88 products were found matching "K19722"!

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse AGER. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse AGER. Next,...

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human AGER. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human AGER. Next,...

Protein function: Mediates interactions of advanced glycosylation end products (AGE). These are nonenzymatically glycosylated proteins which accumulate in vascular tissue in aging and at an accelerated rate in diabetes. Acts as a mediator of both acute and chronic vascular inflammation in conditions such as...

Nepsilon-(1-Carboxymethyl)-L-lysine (CML) is an advanced glycation end product (AGE), produced by the oxidative modification of glycated proteins during oxidative stress. Levels of CML increase with aging and during diabetes, cancer, vascular disease, and other pathologies marked by oxidative stress. CML activates...

Advanced glycation end products (AGEs) are formed from the nonenzymatic reaction of amino groups with reducing sugars. AGEs have been implicated in diseases, such as diabetes mellitus, non-diabetic nephropathy, macrovascular disease, Alzheimer's disease, cataract, and ageing. AGE receptors, such as the receptor for...

FPS-ZM1 is a high-affinity inhibitor of the receptor for advanced glycation end products (RAGE, Ki = 25 nM). It blocks the binding of amyloid beta (Abeta) protein to RAGE and inhibits Abeta40- and Abeta42-induced cellular stress in RAGE-expressing cells. FPS-ZM1 is functional in mice when administered...

Nepsilon-(1-Carboxyethyl)-L-lysine (CEL) is an advanced glycation end product (AGE) produced by the reaction of methyl glyoxal with lysine residues in proteins. Protein bound, but not free, CEL binds to the receptor for AGEs (RAGE). CEL levels are elevated in the lens of diabetic patients with cataract. Long-term...

Nepsilon-(1-Carboxymethyl)-L-lysine-d3 (CML-d3) is intended for use as an internal standard for the quantification of CML (Cay-16483) by GC- or LC-MS. CML is an advanced glycation end product (AGE), produced by the oxidative modification of glycated proteins during oxidative stress. Levels of CML increase with aging...

Protein function: Mediates interactions of advanced glycosylation end products (AGE). These are nonenzymatically glycosylated proteins which accumulate in vascular tissue in aging and at an accelerated rate in diabetes. Acts as a mediator of both acute and chronic vascular inflammation in conditions such as...

Protein function: Mediates interactions of advanced glycosylation end products (AGE). These are nonenzymatically glycosylated proteins which accumulate in vascular tissue in aging and at an accelerated rate in diabetes. Acts as a mediator of both acute and chronic vascular inflammation in conditions such as...

Advanced glycation end products (AGEs) are formed from the nonenzymatic reaction of amino groups with reducing sugars.{38175, 38176, 38177} AGEs have been implicated in diseases, such as diabetes mellitus, non-diabetic nephropathy, macrovascular disease, Alzheimer's disease, cataract, and ageing. {38175, 38176,...