30 products were found matching "K19021"!

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Anti-PDE3A
Anti-PDE3A

Item number: A302-740A

Protein function: Cyclic nucleotide phosphodiesterase with a dual- specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. [The UniProt Consortium]
Keywords: Anti-PDE3A, Anti-CGI-PDE A, EC=3.1.4.17, Anti-Cyclic GMP-inhibited phosphodiesterase A, Anti-cGMP-inhibited 3',5'-cyclic...
Application: WB, IP
Host: Rabbit
Species reactivity: human
From 164.00€ *
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Rat PDE3A (Phosphodiesterase 3A, cGMP Inhibited) ELISA Kit
Rat PDE3A (Phosphodiesterase 3A, cGMP Inhibited) ELISA Kit

Item number: ELK-ELK7003.48

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat PDE3A. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat PDE3A. Next,...
Keywords: CGI-PDE A, Cyclic GMP-inhibited phosphodiesterase A, cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A
Application: ELISA
Species reactivity: rat
365.00€ * From 328.50€ *
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Ensifentrine
Ensifentrine

Item number: Cay38761-1

Ensifentrine is a phosphodiesterase 3 (PDE3) inhibitor (IC50 = 0.4 nM). It is selective for PDE3 over PDE4 (IC50 = 1,479 nM). Ensifentrine reduces phytohemagglutinin-induced proliferation of isolated human monocytes in a concentration-dependent manner and inhibits LPS-induced increases of TNF-alpha protein levels in...
Keywords: RPL 554, VMX 554,...
Application: PDE3 inhibitor
CAS 1884461-72-6
MW: 477.6 D
From 40.00€ *
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Anti-PDE3A
Anti-PDE3A

Item number: A302-741A

Protein function: Cyclic nucleotide phosphodiesterase with a dual- specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. [The UniProt Consortium]
Keywords: Anti-PDE3A, Anti-CGI-PDE A, EC=3.1.4.17, Anti-Cyclic GMP-inhibited phosphodiesterase A, Anti-cGMP-inhibited 3',5'-cyclic...
Application: WB, IP
Host: Rabbit
Species reactivity: human
From 164.00€ *
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PDE3B, active human recombinant protein
PDE3B, active human recombinant protein

Item number: BPS-60031

Active human PDE3B (GenBank Accession No. NM_000922), (amino acids 592-end), with N-terminal GST tag, MW = 86 kDa, expressed in a Baculovirus infected Sf9 cell expression system.
Keywords: cGI-PDE, CGI-PDE A, cGMP-inhibited cAMP phosphodiesterase, Cyclic GMP-inhibited phosphodiesterase A, cGMP-inhibited...
Application: Enzyme kinetics, inhibitor screening
MW: 86 kD
672.00€ *
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PDE3A (His-GST), active human recombinant protein
PDE3A (His-GST), active human recombinant protein

Item number: BPS-60032

Human PDE3A (GenBank Accession No. NM_000921), amino acids 669-1141(end), with N-terminal His-GST tag, MW = 82 kDa, expressed in a Baculovirus infected Sf9 cell expression system.
Keywords: cGI-PDE, CGI-PDE A, cGMP-inhibited cAMP phosphodiesterase, Cyclic GMP-inhibited phosphodiesterase A, cGMP-inhibited...
Application: Enzyme kinetics, inhibitor screening, selectivity profiling
Expressed in: Baculovirus
Origin: human
MW: 82 kD
672.00€ *
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Vesnarinone
Vesnarinone

Item number: Cay23489-1

Vesnarinone is an inhibitor of phosphodiesterase 3 (PDE3, IC50s = 10.7 and 13.2 µM for PDE3A and PDE3B, respectively). It also inhibits ether-a-go-go-related gene 1 (ERG1) channels (IC50 = 1.1 µM in HEK293T cells expressing human ERG1). Vesnarinone (3-300 µM) increases contractile tension in isolated ventricular...
Keywords: OPC 8212, 6-[4-(3,4-dimethoxybenzoyl)-1-piperazinyl]-3,4-dihydro-2(1H)-quinolinone
Application: PDE3 inhibitor
CAS 81840-15-5
MW: 395.5 D
From 43.00€ *
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Carbazeran
Carbazeran

Item number: Cay26092-1

Carbazeran is an inhibitor of phosphodiesterase 2 (PDE2) and PDE3. It inhibits cAMP hydrolysis (IC50 = 4.1 µM in rabbit heart ventricles) selectively over cGMP hydrolysis (IC50 = 171 µM). It induces positive inotropic (EC50 = 100 µM) and negative chronotropic effects in isolated rabbit papillary muscle and right...
Keywords: N-ethyl-carbamic acid, 1-(6,7-dimethoxy-1-phthalazinyl)-4-piperidinyl ester
Application: PDE2 / PDE3 inhibitor
CAS 70724-25-3
MW: 360.4 D
From 43.00€ *
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Anti-PDE3A
Anti-PDE3A

Item number: ARG10796.50

Protein function: Cyclic nucleotide phosphodiesterase with a dual- specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. [The UniProt Consortium]
Keywords: Anti-PDE3A, Anti-CGI-PDE A, EC=3.1.4.17, Anti-Cyclic GMP-inhibited phosphodiesterase A, Anti-cGMP-inhibited 3',5'-cyclic...
Application: IF, ELISA, FRET, ICC, IF, IHC (paraffin), IP, WB, DB
Host: Rabbit
Species reactivity: human, monkey, mouse, rat, Xenopus
576.00€ *
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PDE3A (Mouse), GST-Tag
PDE3A (Mouse), GST-Tag

Item number: BPS-60036

Mouse PDE3A (GenBank Accession No. NM_018779), amino acids 484-1141 end), with N-terminal GST tag, MW = 100 kDa, expressed in a Baculovirus infected Sf9 cell expression system.
Keywords: Phosphodiesterase,
Application: Enzyme kinetics, inhibitor screening, selectivity profiling
Expressed in: insect cells
Origin: mouse
MW: 100 kD
672.00€ *
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PDE3B Assay Kit
PDE3B Assay Kit

Item number: BPS-60383

The PDE3B Assay Kit is designed for identification of PDE3B inhibitors using fluorescence polarization. The assay is based on the binding of a fluorescent nucleotide monophosphate generated by PDE3B to the binding agent. The key to the PDE3B Assay Kit is the specific binding agent. Using this kit, only two simple...
Keywords: PDE3B, phosphodiesterase 3B,
Application: Enzyme kinetics, inhibitor screening, drug discovery, HTS
Species reactivity: human
1,173.00€ *
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Amrinone
Amrinone

Item number: Cay23898-1

Amrinone is an inhibitor of phosphodiesterase 3 (PDE3, IC50 = 19.5 µM). It increases developed tension and contractile force in isolated cat papillary muscle. Amrinone (1-10 mg/kg) has positive inotropic effects, increasing the rate and force of heart contraction in anesthetized and unanesthetized dogs.Formal Name:...
Keywords: WIN 40,680, 5-amino-[3,4'-bipyridin]-6(1H)-one
Application: PDE3 inhibitor
CAS 60719-84-8
MW: 187.2 D
From 60.00€ *
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