48 products were found matching "K17721"!

Formulation: Phosphate-buffered saline (PBS) with 50% glycerol, 0.5% BSA and 0.09% sodium azide. Identity-Mouse (%): 68%. Homologies: Highest antigen sequence identity to the following orthologs: Mouse - 68%, Rat - 79%, Pig - 80%, Cynomolgus monkey - 91%. IHC Verification: succeed. WB Verification: -. IP...

Formulation: Phosphate-buffered saline (PBS) with 50% glycerol, 0.5% BSA and 0.09% sodium azide. Identity-Mouse (%): 68%. Homologies: Highest antigen sequence identity to the following orthologs: Mouse - 68%, Rat - 79%, Pig - 80%, Cynomolgus monkey - 91%. IHC Verification: succeed. WB Verification: -. IP...

5-hydroxy Omeprazole is a metabolite of the H+/K+-ATPase inhibitor omeprazole (Cay-14880). It is formed from omeprazole by the cytochrome P450 (CYP) isoform CYP2C19.Formal Name: 4-methoxy-6-[[(6-methoxy-1H-benzimidazol-2-yl)sulfinyl]methyl]-5-methyl-3-pyridinemethanol. CAS Number: 92340-57-3. Synonyms: 5-hydroxy...

(±)4-Hydroxymephenytoin is a metabolite of (R)-mephenytoin (Cay-25891) and (S)-mephenytoin (Cay-11913). It is formed from (R)- and (S)-mephenytoin by the cytochrome P450 (CYP) isoform CYP2C19 in the liver.Formal Name: 5-ethyl-5-(4-hydroxyphenyl)-3-methyl-2,4-imidazolidinedione. CAS Number: 61837-65-8. Molecular...

(±)-N-3-Benzylnirvanol is a racemic mixture of (+)-N-3-benzylnirvanol and (-)-N-3-benzylnirvanol. (+)-N-3-benzylnirvanol and (-)-N-3-benzylnirvanol are inhibitors of the cytochrome P450 (CYP) isoform CYP2C19 (Kis = 0.25 and 5.3 µM, respectively). (±)-N-3-Benzylnirvanol (20 mg/kg, i.p.) lowers plasma levels of...

Clopidogrel carboxylic acid is an inactive metabolite of (±)-clopidogrel (Cay-13657) and (S)-(+)-clopidogrel (Cay-21002). It is formed from (±)-clopidogrel and (S)-(+)-clopidogrel by carboxylesterase 1 (CES1).Formal Name: alphaS-(2-chlorophenyl)-6,7-dihydro-thieno[3,2-c]pyridine-5(4H)-acetic acid, monohydrochloride....

Voriconazole N-oxide is a major metabolite of the triazole antifungal voriconazole (Cay-15633). It is formed via oxidation of voriconazole by the cytochrome P450 (CYP) isoforms CYP3A4 and CYP2C19.Formal Name:...

Light red to brown powder. Soluble in DMSO. Used in fluorimetric studies. Fluorescent probe. Selective fluorometric substrate for CYP2C19 and CYP1A1. Reaction product of the substrate 3-O-methylfluorescein phosphate (OMFP) is hydrolyzed by phosphatases to yield O-methylfluorescein (OMF) that is detected at a 485nm...

Stiripentol is a third-generation antiepileptic compound. It is a positive allosteric modulator of GABAA receptors, potentiating GABA-mediated activation to a greater extent in receptors expressing alpha3 subunits and to a lower extent in those containing beta1 or epsilon subunits. It also inhibits GABA reuptake in...

Pantoprazole sulfide is a metabolite of the gastric H+/K+ ATPase pump inhibitor pantoprazole (Cay-21345). Pantoprazole is metabolized by the cytochrome P450 (CYP) isomers CYP2C19 and CYP3A4 to form pantoprazole sulfide.Formal Name: 6-(difluoromethoxy)-2-[[(3,4-dimethoxy-2-pyridinyl)methyl]thio]-1H-benzimidazole. CAS...

Omeprazole sulfone is a metabolite of the inhibitor of gastric H+/K+ ATPase omeprazole (Cay-14880). It is formed from omeprazole by the cytochrome P450 (CYP) isoform CYP3A4.Formal Name: 6-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfonyl]-1H-benzimidazole. CAS Number: 88546-55-8. Synonyms: OMEP...