating protein |
Application: | ELISA, IHC (paraffin), WB |
Host: | Goat |
Species reactivity: | human |
784.00€
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Item number: NSJ-R34221-100UG
0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: Five-lipoxygenase activating protein, ALOX5AP Protein function: Required for leukotriene biosynthesis by ALOX5 (5- lipoxygenase). Anchors ALOX5 to the membrane. Binds arachidonic acid, and could...
Keywords: | Anti-FLAP, Anti-ALOX5AP, Anti-MK-886-binding protein, Anti-Arachidonate 5-lipoxygenase-activating protein, FLAP Antibody |
Application: | WB, IHC, ELISA (peptide) |
Host: | Goat |
Species reactivity: | human |
755.00€
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Item number: Cay28600-1
GSK2190915 is a selective inhibitor of human 5-lipoxygenase-activating protein (FLAP, IC50 = 2.9 nM). It is selective for FLAP over 5-, 12-, and 15-lipoxygenase, leukotriene A4 (LTA4) hydrolase, LTC4 synthase, COX-1, and COX-2 (IC50s = >10 µm for all). GSK2190915 inhibits production of LTB4 induced by the calcium...
Keywords: | AM803,... |
Application: | FLAP (Arachidonate 5-lipoxygenase-activating protein) inhibitor |
CAS | 936350-00-4 |
MW: | 637.8 D |
147.00€
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Item number: ATA-HPA026592.100
Protein function: Required for leukotriene biosynthesis by ALOX5 (5- lipoxygenase). Anchors ALOX5 to the membrane. Binds arachidonic acid, and could play an essential role in the transfer of arachidonic acid to ALOX5. Binds to MK-886, a compound that blocks the biosynthesis of leukotrienes. [The UniProt Consortium]...
Keywords: | Anti-FLAP, Anti-ALOX5AP, Anti-MK-886-binding protein, Anti-Arachidonate 5-lipoxygenase-activating protein |
Application: | IHC, WB |
Host: | Rabbit |
Species reactivity: | human |
From 335.00€
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Item number: G-CAB19632.100
Protein function: Required for leukotriene biosynthesis by ALOX5 (5- lipoxygenase). Anchors ALOX5 to the membrane. Binds arachidonic acid, and could play an essential role in the transfer of arachidonic acid to ALOX5. Binds to MK-886, a compound that blocks the biosynthesis of leukotrienes. [The UniProt Consortium]
Keywords: | Anti-FLAP, Anti-ALOX5AP, Anti-MK-886-binding protein, Anti-Arachidonate 5-lipoxygenase-activating protein, FLAP Rabbit mAb |
Host: | Rabbit |
Species reactivity: | human |
From 352.00€
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Item number: Cay37322-1
MK-0591 is an inhibitor of 5-lipoxygenase-activating protein (FLAP, IC50 = 1.6 nM for the human enzyme). It inhibits leukotriene B4 (LTB4, Cay-20110) biosynthesis in isolated rat neutrophils stimulated with the calcium ionophore A23187 (Cay-11016, IC50 = 6 nM) but does not inhibit 5-lipoxygenase (5-LO) in a...
Keywords: | L-686,708, Quiflapon,... |
Application: | FLAP inhibitor |
CAS | 136668-42-3 |
MW: | 587.2 D |
From 90.00€
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Item number: A1359-76B.100
This gene encodes a protein which, with 5-lipoxygenase, is required for leukotriene synthesis. Leukotrienes are arachidonic acid metabolites which have been implicated in various types of inflammatory responses, including asthma, arthritis and psoriasis. This protein localizes to the plasma membrane. Inhibitors of...
Application: | ELISA, WB |
Host: | Goat |
Species reactivity: | human |
909.00€
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Item number: A1359-76D.200
ALOX5AP is a protein which, with 5-lipoxygenase, is required for leukotriene synthesis. Leukotrienes are arachidonic acid metabolites which have been implicated in various types of inflammatory responses, including asthma, arthritis and psoriasis. This protein localizes to the plasma membrane. Inhibitors of its...
Keywords: | Anti-MK-886-binding protein |
Application: | ELISA, IHC, WB |
Host: | Rabbit |
Species reactivity: | human |
728.00€
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Item number: A4776-20B.100
This gene encodes a protein which, with 5-lipoxygenase, is required for leukotriene synthesis. Leukotrienes are arachidonic acid metabolites which have been implicated in various types of inflammatory responses, including asthma, arthritis and psoriasis. This protein localizes to the plasma membrane. Inhibitors of...
Keywords: | Anti-Arachidonate 5-lipoxygenase-activating protein |
Application: | ELISA, WB |
Host: | Goat |
Species reactivity: | dog, human |
840.00€
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