73 products were found matching "K18754"!

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human LIN28A. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human LIN28A....

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse LIN28A. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse LIN28A....

Lin28 1632 is a small molecule inhibitor of the interaction between the RNA binding protein Lin28 and let-7 precursor RNA (IC50 = 8 µM in a competition ELISA). It increases levels of endogenous let-7 miRNAs and decreases Lin28 expression in a dose-dependent manner in murine embryonic stem cells (mESCs). Lin28 1632...

WB 1:500 - 1:2000, IF 1:50 - 1:200. Protein function: Suppressor of microRNA (miRNA) biogenesis, including that of let-7 and possibly of miR107, miR-143 and miR-200c. Binds primary let-7 transcripts (pri-let-7), including pri-let-7g and pri-let-7a-1, and sequester them in the nucleolus, away from the microprocessor...

Protein function: Acts as a 'translational enhancer', driving specific mRNAs to polysomes and thus increasing the efficiency of protein synthesis. Its association with the translational machinery and target mRNAs results in an increased number of initiation events per molecule of mRNA and, indirectly, in stabilizing...

Protein function: 'Translational enhancer' that drives specific mRNAs to polysomes and increases the efficiency of protein synthesis. Its association with the translational machinery and target mRNAs results in an increased number of initiation events per molecule of mRNA and, indirectly, in mRNA stabilization....

Protein function: Suppressor of microRNA (miRNA) biogenesis, including that of let-7 and possibly of miR107, miR-143 and miR-200c. Binds primary let-7 transcripts (pri-let-7), including pri-let-7g and pri-let-7a-1, and sequester them in the nucleolus, away from the microprocessor complex, hence preventing their...

Protein function: Suppressor of microRNA (miRNA) biogenesis, including that of let-7 and possibly of miR107, miR-143 and miR-200c. Binds primary let-7 transcripts (pri-let-7), including pri-let-7g and pri-let-7a-1, and sequester them in the nucleolus, away from the microprocessor complex, hence preventing their...

Human LIN28A, also known as Lin-28 Homolog A, with N-terminal FLAG-Avi-Tag, GenBank Accession No. NM_024674, a.a. 2-209 (end), expressed in a HEK293 cell expression system. MW = 26 kDa.

Human LIN28B, also known as Lin-28 Homolog B, with N-terminal FLAG-Avi-Tag, GenBank Accession No. NM_001004317, a.a. 2-250 (end), expressed in a HEK293 cell expression system. MW = 30 kDa.

Anti-Lin28 Monoclonal Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. At least two isoforms of Lin28 are known to exist, this antibody will detect both. Lin28 antibody will not cross-react with Lin28 Homolog B. Protein function: Acts as a 'translational enhancer', driving...