42 products were found matching "K13869"!

Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml. SLC7A11 antibody detects Solute carrier family 7 member 11, a cystine/glutamate antiporter subunit that mediates cellular cystine uptake in exchange for intracellular glutamate export. SLC7A11, also known as xCT, forms part of the system Xc-...

Imidazole ketone erastin is an inducer of ferroptosis. It inhibits glutamate release in human CCF-STTG1 astrocytoma cells (IC50 = 30 nM), indicating inhibition of the system xc- cystine/glutamate transporter. Imidazole ketone erastin increases production of lipid reactive oxygen species (ROS) in SUDHL6 diffuse large...

Erastin2 is a ferroptosis inducer and an inhibitor of the system xc- cystine/glutamate transporter. It inhibits glutamate release in CCF-STTG1 cells (IC50 = 0.0035 µM). It induces cell death in HAP1 cells when used at a concentration of 5 µM, an effect that can be blocked by the ferroptosis inhibitor ferrostatin-1...

Protein function: Sodium-independent, high-affinity exchange of anionic amino acids with high specificity for anionic form of cystine and glutamate. [The UniProt Consortium]

This affinity purified antibody is directed against human xCT. This product was affinity purified from monospecific antiserum by immunoaffinity purification. Blast analysis of the sequence of the immunogen shows 100% identity with human and orangutan, and 88% identity to mouse. Protein function: Sodium-independent,...

This affinity purified antibody is directed against human xCT. This product was affinity purified from monospecific antiserum by immunoaffinity purification. Blast analysis of the sequence of the immunogen shows 100% identity with human and orangutan, and 88% identity to mouse. Protein function: Sodium-independent,...

0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: Solute carrier family 7 (cationic amino acid transporter, y+ system) member 11, SLC7A11 Protein function: Sodium-independent, high-affinity exchange of anionic amino acids with high specificity...

Protein function: Sodium-independent, high-affinity exchange of anionic amino acids with high specificity for anionic form of cystine and glutamate. [The UniProt Consortium]

This gene encodes a member of a heteromeric, sodium-independent, anionic amino acid transport system that is highly specific for cysteine and glutamate. In this system, designated Xc(-), the anionic form of cysteine is transported in exchange for glutamate. This protein has been identified as the predominant...

FA16 is a ferroptosis inducer and an inhibitor of the system xc- cystine/glutamate transporter. It reduces the viability of various cancer cell lines, including HT-1080 fibrosarcoma and A375 melanoma cells (IC50s = 1.26 and 2.31 µM, respectively), 786-O renal cell carcinoma cells (IC50 = 0.7 µM), and MDA-MB-231...

Recombinant Human SLC7A11 Protein with C-terminal human Fc tag. SLC7A11(Lys67-Gly74) (Leu151-Cys158) (Lys215-Thr233) (Thr219-Leu317) (Asp386-Ser387) (Ser445-Pro447) hFc(Glu99-Ala330), Protein function: Sodium-independent, high-affinity exchange of anionic amino acids with high specificity for anionic form of cystine...