25 products were found matching "K13780"!

In 1X PBS, pH 7.4, with 0.09% sodium azide. Large neutral amino acids transporter small subunit 1 / LAT1 / SLC7A5 is a sodium-independent, high-affinity transport of large neutral amino acids such as phenylalanine, tyrosine, leucine, arginine and tryptophan, when associated with SLC3A2/4F2hc. Involved in cellular...

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human LAT1. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human LAT1. Next,...

The L-type amino acid transporters (LATs) are Na+-dependent neutral amino acid transporters. They include four members in two sub-families, with LAT1 and LAT2 belonging to solute carrier (SLC) family 7 and LAT3 and LAT4 being members of SLC43. LAT1 is overexpressed in many tumors and contributes to ribosome...

JPH203 is an inhibitor of L-type amino acid transporter 1 (LAT1, IC50 = 0.14 µM for 14C-leucine uptake in S2 cells expressing the human transporter). It is selective for LAT1 over LAT2 (IC50 = >10 µM). JPH203 inhibits 14C-leucine uptake by, and growth of, HT-29 cells (IC50s = 0.06 and 4.1 µM, respectively). It...

JPH203 is an inhibitor of L-type amino acid transporter 1 (LAT1, IC50 = 0.14 µM for 14C-leucine uptake in S2 cells expressing the human transporter). It is selective for LAT1 over LAT2 (IC50 = >10 µM). JPH203 inhibits 14C-leucine uptake by, and growth of, HT-29 cells (IC50s = 0.06 and 4.1 µM, respectively). It...

Protein function: Sodium-independent, high-affinity transport of large neutral amino acids such as phenylalanine, tyrosine, leucine, arginine and tryptophan, when associated with SLC3A2/4F2hc. Involved in cellular amino acid uptake. Acts as an amino acid exchanger. Involved in the transport of L-DOPA across the...

Protein function: Sodium-independent, high-affinity transport of large neutral amino acids such as phenylalanine, tyrosine, leucine, arginine and tryptophan, when associated with SLC3A2/4F2hc. Involved in cellular amino acid uptake. Acts as an amino acid exchanger. Involved in the transport of L-DOPA across the...

0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: L-type amino acid transporter 1, SLC7A5, solute carrier family 7 (cationic amino acid transporter, y+ system), member 5 Protein function: Sodium-independent, high-affinity transport of large...

Concentration: 0.25 mg/ml. Formulation: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol. Solute carrier family 7 member 5 (also known as large neutral amino acids transporter small subunit 1) is a protein encoded by the SLC7A5 gene in human. SLC7A5 plays a role in neuronal cell proliferation, is...

Protein function: The heterodimer with SLC3A2 functions as sodium- independent, high-affinity transporter that mediates uptake of large neutral amino acids such as phenylalanine, tyrosine, L-DOPA, leucine, histidine, methionine and tryptophan (PubMed:9751058, PubMed:10049700, PubMed:11557028, PubMed:10391915,...

Protein function: The heterodimer with SLC3A2 functions as sodium-independent, high-affinity transporter that mediates uptake of large neutral amino acids such as phenylalanine, tyrosine, L-DOPA, leucine, histidine, methionine and tryptophan (PubMed:9751058, PubMed:10049700, PubMed:11557028, PubMed:10391915,...