101 products were found matching "K18754"!

Lin28 1632 is a small molecule inhibitor of the interaction between the RNA binding protein Lin28 and let-7 precursor RNA (IC50 = 8 µM in a competition ELISA). It increases levels of endogenous let-7 miRNAs and decreases Lin28 expression in a dose-dependent manner in murine embryonic stem cells (mESCs). Lin28 1632...

Protein function: Acts as a 'translational enhancer', driving specific mRNAs to polysomes and thus increasing the efficiency of protein synthesis. Its association with the translational machinery and target mRNAs results in an increased number of initiation events per molecule of mRNA and, indirectly, in stabilizing...

Protein function: 'Translational enhancer' that drives specific mRNAs to polysomes and increases the efficiency of protein synthesis. Its association with the translational machinery and target mRNAs results in an increased number of initiation events per molecule of mRNA and, indirectly, in mRNA stabilization....

Protein function: Suppressor of microRNA (miRNA) biogenesis, including that of let-7 and possibly of miR107, miR-143 and miR-200c. Binds primary let-7 transcripts (pri-let-7), including pri-let-7g and pri-let-7a-1, and sequester them in the nucleolus, away from the microprocessor complex, hence preventing their...

Protein function: Suppressor of microRNA (miRNA) biogenesis, including that of let-7 and possibly of miR107, miR-143 and miR-200c. Binds primary let-7 transcripts (pri-let-7), including pri-let-7g and pri-let-7a-1, and sequester them in the nucleolus, away from the microprocessor complex, hence preventing their...

Human LIN28A, also known as Lin-28 Homolog A, with N-terminal FLAG-Avi-Tag, GenBank Accession No. NM_024674, a.a. 2-209 (end), expressed in a HEK293 cell expression system. MW = 26 kDa.

Human LIN28B, also known as Lin-28 Homolog B, with N-terminal FLAG-Avi-Tag, GenBank Accession No. NM_001004317, a.a. 2-250 (end), expressed in a HEK293 cell expression system. MW = 30 kDa.

Anti-Lin28 Monoclonal Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. At least two isoforms of Lin28 are known to exist, this antibody will detect both. Lin28 antibody will not cross-react with Lin28 Homolog B. Protein function: Acts as a 'translational enhancer', driving...

Anti-Lin28 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with Lin28 from other sources has not been determined. Protein function: Acts as a 'translational enhancer', driving specific mRNAs to polysomes and thus increasing the efficiency of protein...

In 1X PBS, pH 7.4, with 0.09% sodium azide. Lin-28 homolog B (LIN28B) is overexpressed in hepatocellular carcinoma. The heterochronic gene lin-28 is a key regulator of developmental timing in the nematode Caenorhabditis elegans. Similar with lin-28 proteins, LIN28B conserves a cold shock domain and a pair of CCHC...

In 1X PBS, pH 7.4, with 0.09% sodium azide. LIN28 is probable transcription factor. It plays a critical role in the control of immune response. Protein function: 'Translational enhancer' that drives specific mRNAs to polysomes and increases the efficiency of protein synthesis. Its association with the translational...