43 products were found matching "K18436"!

Active human PDE7A1 GenBank Accession No. NM_002603), (a.a. 121-end) with N-terminal GST tag, MW=66 kDa, expressed in a Baculovirus infected Sf9 cell expression system.

Theophylline is a methylxanthine alkaloid that is a competitive inhibitor of phosphodiesterase (PDE, Ki = 100 µM). It is also a non-selective antagonist of adenosine A receptors (Ki = 14 µM for A1 and A2). Theophylline induces relaxation of feline bronchiole smooth muscle precontracted with acetylcholine (EC40 = 117...

BRL 50481 is a potent, selective inhibitor of phosphodiesterase (PDE) 7, inhibiting human recombinant PDE7A1 with a Ki value of 180 nM. It is much less effective against PDE3 and PDE4 and is without effect against PDE1B, PDE1C, PDE2, and PDE5. Through its effects on PDE7A1, BRL 50481 enhances the inhibitory effects...

Active human PDE7B GenBank Accession No. NM_018945), (a.a. 107-end) with N-terminal GST tag, MW=66 kDa, expressed in a Baculovirus infected Sf9 cell expression system.

Protein function: Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. May have a role in muscle signal transduction. [The UniProt Consortium]

Protein function: Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. May be involved in the control of cAMP-mediated neural activity and cAMP metabolism in the brain. [The UniProt Consortium]

Mouse PDE7A (GenBank Accession No. NM_001122759), a.a. 147-482(end), with N-terminal GST-tag, MW=65 kDa, expressed in a Baculovirus-infected Sf9 cell expression system. 1 unit is defined as the amount of enzyme that wi

Mouse PDE7B (GenBank Accession No. NM_013875), a.a. 108-446(end), with N-terminal GST-tag, MW=65 kDa, expressed in a Baculovirus-infected Sf9 cell expression system. Assay condition: 10 mM Tris-HCl, pH 7.4, 10 mM MgCl2,

Rat PDE7A (GenBank Accession No. NM_031080), amino acids 147-482(end), with N-terminal GST-tag, MW=65 kDa, expressed in a Baculovirus-infected Sf9 cell expression system. Specific Activity is 354 pmol/min/µg.

Rat PDE7A (GenBank Accession No. NM_031080), amino acids 147-482(end), with N-terminal GST-tag, MW=65 kDa, expressed in a Baculovirus-infected Sf9 cell expression system. Specific Activity is 354 pmol/min/µg.

Phosphodiesterases (PDEs) play an important role in dynamic regulation of cAMP and cGMP signaling. PDE7A is widely expressed in various tissues including skeletal muscle, T lymphocytes, brain and pancreas and plays and important role in the regulation of osteoblastic differentiation. The PDE7A Assay Kit is designed...

Phosphodiesterases (PDEs) play an important role in dynamic regulation of cAMP and cGMP signaling. PDE7B is highly expressed in the pancreas and in other various tissues. Inhibition of PDE7B leads to induction of apoptosis. The PDE7B Assay Kit is designed for identification of PDE7B inhibitors using fluorescence...