315 products were found matching "K13375"!

This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically...

Transforming growth factor-beta (TGF-beta) superfamily members are critical regulators of cell proliferation and differentiation, developmental patterning and morphogenesis, and disease pathogenesis. TGF-beta elicits signaling through three cell surface receptors: type I (RI), type II (RII), and type III (RIII)....

Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml. The TGFB1 antibody targets Transforming growth factor beta-1, a multifunctional cytokine encoded by the TGFB1 gene that regulates cell growth, differentiation, immune response, and extracellular matrix production. As a member of the TGF-beta...

Protein function: Multifunctional protein that controls proliferation, differentiation and other functions in many cell types. Many cells synthesize TGFB1 and have specific receptors for it. It positively and negatively regulates many other growth factors. It plays an important role in bone remodeling as it is a...

Protein function: Multifunctional protein that controls proliferation, differentiation and other functions in many cell types. Many cells synthesize TGFB1 and have specific receptors for it. It positively and negatively regulates many other growth factors. It plays an important role in bone remodeling as it is a...

Protein function: Transforming growth factor beta-1 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains, which constitute the regulatory and active subunit of TGF-beta-1, respectively. [The UniProt Consortium]

Protein function: Multifunctional protein that controls proliferation, differentiation and other functions in many cell types. Many cells synthesize TGFB1 and have specific receptors for it. It positively and negatively regulates many other growth factors. It plays an important role in bone remodeling as it is a...

TGF-beta1 (transforming growth factor beta 1) is one of three closely related mammalian members of the large TGF-beta1 superfamily that share a characteristic cystine knot structure. TGF-beta1, -2 and -3 are highly pleiotropic cytokines that act as cellular switches to regulate processes such as immune function,...

Transforming growth factor beta 1 (TGFbeta1) is the prototype of a growing superfamily of peptide growth factors and plays a prominent role in a variety of cellular processes, including cell-cycle progression, cell differentiation, reproductive function, development, motility, adhesion, neuronal growth, bone...

TGF-beta1 (transforming growth factor beta 1) is one of three closely related mammalian members of the large TGF-beta1 superfamily that share a characteristic cystine knot structure. TGF-beta1, -2 and -3 are highly pleiotropic cytokines that act as cellular switches to regulate processes such as immune function,...

GARP&Latent TGF Beta is a complex found on surface of many types of cells. In Tregs, GARP is involved in TCR-mediated activation of Latent TGF-beta and thus promoting secretion and activation of TGF-beta. Integrin alphavbeta8 on the surface of immune cells and other cells recognizes RGD in LAP, resulting in the...

Latent TGF beta 1 cDNA encodes a 390 amino acid precursor that contains a 29 aa signal peptide and a 361 aa proprotein. A furin-like convertase processes the proprotein to generate an N-terminal 249 aa latency-associated peptide (LAP) and a C-terminal 112 aa mature TGF- beta 1. Disulfide-linked homodimers of LAP and...