29 products were found matching "K17726"!

Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml. CYP4F2 antibody detects Cytochrome P450 4F2, encoded by the CYP4F2 gene on chromosome 19p13.12. CYP4F2 antibody is widely used to study this endoplasmic reticulum-anchored monooxygenase belonging to the cytochrome P450 superfamily. CYP4F2...

20-HEPE is a metabolite of eicosapentaenoic acid (EPA, Cay-90110, Cay-21908, Cay-90110.1) that is formed via omega-oxidation of EPA by cytochrome P450 (CYP) omega-oxidases, including human CYP4F3B. It activates peroxisome proliferator-activated receptor alpha (PPARalpha) in COS-7 cells expressing a luciferase...

22-HDHA is an oxidation product of docosahexaenoic acid (DHA, Cay-90310). In vitro, it is formed upon incubation of rat liver microsomes with DHA and NADPH and also by the human cytochrome P450 (CYP) isoform CYP4F3B in BTI-TN-5B1-4 microsomes. Serum levels of 22-HDHA increase following dietary DHA supplementation in...

Protein function: A cytochrome P450 monooxygenase involved in the metabolism of various endogenous substrates, including fatty acids, eicosanoids and vitamins (PubMed:18577768, PubMed:10833273, PubMed:10660572, PubMed:11997390, PubMed:17341693, PubMed:18574070). Mechanistically, uses molecular oxygen inserting one...

Protein function: A cytochrome P450 monooxygenase involved in the metabolism of various endogenous substrates, including fatty acids, eicosanoids and vitamins (PubMed:18577768, PubMed:10833273, PubMed:10660572, PubMed:11997390, PubMed:17341693, PubMed:18574070). Mechanistically, uses molecular oxygen inserting one...

TS-011 is an inhibitor of 20-hydroxyeicosatetraenoic acid (20-HETE) synthesis. It inhibits 20-HETE synthesis in human and rat renal microsomes (IC50s = 8.42 and 9.19 nM, respectively), as well as by the cytochrome P450 (CYP) isoforms CYP4F2, CYP4F3A, CYP4F3B, and CYP4A11 in cell-free assays (IC50s = 30.4, 42.6,...

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human CYP4F2. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human CYP4F2....

18-hydroxy Oleoyl leucine-d7 is intended for use as an internal standard for the quantification of 18-hydroxy oleoyl leucine by GC- or LC-MS. 18-hydroxy oleoyl leucine is a omega-hydroxy metabolite of the N-acyl amide mitochondrial uncoupling agent N-oleoyl leucine (Cay-20064). It is formed from N-oleoyl leucine by...

Oleic acid-hydroxy oleoyl leucine-d7 is intended for use as an internal standard for the quantification of oleic acid-hydroxy oleoyl leucine by GC- or LC-MS. Oleic acid-hydroxy oleoyl leucine is a very long-chain fatty acid composed of oleic acid (Cay-90260, Cay-24659) connected to hydroxy oleoyl leucine.Synonyms:...

Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...

Host Species: Rabbit. Isotype: IgG. Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by...

TP-0472993 is an inhibitor of the cytochrome P450 (CYP) isoforms CYP4A11 and CYP4F2 (IC50s = 140 and 40 nM, respectively). It is selective for CYP4A11 and CYP4F2 over a panel of eight additional CYPs at 10 µM. TP-0472993 inhibits 20-HETE (Cay-90030) production in rat renal microsomes (IC50 = 347 nM). In vivo,...