28 products were found matching "K19261"!
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Sisunatovir
Item number: Cay42124-10
An RSV fusion inhibitor (IC50 = 0.9 nM), reduces RSV A2 replication in a plaque reduction assay in vitro (EC50 = 1.3 nM), decreases lung viral titers in a mouse model of RSV infection at 1, 10, or 50 mg/kg. Formulation: A solid. InChI:...
| Keywords: | RV521,... |
| Application: | RSV fusion inhibitor |
| CAS | 1903763-82-5 |
| MW: | 446.44 D |
From 163.00€
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respiratory syncytial virus B Fusion glycoprotein F0 (F),...
Item number: CSB-YP516611HXK.1
Organism: Human respiratory syncytial virus B (strain B1). Source: Yeast. Expression Region: 137-574aa. Protein Length: Partial. Tag Info: N-terminal 6xHis-tagged. Target Protein Sequence: FLGFLLGVGS AIASGIAVSK VLHLEGEVNK IKNALLSTNK AVVSLSNGVS VLTSKVLDLK NYINNQLLPI VNQQSCRISN IETVIEFQQK NSRLLEINRE FSVNAGVTTP...
| Keywords: | F, Recombinant Human respiRatory syncytial virus B Fusion glycoprotein F0 (F), partial |
| Application: | Activity not tested |
| Expressed in: | Yeast |
| Origin: | Human respiratory syncytial virus B |
| MW: | 50.1 kD |
From 242.00€
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Sisunatovir
Item number: TGM-T24747-2mg
Description: RV521 is a highly effective fusion inhibitor. It designed to treat RSV disease by the target of a surface protein that mediates RSV binding to cellular receptors. Target: Others. Smiles: NCc1ccc2n(CCCC(F)(F)F)c(CN3C(=O)C4(CC4)c4ccc(F)cc34)nc2c1
| Keywords: | RV521, RV-521, RV 521, RV521 free base |
| Application: | Targets Pneumoviridae fusion glycoprotein F0 (F) |
| CAS | 1903763-82-5 |
| MW: | 446.44 D |
From 83.00€
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Clesrovimab
Item number: TGM-T77132-10mg
Description: Clesrovimab (MK1654) is an anti-respiratory syncytial virus protein F human monoclonal antibody for the prevention and treatment of respiratory syncytial virus infections. Target: Others. References: Qiu X, et al. Development of mRNA vaccines against respiratory syncytial virus (RSV). Cytokine Growth...
| Keywords: | MK-1654 |
| Application: | Targets Pneumoviridae fusion glycoprotein F0 (F) |
| CAS | 2429913-18-6 |
From 430.00€
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Palivizumab
Item number: TGM-T76907-100mg
Description: Palivizumab (MEDI 493) is a humanized RSV-specific monoclonal antibody that selectively inhibits epitopes at the F protein A antigenic site of RSV subtypes A and B for the prevention of respiratory syncytial virus infection (RSV). Target: RSV. References: Palivizumab, a humanized respiratory syncytial...
| Keywords: | MEDI 493, Synagis |
| Application: | Targets Pneumoviridae fusion glycoprotein F0 (F) |
| CAS | 188039-54-5 |
From 215.00€
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Sisunatovir hydrochloride
Item number: TGM-T9197-100mg
Description: Sisunatovir hydrochloride (RV521 HCl) is an orally available inhibitor of the RSV-F protein that has exhibited potent efficacy against a panel of clinical isolates of RSV-A and RSV-B viruses in vitro (IC50 = 1.4 nM for RSV-A, IC50 = 1.0 nM for RSV-B). Target: RSV. Smiles:...
| Keywords: | Sisunatovir HCl, RV521 HCl |
| Application: | Targets Pneumoviridae fusion glycoprotein F0 (F) |
| CAS | 1903763-83-6 |
| MW: | 482.9 D |
From 49.00€
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Presatovir
Item number: TGM-TQ0085-100mg
Description: Presatovir (GS-5806) (GS-5806) is a novel, orally bioavailable RSV fusion inhibitor (mean EC50: 0.43 nM). Target: RSV. Smiles: Cc1cn2nc(cc2nc1N1CC[C@H](N)C1)[C@@H]1CCCCN1C(=O)c1cc(Cl)ccc1NS(C)(=O)=O. References: Samuel D, et al. GS-5806 inhibits pre- to postfusion conformational changes of the...
| Keywords: | GS-5806 |
| Application: | Targets Pneumoviridae fusion glycoprotein F0 (F) |
| CAS | 1353625-73-6 |
| MW: | 532.06 D |
From 55.00€
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Nirsevimab (YTE Mutant)
Item number: BPS-83759-1
Nirsevimab, also known as MEDI8897, is a recombinant neutralizing monoclonal antibody developed against human respiratory syncytial virus (RSV). It is an IgG1kappa antibody, that has a triple mutation in the Fc region designed to increase its serum half-life. The YTE (M252Y/S254T/T256E) mutation increases the...
| Keywords: | F, Fusion glycoprotein F0 |
| Application: | Biochemical, cellular assays |
| Host: | Hamster |
| Species reactivity: | human |
| CAS | 1989556-22-0 |
From 1,500.00€
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Anti-RSV F (11A9), Epitope II, biotinylated
Item number: NOV-DA091BDL.100ug
Respiratory syncytial virus (RSV) is a highly contagious pathogen of the respiratory tract, primarily in infants and the elderly. A vaccine against RSV is currently not available, but is desired due to the high disease burden.RSV has two major surface glycoproteins (G and F) that play important roles in the initial...
| Keywords: | Anti-F, Biotinylated RSV F Antibody (11A9), Epitope II |
| Host: | Human |
| Species reactivity: | Biotinylated RSV F Antibody (11A9), Epitope II |
From 450.00€
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Anti-RSV Pre-F (3C12), Epitope Phi
Item number: NOV-DA101.100ug
Respiratory syncytial virus (RSV) is a highly contagious pathogen of the respiratory tract, primarily in infants and the elderly. A vaccine against RSV is currently not available, but is desired due to the high disease burden.RSV has two major surface glycoproteins (G and F) that play important roles in the initial...
| Keywords: | Anti-F, RSV Pre-F Antibody (3C12), Epitope Phi |
| Host: | Human |
| Species reactivity: | RSV Pre-F Antibody (3C12), Epitope Phi |
From 250.00€
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Anti-RSV F (4D5), Epitope I, biotinylated
Item number: NOV-DA102BDL.100ug
Respiratory syncytial virus (RSV) is a highly contagious pathogen of the respiratory tract, primarily in infants and the elderly. A vaccine against RSV is currently not available, but is desired due to the high disease burden.RSV has two major surface glycoproteins (G and F) that play important roles in the initial...
| Keywords: | Anti-F, Biotinylated RSV F Antibody (4D5), Epitope I |
| Host: | Human |
| Species reactivity: | Biotinylated RSV F Antibody (4D5), Epitope I |
From 495.00€
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Anti-RSV F (4B9), Epitope III
Item number: NOV-DA110.100ug
Respiratory syncytial virus (RSV) is a highly contagious pathogen of the respiratory tract, primarily in infants and the elderly. A vaccine against RSV is currently not available, but is desired due to the high disease burden.RSV has two major surface glycoproteins (G and F) that play important roles in the initial...
| Keywords: | Anti-F, RSV F Antibody (4B9), Epitope III |
| Host: | Human |
| Species reactivity: | RSV F Antibody (4B9), Epitope III |
From 328.00€
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