21 products were found matching "K16343"!
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FKGK11
Item number: TGM-T27327-10mg
Description: FKGK11 is a potent inhibitor of GVIA iPLA2. Target: Others. Smiles: C(C(CCCCC1=CC=CC=C1)=O)(C(F)(F)F)(F)F. References: Paliege A, Roeschel T, Neymeyer H, Seidel S, Kahl T, Daigeler AL, Mutig K, Mrowka R, Ferreri NR, Wilson BS, Himmerkus N, Bleich M, Bachmann S. Group VIA phospholipase A2 is a target for...
| Keywords: | FKGK-11, FKGK 11 |
| Application: | iPLA2 inhibitor |
| CAS | 1071000-98-0 |
| MW: | 280.23 D |
From 98.00€
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FKGK 18
Item number: TGM-T35622-10mg
Description: FKGK 18 is an inhibitor of group VIA (GVIA) calcium-independent phospholipase A2 (iPLA2). It inhibits GVIA iPLA2 by 99.9% at 0.091 mole fraction in a mixed micelle activity assay and is selective for GVIA iPLA2 over GIVA cPLA2 and GV sPLA2 where it shows 80.8 and 36.8% inhibition, respectively. FKGK 18...
| Application: | iPLA2 inhibitor |
| CAS | 1071001-09-6 |
| MW: | 280.28 D |
From 295.00€
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GK187
Item number: TGM-T37221-100mg
Description: GK187 is an inhibitor of Group VIA (GVIA) calcium-independent phospholipase A2 (iPLA2), an enzyme involved in basal cell metabolism. It inhibits GVIA iPLA2 by 99.8% at 0.091 mole fraction in a mixed micelle activity assay and is selective for GVIA iPLA2 over GIVA cPLA2 and GV sPLA2 where it shows less...
| Application: | iPLA2 inhibitor |
| CAS | 1071001-50-7 |
| MW: | 310.26 D |
From 916.00€
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GK563
Item number: TGM-T73527-10mg
Description: GK563, a selective Ca 2+-independent phospholipase A2 (GVIA iPLA2) inhibitor, exhibits a potent IC50 value of 1 nM and demonstrates 22,000-fold greater activity against GVIA iPLA2 compared to GIVA cPLA2. Its efficacy in reducing beta-cell apoptosis triggered by proinflammatory cytokines suggests...
| Application: | iPLA2beta inhibitor |
| CAS | 2351820-19-2 |
| MW: | 246.34 D |
From 233.00€
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Anti-PLA2G6
Item number: CSB-PA202119.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: PLA2G6. Antigen Species: Human
| Keywords: | Anti-PLA2G6, Anti-PLPLA9, Anti-PNPLA9, Anti-GVI PLA2, Anti-CaI-PLA2, Anti-iPLA2-beta, Anti-Palmitoyl-CoA hydrolase,... |
| Application: | ELISA, IHC |
| Host: | Rabbit |
| Species reactivity: | human, mouse, rat |
From 167.00€
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Anti-iPLA2 (Type VI)
Item number: Cay160507-1
Calcium-independent phospholipase A2 (iPLA2) is one of the most recently characterized isoforms in the growing list of the phospholipase A2 enzyme family. iPLA2 has been purified or cloned from CHO cells and mouse P388D1 macrophage-like cells and is the major isoform of phospholipase A2 found in A-10 smooth muscle...
| Keywords: | Anti-PLA2G6, Anti-PLPLA9, Anti-PNPLA9, Anti-PNPLA9, Anti-CaI-PLA2, Anti-GVI PLA2, Anti-CaI-PLA2, Anti-GVI PLA2,... |
| Application: | WB |
| Host: | Rabbit |
| Species reactivity: | human, mouse, bovine, hamster, rat |
431.00€
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FKGK 11
Item number: Cay13179-1
Phospholipase A2 (PLA2) catalyzes the hydrolysis of fatty acids at the sn-2 position of glycerophospholipids, yielding a free fatty acid and a lysophospholipid as products. There are three broad classes of PLA2, secretory (sPLA2), calcium-dependent cytosolic (cPLA2), and calcium-independent cytosolic (iPLA2), that...
| Keywords: | 1,1,1,2,2-pentafluoro-7-phenyl-3-heptanone |
| Application: | iPLA2 inhibitor |
| CAS | 1071000-98-0 |
| MW: | 280.2 D |
From 53.00€
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FKGK 18
Item number: Cay13943-5
FKGK 18 is an inhibitor of group VIA (GVIA) calcium-independent phospholipase A2 (iPLA2). It inhibits GVIA iPLA2 by 99.9% at 0.091 mole fraction in a mixed micelle activity assay and is selective for GVIA iPLA2 over GIVA cPLA2 and GV sPLA2 where it shows 80.8 and 36.8% inhibition, respectively. FKGK 18 inhibits...
| Keywords: | 1,1,1-trifluoro-6-(2-naphthalenyl)-2-hexanone |
| Application: | iPLA2 inhibitor |
| CAS | 1071001-09-6 |
| MW: | 280.3 D |
From 166.00€
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(±)-trans-GK563
Item number: Cay25732-1
trans-(±)-GK563 is a potent beta-lactone inhibitor of group VIA (GVIA) calcium-independent phospholipase A2 (GVIA iPLA2, IC50 = 1 nM). It is selective for GVIA iPLA2 over GVIA cPLA2 (IC50 = 22 µM). trans-(±)-GK563 (1 and 10 µM) inhibits apoptosis induced by IL-1beta and IFN-gamma in INS-1 beta-cells.Formal Name:...
| Keywords: | GK563, (3R,4R)-rel-3-(4-phenylbutyl)-4-propyl-2-oxetanone |
| Application: | iPLA2beta inhibitor |
| CAS | 2351820-19-2 |
| MW: | 246.3 D |
From 128.00€
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Human PLA2G6 / IPLA2 ELISA Kit
Item number: G-HUFI00665.96
| Application: | ELISA |
| Species reactivity: | human |
641.00€
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Anti-PLA2G6
Item number: E-AB-68019.120
The protein encoded by this gene is an A2 phospholipase, a class of enzyme that catalyzes the release of fatty acids from phospholipids. The encoded protein may play a role in phospholipid remodelling, arachidonic acid release, leukotriene and prostaglandin synthesis, fas-mediated apoptosis, and transmembrane ion...
| Keywords: | Anti-PLA2G6, Anti-PNPLA9, Anti-PLPLA9, Anti-CaI-PLA2, Anti-GVI PLA2, Anti-iPLA2-beta, Anti-Palmitoyl-CoA hydrolase,... |
| Application: | WB |
| Host: | Rabbit |
| Species reactivity: | rat |
From 243.00€
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Anti-PLA2G6
Item number: ATA-HPA001171.100
Protein function: Calcium-independent phospholipase involved in phospholipid remodeling with implications in cellular membrane homeostasis, mitochondrial integrity and signal transduction. Hydrolyzes the ester bond of the fatty acyl group attached at sn-1 or sn-2 position of phospholipids (phospholipase A1 and A2...
| Keywords: | Anti-PLA2G6, Anti-PLPLA9, Anti-PNPLA9, Anti-GVI PLA2, Anti-CaI-PLA2, Anti-iPLA2-beta, Anti-Palmitoyl-CoA hydrolase,... |
| Application: | ICC, WB |
| Host: | Rabbit |
| Species reactivity: | human |
From 320.00€
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