72 products were found matching "K15014"!

Protein function: Mediates both influx and efflux of nucleosides across the membrane (equilibrative transporter). It is sensitive (ES) to low concentrations of the inhibitor nitrobenzylmercaptopurine riboside (NBMPR) and is sodium-independent. It has a higher affinity for adenosine. Inhibited by dipyridamole and...

Anti-SLC29A1 antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. SLC29A1 antibody is human specific. SLC29A1 antibody is predicted to not cross-react with other SLC29 proteins. Protein function: Mediates both influx and efflux of nucleosides across the membrane (equilibrative...

0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: Equilibrative nucleoside transporter 1, solute carrier family 29 (nucleoside transporters), member 1, SLC29A1 Protein function: Mediates both influx and efflux of nucleosides across the membrane...

S-(4-Nitrobenzyl)-6-thioinosine is a nucleoside analog that competitively inhibits the equilibrative nucleoside transporter 1 (Kd = 0.1-1.0 nM, IC50s = 4.6 and 3.6 nM in rat and human, respectively). It blocks adenosine flux across the plasma membrane, thereby potentiating the interaction of extracellular adenosine...

This gene is a member of the equilibrative nucleoside transporter family. The gene encodes a transmembrane glycoprotein that localizes to the plasma and mitochondrial membranes and mediates the cellular uptake of nucleosides from the surrounding medium. The protein is categorized as an equilibrative (as opposed to...

Dilazep is an inhibitor of equilibrative nucleoside transporter 1 (ENT1, IC50 = 17.5 nM). It is selective for ENT1 over ENT2 (IC50 = 8,800 nM). Dilazep (0.03 and 0.3 µM) increases adenosine-induced relaxation of, and decreases calcium-induced contractions in isolated guinea pig taenia caeci strips when used at...

Protein function: Mediates both influx and efflux of nucleosides across the membrane (equilibrative transporter). It is sensitive (ES) to low concentrations of the inhibitor nitrobenzylmercaptopurine riboside (NBMPR) and is sodium-independent. It has a higher affinity for adenosine. Inhibited by dipyridamole and...

This gene is a member of the equilibrative nucleoside transporter family. The gene encodes a transmembrane glycoprotein that localizes to the plasma and mitochondrial membranes and mediates the cellular uptake of nucleosides from the surrounding medium. The protein is categorized as an equilibrative (as opposed to...

The human Equilibrative Nucleoside Transporter 1 (hENT1) mediates the cellular uptake of physiologic nucleosides, including adenosine, as well as many anti-cancer drugs including gemcitabine, cytarabine, and decitabine. De ciency of hENT1 can lead to resistance of such drugs, and the abundance of hENT1 protein in...

The human Equilibrative Nucleoside Transporter 1 (hENT1) mediates the cellular uptake of physiologic nucleosides, including adenosine, as well as many anti-cancer drugs including gemcitabine, cytarabine, and decitabine. De ciency of hENT1 can lead to resistance of such drugs, and the abundance of hENT1 protein in...

Protein function: Mediates equilibrative transport of purine, pyrimidine nucleosides and the purine base hypoxanthine. Very less sensitive than SLC29A1 to inhibition by nitrobenzylthioinosine (NBMPR), dipyridamole, dilazep and draflazine. [The UniProt Consortium]