27 products were found matching "K17718"!
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N-desethyl Amodiaquine (hydrochloride)
Item number: Cay20822-1
N-desethyl Amodiaquine is a primary metabolite of the antimalarial compound aminodiaquine (Cay-15954), produced by the action of cytochrome P450 isoform 2C8. N-desethyl Amodiaquine is highly active against P. falciparum and can synergize with amodiaquine.Formal Name:...
| Keywords: | 4-[(7-chloro-4-quinolinyl)amino]-2-[(ethylamino)methyl]-phenol, dihydrochloride |
| Application: | Primary aminodiaquine metabolite |
| CAS | 79049-30-2 |
| MW: | 400.7 D |
From 49.00€
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Carbamazepine 10,11-epoxide
Item number: Cay33908-5
Carbamazepine 10,11-epoxide is an active metabolite of the anticonvulsant carbamazepine. It is formed from carbamazepine by the cytochrome P450 (CYP) isoforms CYP3A4 and CYP2C8 in microsomes prepared from HepG2 cells expressing CYP3A4 or CYP2C8, respectively. Carbamazepine 10,11-epoxide has anticonvulsant activity...
| Keywords: | CBZ 10,11-epoxide, CBZ-E, 1a,10b-dihydro-6H-dibenz[b,f]oxireno[d]azepine-6-carboxamide |
| Application: | Carbamazepine active metabolite |
| CAS | 36507-30-9 |
| MW: | 252.3 D |
From 85.00€
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Anti-CYP2C8
Item number: NSJ-R34557-100UG
0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: Cytochrome P450 2C8 Protein function: Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway....
| Keywords: | Anti-CYP2C8, Anti-CYPIIC8, Anti-Cytochrome P450 2C8, Anti-Cytochrome P450 IIC2, Anti-Cytochrome P450 MP-12,... |
| Application: | WB, ELISA (peptide) |
| Host: | Goat |
| Species reactivity: | human |
836.00€
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N-desmethyl Rosiglitazone
Item number: Cay22103-1
N-desmethyl Rosiglitazone is a major metabolite of rosiglitazone (Cay-71740, Cay-71742, Cay-11884), a potent and selective PPARgamma ligand present in formulations that have been used to treat type 2 diabetes. Rosiglitazone is metabolized by the cytochrome P450 (CYP) isoform CYP2C8 to form N-desmethyl...
| Keywords: | SB-237216, 5-[[4-[2-(2-pyridinylamino)ethoxy]phenyl]methyl]-2,4-thiazolidinedione |
| Application: | Rosiglitazone metabolite |
| CAS | 257892-31-2 |
| MW: | 343.4 D |
From 155.00€
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Hydroxy Pioglitazone
Item number: Cay28043-1
Hydroxy pioglitazone is a major metabolite of the peroxisome proliferator-activated receptor gamma (PPARgamma) agonist pioglitazone (Cay-71745, Cay-22263, Cay-10028). It is formed from pioglitazone by the cytochrome P450 (CYP) isoform CYP2C8 with minor contributions from CYP3A4. Hydroxy pioglitazone binds to...
| Keywords: | 5-[[4-[2-[5-(1-hydroxyethyl)-2-pyridinyl]ethoxy]phenyl]methyl]-2,4-thiazolidinedione |
| Application: | Major metabolite |
| CAS | 146062-44-4 |
| MW: | 372.4 D |
From 409.00€
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Desethyl Hydroxychloroquine
Item number: Cay31152-1
Desethyl hydroxychloroquine is an active metabolite of hydroxychloroquine (Cay-17911). It is formed via the desethylation of hydroxychloroquine in the liver, a process mediated by the cytochrome P450 (CYP) isoforms CYP2D6, CYP3A4, CYP3A5, and CYP2C8.Formal Name:...
| Keywords: | (±)-Desethylhydroxychloroquine, Cletoquine, DHCQ, 2-[[4-[(7-chloro-4-quinolinyl)amino]pentyl]amino]-ethanol |
| Application: | Active hydroxychloroquine metabolite |
| CAS | 4298-15-1 |
| MW: | 307.8 D |
450.00€
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Desethyl Hydroxychloroquine-d4
Item number: Cay31162-1
Desethyl hydroxychloroquine-d4 is intended for use as an internal standard for the quantification of desethyl hydroxychloroquine (Cay-31152) by GC- or LC-MS. Desethyl hydroxychloroquine is an active metabolite of hydroxychloroquine (Cay-17911). It is formed via the desethylation of hydroxychloroquine in the liver, a...
