31 products were found matching "K19882"!
No results were found for the filter!
ABC99
Item number: Cay25858-1
ABC99 is an N-hydroxyhydantoin (NHH) carbamate that inhibits the Wnt-deacylating enzyme NOTUM (IC50 = 13 nM). It preserves Wnt3A signaling in the presence of NOTUM (EC50 = 89 nM in a cell-based reporter assay).Formal Name:...
| Keywords: | 7-(4-chlorobenzyl)-1,3-dioxohexahydroimidazo[1,5-a]pyrazin-2(3H)-yl-2,3-dihydro-4H-benzo[b][1,4]oxazine-4-carboxylate |
| Application: | NOTUM inhibitor |
| CAS | 2331255-53-7 |
| MW: | 456.9 D |
From 126.00€
*
Human NOTUM / Protein notum homolog ELISA Kit
Item number: G-HUFI01515.96
| Application: | ELISA |
| Species reactivity: | human |
698.00€
*
Anti-NOTUM
Item number: 600-401-DD7
Anti-NOTUM Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with NOTUM from other sources has not been determined. Protein function: May deacetylate GlcNAc residues on cell surface glycans. [The UniProt Consortium]
| Keywords: | Anti-NOTUM, EC=3.-.-.-, Anti-Protein notum homolog |
| Application: | ELISA, IHC, IFM, WB |
| Host: | Rabbit |
| Species reactivity: | human, mouse, rat |
848.00€
*
Palmitoleoyl-protein carboxylesterase NOTUM (NOTUM),...
Item number: CSB-EP747435HU.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 20-496aa. Protein Length: Full Length of Mature Protein. Tag Info: N-terminal 6xHis-tagged. Target Protein Sequence: SEGRKTWRRR GQQPPPPPRT EAAPAAGQPV ESFPLDFTAV EGNMDSFMAQ VKSLAQSLYP CSAQQLNEDL RLHLLLNTSV TCNDGSPAGY YLKESRGSRR WLLFLEGGWY CFNRENCDSR...
| Keywords: | hNOTUM, Palmitoleoyl-protein carboxylesterase NOTUM, Recombinant Human Palmitoleoyl-protein carboxylesterase NOTUM (NOTUM) |
| Application: | Activity not tested |
| Expressed in: | E.coli |
| Origin: | human |
| MW: | 57.8 kD |
From 292.00€
*
NOTUM Protein, Human, Recombinant (His)
Item number: TGM-TMPH-01825-100ug
Description: Carboxylesterase that acts as a key negative regulator of the Wnt signaling pathway by specifically mediating depalmitoleoylation of WNT proteins. Serine palmitoleoylation of WNT proteins is required for efficient binding to frizzled receptors. NOTUM Protein, Human, Recombinant (His) is expressed in E....
| Keywords: | NOTUM, hNOTUM, Palmitoleoyl-protein carboxylesterase NOTUM |
| MW: | 57.8 kD |
From 266.00€
*
ARUK3001185
Item number: TGM-T60537-100mg
Description: ARUK3001185 (Compound 8l) is a potent, selective, orally active, and brain-penetrant Notum inhibitor (IC50 = 6.7 nM), suitable for oral dosing in rodent models of disease [1]. Target: Others. Smiles: C(F)(F)(F)C1=C(Cl)C(=CC=C1Cl)N2C=CN=N2
| Application: | NOTUM inhibitor |
| CAS | 2411969-39-4 |
| MW: | 282.05 D |
From 89.00€
*
NEW
Anti-Notum
Item number: CSB-PA784750XA01DLU.100
Make to order. Production time: 70-80 business days. Deliverables: 1. 200 µg antigen (used as positive control), 2. 1 ml pre-immune serum (used as negative control) , 3. Rabbit polyclonal antibody, antigen affinity purified. Quality Guarantee: 1. Antibody purity > 90% confirmed by SDS-PAGE, 2. Antibody titer > 1:...
| Keywords: | Anti-dNOTUM, Anti-Protein Notum, Anti-Protein wingful, Anti-Palmitoleoyl-protein carboxylesterase NOTUM, Notum Antibody |
| Application: | ELISA, WB |
| Host: | Rabbit |
| Species reactivity: | Drosophila melanogaster (Fruit fly) |
1,529.00€
*
NOTUM Protein, Human, Recombinant (His)
Item number: TGM-TMPH-01825-10ug
Description: Carboxylesterase that acts as a key negative regulator of the Wnt signaling pathway by specifically mediating depalmitoleoylation of WNT proteins. Serine palmitoleoylation of WNT proteins is required for efficient binding to frizzled receptors. NOTUM Protein, Human, Recombinant (His) is expressed in E....
| Keywords: | Palmitoleoyl-protein carboxylesterase NOTUM , hNOTUM , NOTUM |
| MW: | 57.8 kD |
From 99.00€
*
Anti-PAE12
Item number: CSB-PA446474XA01DOA.100
Make to order. Production time: 70-80 business days. Deliverables: 1. 200 µg antigen (used as positive control), 2. 1 ml pre-immune serum (used as negative control) , 3. Rabbit polyclonal antibody, antigen affinity purified. Quality Guarantee: 1. Antibody purity > 90% confirmed by SDS-PAGE, 2. Antibody titer > 1:...
| Keywords: | Anti-Pectin acetylesterase 12, PAE12 Antibody |
| Application: | ELISA, WB |
| Host: | Rabbit |
| Species reactivity: | Arabidopsis thaliana (Mouse-ear cress) |
1,529.00€
*
ARUK3001185
Item number: Cay37113-1
ARUK3001185 is an inhibitor of palmitoleoyl-protein carboxylesterase NOTUM (IC50 = 6.7 nM), an enzyme involved in the deacylation of Wnt. It is selective for NOTUM over a panel of 39 serine hydrolases and 485 kinases, including casein kinase 1 (CK1) and glycogen synthase kinase 3 (GSK3), at 10 µM and a panel of 47...
| Keywords: | 1-Phenyl-1H-1,2,3-triazole 1, 1-[2,4-dichloro-3-(trifluoromethyl)phenyl]-1H-1,2,3-triazole |
| Application: | NOTUM inhibitor |
| CAS | 2411969-39-4 |
| MW: | 282.1 D |
From 78.00€
*
Mouse Protein notum homolog (NOTUM) ELISA kit
Item number: CSB-EL015955MO.48
Sample Types: serum, plasma, tissue homogenates, cell culture supernates Detection Range: 0.156 ng/mL-10 ng/mL Sensitivity: 0.039 ng/mL Assay Principle: quantitative Measurement: SandwichAssay Time: 1-5h Sample Volume: 50-100ulDetection Wavelength: 450 nmProtein function: Carboxylesterase that acts as a key negative...
| Keywords: | Palmitoleoyl-protein carboxylesterase NOTUM |
| Application: | ELISA, Sandwich ELISA |
| Species reactivity: | mouse |
From 581.00€
*
Human Protein notum homolog (NOTUM) ELISA kit
Item number: CSB-EL015955HU.48
Sample Types: serum, plasma, tissue homogenates Detection Range: 1.56 ng/mL-100 ng/mL Sensitivity: 0.39 ng/mL Assay Principle: quantitative Measurement: SandwichAssay Time: 1-5h Sample Volume: 50-100ulDetection Wavelength: 450 nmProtein function: Carboxylesterase that acts as a key negative regulator of the Wnt...
| Keywords: | hNOTUM, Palmitoleoyl-protein carboxylesterase NOTUM |
| Application: | ELISA, Sandwich ELISA |
| Species reactivity: | human |
From 581.00€
*