- Search results for K14461
Cookie preferences
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the comfort when using this website, are used for direct advertising or to facilitate interaction with other websites and social networks, are only set with your consent.
Configuration
Technically required
These cookies are necessary for the basic functions of the shop.
"Allow all cookies" cookie
"Decline all cookies" cookie
CSRF token
Cookie preferences
Currency change
Customer-specific caching
FACT-Finder tracking
Individual prices
Selected shop
Session
Comfort functions
These cookies are used to make the shopping experience even more appealing, for example for the recognition of the visitor.
Note
Show the facebook fanpage in the right blod sidebar
Statistics & Tracking
Affiliate program
Conversion and usertracking via Google Tag Manager
Track device being used
16 products were found matching "K14461"!
Close filters
Filter by:
No results were found for the filter!
Item number: Cay16331-25
Ezetimibe is an inhibitor of NPC1-like intracellular cholesterol transporter 1 (NPC1L1, Ki = 220 nM), a cholesterol transporter found in the apical membrane of enterocytes. It reduces cholesterol absorption in hamsters fed a high-cholesterol diet (ED50 = 0.04 mg/kg per day). Ezetimibe (346 nM) also reduces the...
Keywords: | Ezetrol, SCH 58235, (3R,4S)-1,4-fluorophenyl-3-[(3S-3-4-fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)-2-azetidinone |
Application: | NPC1L1 inhibitor, intestinal cholesterol absorption inhibitor |
CAS | 163222-33-1 |
MW: | 409.4 D |
From 98.00€
*
Item number: Cay25044-1
Ezetimibe-d4 is intended for use as an internal standard for the quantification of ezetimibe (Cay-16331) by GC- or LC-MS. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L1) protein, a cholesterol transporter located in the apical membrane of...
Keywords: | Ezetrol-d4,... |
Application: | Internal standard, GC-MS, LC-MS |
CAS | 1093659-89-2 |
MW: | 413.5 D |
642.00€
*
Item number: BPS-27749-2
Ezetimibe is an anti-hyperlipidemic medication which is used to lower cholesterol levels. Specifically, it appears to bind to a critical mediator of cholesterol absorption, the Niemann-Pick C1-Like 1 (NPC1L1) protein on the gastrointestinal tract epithelial cells as well as in hepatocytes.
Keywords: | ezetimibe, Zetia, (3R,4S)-1-(4-fluorophenyl)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)azetidin-2-one, |
Application: | Cholesterol absorption inhibitor, NPC1L1 inhibitor |
MW: | 409.4 D |
From 360.00€
*
Item number: G-CAB10049.100
Application: | WB |
Host: | Rabbit |
Species reactivity: | human |
From 352.00€
*
Item number: Cay34855-1
3'-(2-Fluorophenyl) ezetimibe is an isomer of the cholesterol transport inhibitor ezetimibe (Cay-16331).Formal Name: (3S,4R)-rel-1-(4-fluorophenyl)-3-[(3R)-3-(2-fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)-2-azetidinone. CAS Number: 1798008-25-9. Molecular Formula: C24H21F2NO3. Formula Weight: 409.4. Purity:...
Keywords: | (3S,4R)-rel-1-(4-fluorophenyl)-3-[(3R)-3-(2-fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)-2-azetidinone |
Application: | Ezetimibe isomer |
CAS | 1798008-25-9 |
MW: | 409.4 D |
From 147.00€
*
Item number: NSJ-RQ6664
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Niemann-Pick C1-Like 1 (NPC1L1) is a protein found on the gastrointestinal tract epithelial cells as well as in hepatocytes. The protein encoded by this gene is a multi-pass membrane protein. It contains a conserved N-terminal Niemann-Pick C1 (NPC1) domain and a...
Keywords: | Anti-NPC1L1, Anti-Niemann-Pick C1-like protein 1, Anti-NPC1-like intracellular cholesterol transporter 1, Niemann Pick C1... |
Application: | WB, IF, FC, Direct ELISA |
Host: | Rabbit |
Species reactivity: | human, mouse, rat |
755.00€
*
Item number: VHPS-6284
Primers are provided as a 40 µl solution containing both primers at a final concentration of 50 µM in 10 mM Tris-HCl (pH 7.5), 0.1 mM EDTA. Dilute with water as needed prior to use. This amount is sufficient for 1000 x 20µl PCR reactions assuming a final primer concentration of 0.1 µM. Add cDNA template....
Keywords: | NPC1L1, Niemann-Pick C1-like protein 1 |
Application: | RNA quantification |
43.00€
*
Item number: VMPS-4302
Primers are provided as a 40 µl solution containing both primers at a final concentration of 50 µM in 10 mM Tris-HCl (pH 7.5), 0.1 mM EDTA. Dilute with water as needed prior to use. This amount is sufficient for 1000 x 20µl PCR reactions assuming a final primer concentration of 0.1 µM. Add cDNA template....
Keywords: | Npc1l1, Niemann-Pick C1-like protein 1 |
Application: | RNA quantification |
43.00€
*
Item number: 039084-APC.200
The protein encoded by this gene is a multi-pass membrane protein. It contains a conserved N-terminal Niemann-Pick C1 (NPC1) domain and a putative sterol-sensing domain (SSD) which includes a YQRL motif functioning as a plasma membrane to trans-Golgi network transport signal in other proteins. This protein takes up...
Keywords: | Anti-NPC1L1, Anti-Niemann-Pick C1-like protein 1 |
Application: | FLISA, WB |
Host: | Rabbit |
Species reactivity: | human |
993.00€
*
Item number: 039084-Biotin.200
The protein encoded by this gene is a multi-pass membrane protein. It contains a conserved N-terminal Niemann-Pick C1 (NPC1) domain and a putative sterol-sensing domain (SSD) which includes a YQRL motif functioning as a plasma membrane to trans-Golgi network transport signal in other proteins. This protein takes up...
Keywords: | Anti-NPC1L1, Anti-Niemann-Pick C1-like protein 1 |
Application: | ELISA, WB |
Host: | Rabbit |
Species reactivity: | human |
993.00€
*
Item number: 039084-FITC.200
The protein encoded by this gene is a multi-pass membrane protein. It contains a conserved N-terminal Niemann-Pick C1 (NPC1) domain and a putative sterol-sensing domain (SSD) which includes a YQRL motif functioning as a plasma membrane to trans-Golgi network transport signal in other proteins. This protein takes up...
Keywords: | Anti-NPC1L1, Anti-Niemann-Pick C1-like protein 1 |
Application: | FLISA, WB |
Host: | Rabbit |
Species reactivity: | human |
993.00€
*
Item number: 039084-HRP.200
The protein encoded by this gene is a multi-pass membrane protein. It contains a conserved N-terminal Niemann-Pick C1 (NPC1) domain and a putative sterol-sensing domain (SSD) which includes a YQRL motif functioning as a plasma membrane to trans-Golgi network transport signal in other proteins. This protein takes up...
Keywords: | Anti-NPC1L1, Anti-Niemann-Pick C1-like protein 1 |
Application: | ELISA, WB |
Host: | Rabbit |
Species reactivity: | human |
993.00€
*