36 products were found matching "K17683"!

(±)-Cotinine-d3 is intended for use as an internal standard for the quantification of cotinine by GC- or LC-MS. Cotinine is an alkaloid found in tobacco and a major metabolite of nicotine (Cay-16535). It is formed by oxidation of nicotine by the cytochrome P450 (CYP) isoform CYP2A6.Formal Name:...

trans-3'-Hydroxycotinine (3HC) is a product of CYP2A6 metabolism of the primary nicotine metabolite, cotinine (Cay-15314). Cotinine has a longer metabolic half-life compared to 3HC (16 hours vs. 5 hours). The ratio of 3HC to cotinine, termed the nicotine metabolite ratio, correlates with nicotine clearance from the...

beta-Nicotyrine is an alkaloid that has been found in tobacco. It reduces the number of dsDNA breaks induced by the tobacco-specific carcinogen nitrosamine (4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone, Cay-16414) in a comet assay using HepaRG hepatocellular carcinoma cells when used at concentrations of 5 and 50...

CYP2A6/CYP2A7/CYP2A13 Antibody from Assay Genie with reactivity against Human and for use in ELISA, WB applications. CYP2A6/CYP2A7/CYP2A13 Antibody is Polyclonal and is a IgG isotype antibody from Assay Genie.. Protein function: Exhibits a high coumarin 7-hydroxylase activity. Can act in the hydroxylation of the...

Hydroxymetronidazole is an active metabolite of the antibiotic metronidazole (Cay-9002409). It is formed from metronidazole primarily by the cytochrome P450 (CYP) isoform CYP2A6. Hydroxymetronidazole is active against B. fragilis, B. thetaiotaomicron, B. distasonis, and B. ovatus (MICs = 1, 2, 1, and 2 µg/ml,...

7-Methylcoumarin is an inhibitor for CYP2A6. It has strong hepatoprotective activity, which could be attributed to its potent antioxidant effects. 7-Methylcoumarin has moderate antimicrobial activity. The compound can be used as internal standard during HPLC analysis.

Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 29-494aa. Protein Length: Partial. Tag Info: N-terminal 10xHis-tagged and C-terminal Myc-tagged. Target Protein Sequence: SKGKLPPGPT PLPFIGNYLQ LNTEQMYNSL MKISERYGPV FTIHLGPRRV VVLCGHDAVR EALVDQAEEF SGRGEQATFD WVFKGYGVVF SNGERAKQLR RFSIATLRDF...

Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 29-494aa. Protein Length: Partial. Tag Info: Tag-Free. Target Protein Sequence: SKGKLPPGPT PLPFIGNYLQ LNTEQMYNSL MKISERYGPV FTIHLGPRRV VVLCGHDAVR EALVDQAEEF SGRGEQATFD WVFKGYGVVF SNGERAKQLR RFSIATLRDF GVGKRGIEER IQEEAGFLID ALRGTGGANI DPTFFLSRTV...

Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...

Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...

Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...