61 products were found matching "K12647"!

Active, human MDA5 (AA 299-1025) protein expressed and purified from Baculovirus. The enzyme has been thoroughly validated with the Transcreener ADP Assay Kit. For specific activity, please refer to the Certificate of Analysis for each individual enzyme lot. Purity is >90% in a composition of 20 mM HEPES, 150 mM...

The Enzolution(R) MDA5 ATPase Assay System is intended for use with the Transcreener(R) ADP2 Assay Kits to measure the RNA-dependent ATPase activity of MDA5. MDA5 (melanoma differentiation-associated gene 5) is a member of the RLR (RIG-I-like receptors) family of immune sensors that bind double-stranded RNA (dsRNA)...

The Enzolution(R) MDA5 ATPase Assay System is intended for use with the Transcreener(R) ADP2 Assay Kits to measure the RNA-dependent ATPase activity of MDA5. MDA5 (melanoma differentiation-associated gene 5) is a member of the RLR (RIG-I-like receptors) family of immune sensors that bind double-stranded RNA (dsRNA)...

The Enzolution(R) MDA5 ATPase Assay System is intended for use with the Transcreener(R) ADP2 Assay Kits to measure the RNA-dependent ATPase activity of MDA5. MDA5 (melanoma differentiation-associated gene 5) is a member of the RLR (RIG-I-like receptors) family of immune sensors that bind double-stranded RNA (dsRNA)...

Protein function: Innate immune receptor which acts as a cytoplasmic sensor of viral nucleic acids and plays a major role in sensing viral infection and in the activation of a cascade of antiviral responses including the induction of type I interferons and proinflammatory cytokines. Its ligands include mRNA lacking...

Anti-MDA5 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with MDA5 from other sources has not been determined. Protein function: Innate immune receptor which acts as a cytoplasmic sensor of viral nucleic acids and plays a major role in sensing viral...

Anti-MDA5 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with MDA5 from other sources has not been determined. Protein function: Innate immune receptor which acts as a cytoplasmic sensor of viral nucleic acids and plays a major role in sensing viral...

0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: Melanoma differentiation associated protein-5, IFIH1, interferon induced with helicase C domain 1 Protein function: Innate immune receptor which acts as a cytoplasmic sensor of viral nucleic...

Protein function: Innate immune receptor which acts as a cytoplasmic sensor of viral nucleic acids and plays a major role in sensing viral infection and in the activation of a cascade of antiviral responses including the induction of type I interferons and proinflammatory cytokines. Its ligands include mRNA lacking...

Polyclonal Antibody. Recognizes mouse MDA5. Source: Rabbit. Applications: IHC, WB. Liquid. In PBS containing 0.02% sodium azide. RIG-I and MDA5 are highly conserved helicases involved in the innate immune response to virus. MDA5, upon interaction with intracellular dsRNA (produced during viral replication), triggers...

Protein function: Innate immune receptor which acts as a cytoplasmic sensor of viral nucleic acids and plays a major role in sensing viral infection and in the activation of a cascade of antiviral responses including the induction of type I interferons and proinflammatory cytokines. Its ligands include mRNA lacking...