91 products were found matching "K13525"!
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Anti-VCP
Item number: ABS-KC-1868.100
Protein function: Necessary for the fragmentation of Golgi stacks during mitosis and for their reassembly after mitosis. Involved in the formation of the transitional endoplasmic reticulum (tER). The transfer of membranes from the endoplasmic reticulum to the Golgi apparatus occurs via 50-70 nm transition vesicles...
| Keywords: | Anti-Transitional endoplasmic reticulum ATPase, Anti-TER ATPase, Anti-15S Mg(2+)-ATPase p97 subunit,... |
| Host: | Mouse |
| Species reactivity: | human, mouse |
From 232.00€
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Anti-VCP
Item number: ABS-KC-1869.100
Protein function: Necessary for the fragmentation of Golgi stacks during mitosis and for their reassembly after mitosis. Involved in the formation of the transitional endoplasmic reticulum (tER). The transfer of membranes from the endoplasmic reticulum to the Golgi apparatus occurs via 50-70 nm transition vesicles...
| Keywords: | Anti-Transitional endoplasmic reticulum ATPase, Anti-TER ATPase, Anti-15S Mg(2+)-ATPase p97 subunit,... |
| Host: | Mouse |
| Species reactivity: | human, mouse |
From 232.00€
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Anti-VCP
Item number: ABS-KC-1870.100
Protein function: Necessary for the fragmentation of Golgi stacks during mitosis and for their reassembly after mitosis. Involved in the formation of the transitional endoplasmic reticulum (tER). The transfer of membranes from the endoplasmic reticulum to the Golgi apparatus occurs via 50-70 nm transition vesicles...
| Keywords: | Anti-Transitional endoplasmic reticulum ATPase, Anti-TER ATPase, Anti-15S Mg(2+)-ATPase p97 subunit,... |
| Host: | Mouse |
| Species reactivity: | human, mouse |
From 232.00€
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Anti-VCP
Item number: ABS-KC-2509.100
Protein function: Necessary for the fragmentation of Golgi stacks during mitosis and for their reassembly after mitosis. Involved in the formation of the transitional endoplasmic reticulum (tER). The transfer of membranes from the endoplasmic reticulum to the Golgi apparatus occurs via 50-70 nm transition vesicles...
| Keywords: | Anti-Transitional endoplasmic reticulum ATPase, Anti-TER ATPase, Anti-15S Mg(2+)-ATPase p97 subunit,... |
| Application: | IHC |
| Host: | Mouse |
| Species reactivity: | human |
From 206.00€
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Anti-VCP
Item number: A300-589A
Protein function: Necessary for the fragmentation of Golgi stacks during mitosis and for their reassembly after mitosis. Involved in the formation of the transitional endoplasmic reticulum (tER). The transfer of membranes from the endoplasmic reticulum to the Golgi apparatus occurs via 50-70 nm transition vesicles...
| Keywords: | Anti-VCP, Anti-TER ATPase, EC=3.6.4.6, Anti-Valosin-containing protein, Anti-15S Mg(2+)-ATPase p97 subunit,... |
| Application: | WB, IP |
| Host: | Rabbit |
| Species reactivity: | human, mouse |
From 178.00€
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DBEQ
Item number: TGM-T1969-100mg
Description: DBEQ (JRF 12) is a selective, potent, reversible, and ATP-competitive p97 inhibitor. Target: Autophagy, Apoptosis, p97. Smiles: C(Nc1nc(NCc2ccccc2)c2ccccc2n1)c1ccccc1. References: Chou TF, et al. Proc Natl Acad Sci U S A, 2011, 108(12), 4834-4839.
| Keywords: | JRF 12 |
| Application: | ATPase p97 inhibitor |
| CAS | 177355-84-9 |
| MW: | 340.42 D |
From 54.00€
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NMS-873
Item number: TGM-T1853-100mg
Description: NMS-873 is a potent and selective allosteric inhibitor of VCP/p97. Target: p97. Smiles: Cc1cc(OCc2nnc(SC3CCCC3)n2-c2cccnc2)ccc1-c1ccc(cc1)S(C)(=O)=O. References: Magnaghi P, et al. Nat Chem Biol. 2013, 9(9), 548-556.
| Application: | VCP inhibitor |
| CAS | 1418013-75-8 |
| MW: | 520.67 D |
From 40.00€
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CB-5083
Item number: TGM-T6796-100mg
Description: CB-5083 is a potent, selective, and orally bioavailable p97 AAA ATPase inhibitor ( IC50=11 nM). Target: p97. Smiles: Cc1cc2c(cccc2n1-c1nc2CCOCc2c(NCc2ccccc2)n1)C(N)=O. References: Zhou HJ, et al. J Med Chem. 2015, 58(24), 9480-9497.
| Keywords: | CB5083, CB 5083 |
| Application: | p97 inhibitor |
| CAS | 1542705-92-9 |
| MW: | 413.47 D |
From 40.00€
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CB-5083
Item number: Cay19311-1
CB-5083 is an orally bioavailable inhibitor of p97 (IC50 = 11 nM), a transitional endoplasmic reticulum ATPase also known as valosin-containing protein (VCP). It disrupts cellular protein homeostasis and demonstrates anti-tumor activity in hematological and solid tumor models. CB-5083 causes accumulation of...
| Keywords: | 1-[7,8-dihydro-4-[(phenylmethyl)amino]-5H-pyrano[4,3-d]pyrimidin-2-yl]-2-methyl-1H-indole-4-carboxamide |
| Application: | p97 inhibitor |
| CAS | 1542705-92-9 |
| MW: | 413.5 D |
From 61.00€
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ML240
Item number: TGM-T3535-100mg
Description: ML240 is a selective, ATP-competitive p97 inhibitor. Target: p97. Smiles: COc1cccc2c(NCc3ccccc3)nc(nc12)-n1c(N)nc2ccccc12. References: Tsui-Fen Chou et al. Specific Inhibition of p97/VCP ATPase and Kinetic Analysis Demonstrate Interaction between D1 and D2 ATPase domains.
| Application: | p97 ATPase inhibitor |
| CAS | 1346527-98-7 |
| MW: | 396.44 D |
From 33.00€
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KUS121
Item number: TGM-T36570-10mg
Description: KUS121 is a valosin-containing protein (VCP) modulator that inhibits VCP ATPase activity (IC50= 330 nM).1It inhibits cell death, ATP depletion, and upregulation of C/EBP-homologous protein (CHOP) induced by tunicamycin, an inducer of ER stress, in HeLa cells when used at concentrations of 20, 50, and 50...
| Application: | VCP modulator |
| CAS | 1357164-52-3 |
| MW: | 459.45 D |
From 264.00€
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ML241 hydrochloride
Item number: TGM-T4684-100mg
Description: ML241 is a potent and selective inhibitors of p97 ATPase.ML241 inhibits degradation of a p97-dependent but not a p97-independent proteasome substrate in a dual-reporter cell line. ML241 may be a novel agent for the chemotherapy of cancer, and provide a rationale for developing pathway-specific p97...
| Application: | Selective ATPase p97 inhibitor |
| CAS | 2070015-13-1 |
| MW: | 408.92 D |
From 46.00€
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