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Mouse PDE1C (Phosphodiesterase 1C, Calmodulin Dependent) ELISA Kit
Mouse PDE1C (Phosphodiesterase 1C, Calmodulin Dependent)...

Item number: ELK-ELK7185.48

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse PDE1C. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse PDE1C. Next,...
Keywords: Cam-PDE 1C, Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C
Application: ELISA
Species reactivity: mouse
365.00€ * From 328.50€ *
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Human PDE1A (Phosphodiesterase 1A, Calmodulin Dependent) ELISA Kit
Human PDE1A (Phosphodiesterase 1A, Calmodulin Dependent)...

Item number: ELK-ELK4781.48

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human PDE1A. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human PDE1A. Next,...
Keywords: hCam-1, Cam-PDE 1A, 61 kDa Cam-PDE, Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide...
Application: ELISA
Species reactivity: human
365.00€ * From 328.50€ *
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8-Methoxymethyl-3-isobutyl-1-methylxanthine
8-Methoxymethyl-3-isobutyl-1-methylxanthine

Item number: Cay39151-1

8-Methoxymethyl-3-isobutyl-1-methylxanthine is an inhibitor of phosphodiesterase 1 (PDE1, IC50 = 5 µM) and a derivative of IBMX (Cay-13347). It is selective for PDE1 over PDE2, PDE3, and PDE4 but also inhibits PDE5 (IC50s = 37, >400, >400, and 2 µM, respectively). 8-Methoxymethyl-3-isobutyl-1-methylxanthine (30 µM)...
Keywords: 8-MeOMeMIX, 8-methoxymethyl IBMX, 8-MM-IBMX, MMPX,...
Application: PDE1 inhibitor
CAS 78033-08-6
MW: 266.3 D
From 62.00€ *
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Vinpocetine
Vinpocetine

Item number: AG-CN2-0454-M020

White to slightly yellow crystalline powder. Soluble in DMSO, dichloromethane, acetone or 100% ethanol. Insoluble in water. Selective Ca2+-calmodulin dependent cGMP-phosphodiesterase (PDE1) inhibitor. Shows vasorelaxant activity, Neuroprotective agent, Selectively inhibits voltage-sensitive 2+ channels, Potent...
Keywords: (3alpha,16alpha)-Eburnamenine-14-carboxylic acid ethyl ester, Ethyl apovincaminate, RGH-4405, TCV 3B, AY 27255
Application: PDE1 inhibitor
CAS 42971-09-5
MW: 350,5 D
39.00€ * From 35.10€ *
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PDE1B, active human recombinant protein
PDE1B, active human recombinant protein

Item number: BPS-60011

Active human PDE1B (GenBank Accession No. NM_000924), full length with N-terminal GST tag, MW= 87 kDa, expressed in a Baculovirus infected Sf9 cell expression system.
Keywords: PDES1B, Cam-PDE 1B, 63 kDa Cam-PDE, Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide...
Application: Enzyme kinetics, inhibitor screening
MW: 87 kD
672.00€ *
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PDE1A Assay Kit
PDE1A Assay Kit

Item number: BPS-60310

Phosphodiesterases (PDEs) play an important role in dynamic regulation of cAMP and cGMP signaling. PDE1A1 is a calmodulin-dependent PDE and expressed in lung and heart. PDE1A1 is believed to regulate vascular smooth muscle contraction and may play a role in sperm function. The PDE1A Assay Kit is designed for...
Keywords: inhibitor screening, assay kit, PDE1A,
Application: Enzyme kinetics, inhibitor screening, HTS
Species reactivity: human
599.00€ *
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PDE1B assay kit
PDE1B assay kit

Item number: BPS-60311

The PDE1B Assay Kit is designed for identification of PDE1B inhibitors using fluorescence polarization. The assay is based on the binding of a fluorescent nucleotide monophosphate generated by PDE1B to the binding agent. PDE1B is a calcium-dependent cyclic nucleotide phosphodiesterase that is highly expressed in the...
Keywords: inhibitor screening, assay kit, PDE1B,
Application: PDE1B assays, inhibitor screening, FP
599.00€ *
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Vinpocetine
Vinpocetine

Item number: Cay19578-100

Vinpocetine is a semisynthetic alkaloid commonly used as an inhibitor of phosphodiesterase 1 (PDE1), blocking the hydrolysis of both cAMP and cGMP (Ki = 14 µM). In addition to its use as a selective PDE1 inhibitor in basic research, vinpocetine has diverse cerebral and neurological effects in vivo. Vinpocetine also...
Keywords: Apovincaminic Acid ethyl ester, AY 27255, RGH-4405, (3alpha,16alpha)-eburnamenine-14-carboxylic acid, ethyl ester
Application: Neuroprotectant, PDE1 inhibitor
CAS 42971-09-5
MW: 350.5 D
From 68.00€ *
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W-5 . hydrochloride
W-5 . hydrochloride

Item number: AG-CR1-0003-M005

Calmodulin antagonist, Cell proliferation inhibitor, Ca2????regulated phosphodiesterase (PDE I) inhibitor, Myosin light chain kinase (MLCK) inhibitor.
Keywords: N-(6-Aminohexyl)-1-naphthalenesulfonamide . HCl
Application: Calmodulin antagonist, Cell proliferation inhibitor
CAS 61714-25-8
MW: 306,4 D
55.00€ * From 49.50€ *
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ITI214
ITI214

Item number: Cay30376-5

ITI214 is an inhibitor of phosphodiesterase 1 (PDE1, Ki = 0.058 nM). It is selective for PDE1 over PDE2A, -3B, -4A, -5A, -6, -7B, -8A, -9A, -10A, and -11A (Kis = 0.16-18 µM). ITI214 (3 and 6 mg/kg) enhances novel object recognition in rats. It increases prefrontal cortex cAMP and cGMP levels in mice when...
Keywords: (6aR,9aS)-2-[[4-(6-fluoro-2-pyridinyl)phenyl]methyl]-5,6a,7,8,9,9a-hexahydro-5-methyl-3-(phenylamino)-cyclopent[4,5]imidaz...
Application: PDE1 inhibitor
CAS 1642303-38-5
MW: 605.6 D
From 109.00€ *
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Anti-PDE1A
Anti-PDE1A

Item number: ARG10791.50

Protein function: Cyclic nucleotide phosphodiesterase with a dual- specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. Has a higher affinity for cGMP than for cAMP. [The UniProt Consortium]
Keywords: Anti-Pde1a, Anti-Cam-PDE 1A, EC=3.1.4.17, Anti-61 kDa Cam-PDE, Anti-Calcium/calmodulin-dependent 3',5'-cyclic nucleotide...
Application: IF, ELISA, ICC, IF, IHC, IP, WB, DB
Host: Rabbit
Species reactivity: human, mouse, rat
576.00€ *
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Anti-PDE1B
Anti-PDE1B

Item number: ARG10792.50

Protein function: Cyclic nucleotide phosphodiesterase with a dual- specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. Has a preference for cGMP as a substrate. [The UniProt Consortium]
Keywords: Anti-PDE1B, Anti-PDE1B1, Anti-Cam-PDE 1B, EC=3.1.4.17, Anti-63 kDa Cam-PDE, Anti-Calcium/calmodulin-dependent 3',5'-cyclic...
Application: IF, ELISA, ICC, IF, IHC (paraffin), IP, WB, DB
Host: Rabbit
Species reactivity: human, mouse, rat
576.00€ *
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