| Keywords: | (±)-Desethylhydroxychloroquine-d4, Cletoquine-d4, DHCQ-d4,... |
| Application: | GC-MS, LC-MS, internal standard |
| CAS | 1854126-47-8 |
| MW: | 311.8 D |
From 246.00€
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Anti-CYP2C8/CYP2C9/CYP2C18/CYP2C19 (PACO02540)
Item number: G-PACO02540.50
CYP2C8/CYP2C9/CYP2C18/CYP2C19 Antibody from Assay Genie with reactivity against Human and for use in ELISA, WB, IHC, IF applications. CYP2C8/CYP2C9/CYP2C18/CYP2C19 Antibody is Polyclonal and is a IgG isotype antibody from Assay Genie.. Protein function: A cytochrome P450 monooxygenase involved in the metabolism of...
| Keywords: | Anti-CYPIIC8, Anti-Cytochrome P450 2C8, Anti-Cytochrome P450 IIC2, Anti-Cytochrome P450 MP-20, Anti-Cytochrome P450 MP-12,... |
| Application: | ELISA, WB, IHC, IF |
| Host: | Rabbit |
| Species reactivity: | human |
225.00€
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Anti-CYP2C8
Item number: ATA-HPA013547.100
Protein function: A cytochrome P450 monooxygenase involved in the metabolism of various endogenous substrates, including fatty acids, steroid hormones and vitamins (PubMed:7574697, PubMed:11093772, PubMed:14559847, PubMed:15766564, PubMed:19965576). Mechanistically, uses molecular oxygen inserting one oxygen atom...
| Keywords: | Anti-CYPIIC8, Anti-Cytochrome P450 2C8, Anti-Cytochrome P450 IIC2, Anti-Cytochrome P450 MP-20, Anti-Cytochrome P450 MP-12,... |
| Application: | IHC, WB |
| Host: | Rabbit |
| Species reactivity: | human |
From 330.00€
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Anti-CYP2C8
Item number: ATA-HPA013970.100
Protein function: A cytochrome P450 monooxygenase involved in the metabolism of various endogenous substrates, including fatty acids, steroid hormones and vitamins (PubMed:7574697, PubMed:11093772, PubMed:14559847, PubMed:15766564, PubMed:19965576). Mechanistically, uses molecular oxygen inserting one oxygen atom...
| Keywords: | Anti-CYPIIC8, Anti-Cytochrome P450 2C8, Anti-Cytochrome P450 IIC2, Anti-Cytochrome P450 MP-20, Anti-Cytochrome P450 MP-12,... |
| Application: | IHC, WB |
| Host: | Rabbit |
| Species reactivity: | human |
From 330.00€
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6alpha-hydroxy Paclitaxel-d5
Item number: Cay40926-1
An internal standard for the quantification of 6alpha-hydroxy paclitaxel 6alpha-hydroxy Paclitaxel-d5 is intended for use as an internal standard for the quantification of 6alpha-hydroxy paclitaxel (Cay-10009027) by GC- or LC-MS. 6alpha-hydroxy Paclitaxel is a metabolite of the antimitotic and anticancer agent...
| Keywords: | 6alpha-hydroxy Taxol-d5, (alphaR,betaS)-beta-(benzoyl-2,3,4,5,6-d5-amino)-alpha-hydroxy-benzenepropanoic acid,... |
| Application: | GC-MS, LC-MS internal standard, quantification, paclitaxel metabolite |
| CAS | 1315376-90-9 |
| MW: | 874.9 D |
2,370.00€
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Cytochrome P450 2C8 (CYP2C8), human, recombinant
Item number: CSB-EP006418HU.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 27-490aa. Protein Length: Full Length of Mature Protein. Tag Info: N-terminal 10xHis-tagged and C-terminal Myc-tagged. Target Protein Sequence: RKLPPGPTPL PIIGNMLQID VKDICKSFTN FSKVYGPVFT VYFGMNPIVV FHGYEAVKEA LIDNGEEFSG RGNSPISQRI TKGLGIISSN...
| Keywords: | CYPIIC8, Cytochrome P450 2C8, Cytochrome P450 IIC2, Cytochrome P450 MP-20, Cytochrome P450 MP-12, Cytochrome P450 form 1,... |
| Application: | Activity not tested |
| Expressed in: | E.coli |
| Origin: | human |
| MW: | 60.1 kD |
From 292.00€
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