- Search results for K13097
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16 products were found matching "K13097"!
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Item number: Cay31453-5
Bobcat 339 is a cytosine derivative that was originally found to be an inhibitor of ten-eleven translocation methylcytosine dioxygenase 1 (TET1) and TET2 (IC50s = 33 and 73 µM, respectively, in cell-free assays). However, it was found that the TET inhibitory activity was due to residual copper in the Bobcat 339...
Keywords: | 4-amino-1-[1,1'-biphenyl]-3-yl-5-chloro-2(1H)-pyrimidinone |
Application: | TET1 / TET2 inhibitor |
CAS | 2280037-51-4 |
MW: | 297.7 D |
From 84.00€
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Item number: BPS-50651
The TET1 Chemiluminescent Assay Kit is designed to measure TET1 activity for screening and profiling applications. TET1 belongs to the Ten Eleven Translocation (TET) family proteins that catalyze 5-methylcytosine oxidation and generate 5-methylcytosine derivatives, including 5-hydroxymethylcytosine. TET1 may repress...
Keywords: | Ten-eleven translocation 1 protein (TET1), methylcytosine dioxygenase TET1, Leukemiaassociated protein with a CXXC domain,... |
Application: | Enzyme kinetics, HTS |
Species reactivity: | human |
1,065.00€
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Item number: ARG55403.50
Protein function: Dioxygenase that catalyzes the conversion of the modified genomic base 5-methylcytosine (5mC) into 5- hydroxymethylcytosine (5hmC) and plays a key role in active DNA demethylation. Also mediates subsequent conversion of 5hmC into 5- formylcytosine (5fC), and conversion of 5fC to 5-carboxylcytosine...
Keywords: | Anti-TET1, Anti-CXXC6, Anti-Methylcytosine dioxygenase TET1, Anti-CXXC-type zinc finger protein 6, Anti-Ten-eleven... |
Application: | WB |
Host: | Rabbit |
Species reactivity: | human, mouse, rat |
520.00€
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Item number: BPS-50161-1
Human Ten-eleven translocation 1 protein (TET1), methylcytosine dioxygenase TET1, Leukemiaassociated protein with a CXXC domain, CXXC-type zinc finger protein 6, GenBank Accession # NM_030625, a.a. 1418-2136(end) with N-terminal FLAG-tag, MW = 80 kDa, expressed in Sf9 cells via a baculovirus expression system.
Keywords: | CXXC6, Methylcytosine dioxygenase TET1, CXXC-type zinc finger protein 6, Ten-eleven translocation 1 gene protein,... |
Application: | Enzyme kinetics, inhibitor screening, selectivity profiling |
Expressed in: | insect cells |
Origin: | human |
MW: | 80 kD |
From 385.00€
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Item number: E-AB-60317.120
DNA methylation is an epigenetic mechanism that is important for controlling gene expression. The protein encoded by this gene is a demethylase that belongs to the TET (ten-eleven translocation) family. Members of the TET protein family play a role in the DNA methylation process and gene activation. Protein...
Keywords: | Anti-CXXC6, Anti-Methylcytosine dioxygenase TET1, Anti-CXXC-type zinc finger protein 6, Anti-Ten-eleven translocation 1... |
Application: | WB |
Host: | Rabbit |
Species reactivity: | human, mouse, rat |
From 198.00€
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Item number: NSJ-RQ5678
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Ten-eleven translocation methylcytosine dioxygenase 1 (TET1) is a member of the TET family of enzymes, in humans it is encoded by the TET1 gene. DNA methylation is an epigenetic mechanism that is important for controlling gene expression. The protein encoded by...
Keywords: | Anti-CXXC6, Anti-CXXC-type zinc finger protein 6, Anti-Methylcytosine dioxygenase TET1, Anti-Ten-eleven translocation 1... |
Application: | WB, IHC (paraffin), IF, FC, Direct ELISA |
Host: | Rabbit |
Species reactivity: | human, monkey |
755.00€
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Item number: G-CAB1506.100
Application: | IP, WB |
Host: | Rabbit |
Species reactivity: | human, mouse, rat |
From 352.00€
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Item number: ATA-HPA019032.100
Protein function: Dioxygenase that catalyzes the conversion of the modified genomic base 5-methylcytosine (5mC) into 5-hydroxymethylcytosine (5hmC) and plays a key role in active DNA demethylation. Also mediates subsequent conversion of 5hmC into 5-formylcytosine (5fC), and conversion of 5fC to 5-carboxylcytosine...
Keywords: | Anti-CXXC6, Anti-Methylcytosine dioxygenase TET1, Anti-CXXC-type zinc finger protein 6, Anti-Ten-eleven translocation 1... |
Application: | ICC, IHC |
Host: | Rabbit |
Species reactivity: | human |
From 300.00€
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Item number: ATA-HPA057273.100
Protein function: Dioxygenase that catalyzes the conversion of the modified genomic base 5-methylcytosine (5mC) into 5-hydroxymethylcytosine (5hmC) and plays a key role in active DNA demethylation. Also mediates subsequent conversion of 5hmC into 5-formylcytosine (5fC), and conversion of 5fC to 5-carboxylcytosine...
Keywords: | Anti-CXXC6, Anti-Methylcytosine dioxygenase TET1, Anti-CXXC-type zinc finger protein 6, Anti-Ten-eleven translocation 1... |
Application: | ICC |
Host: | Rabbit |
Species reactivity: | human |
From 300.00€
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Item number: E-AB-93259.120
Enables methylcytosine dioxygenase activity. Involved in several processes, including dendrite morphogenesis, inner cell mass cell differentiation, and protein O-linked glycosylation. Acts upstream of or within DNA demethylation, regulation of DNA methylation, and regulation of genetic imprinting. Located in...
Keywords: | Tet1, Cxxc6, Methylcytosine dioxygenase TET1, CXXC-type zinc finger protein 6, Ten-eleven translocation 1 gene protein... |
Application: | IHC |
Host: | Rabbit |
Species reactivity: | human, mouse, rat |
From 198.00€
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Item number: 009-001-U13
Recombinant human TET1 (1598-end) was expressed by baculovirus in Sf9 insect cells using an N-Terminal Glutathione-S-Transferase fusion protein. The purity was determined to be >90% by densitometry. Protein function: Dioxygenase that catalyzes the conversion of the modified genomic base 5-methylcytosine (5mC) into...
Keywords: | TET1, CXXC6, CXXC-type zinc finger protein 6, Methylcytosine dioxygenase TET1, Ten-eleven translocation 1 gene protein,... |
Application: | WB |
Expressed in: | Human |
958.00€
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Item number: 009-001-U13S
Recombinant human TET1 (1598-end) was expressed by baculovirus in Sf9 insect cells using an N-Terminal Glutathione-S-Transferase fusion protein. The purity was determined to be >90% by densitometry. Protein function: Dioxygenase that catalyzes the conversion of the modified genomic base 5-methylcytosine (5mC) into...
Keywords: | TET1, CXXC6, CXXC-type zinc finger protein 6, Methylcytosine dioxygenase TET1, Ten-eleven translocation 1 gene protein,... |
Application: | WB |
Expressed in: | Human |
468.00€
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