37 products were found matching "K12350"!

Description: Acid sphingomyelinase/SMPD1 Protein, Human, Recombinant (His) is expressed in Baculovirus-Insect Cells. The accession number is P17405-1.

Protein function: Converts sphingomyelin to ceramide (PubMed:1840600, PubMed:18815062, PubMed:27659707, PubMed:25920558). Also has phospholipase C activities toward 1,2-diacylglycerolphosphocholine and 1,2-diacylglycerolphosphoglycerol. [The UniProt Consortium]

1-Aminodecylidene bis-phosphonic acid is a potent inhibitor of acid sphingomyelinase (IC50 = 20 nM). It is selective for acid sphingomyelinase over neutral sphingomyelinase (IC50 = >100 µM). 1-Aminodecylidene bis-phosphonic acid completely inhibits apoptosis induced by dexamethasone (Cay-11015) in HepG2 cells.Formal...

Protein function: Converts sphingomyelin to ceramide (PubMed:1840600, PubMed:18815062, PubMed:27659707, PubMed:25920558). Also has phospholipase C activities toward 1,2-diacylglycerolphosphocholine and 1,2-diacylglycerolphosphoglycerol. [The UniProt Consortium]

Protein function: Converts sphingomyelin to ceramide (PubMed:1840600, PubMed:18815062, PubMed:27659707, PubMed:25920558). Also has phospholipase C activities toward 1,2-diacylglycerolphosphocholine and 1,2-diacylglycerolphosphoglycerol. [The UniProt Consortium]

Protein function: Converts sphingomyelin to ceramide (PubMed:1840600, PubMed:18815062, PubMed:27659707, PubMed:25920558). Also has phospholipase C activities toward 1,2-diacylglycerolphosphocholine and 1,2-diacylglycerolphosphoglycerol. [The UniProt Consortium]

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human ASM. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human ASM. Next,...

0.5mg/ml if reconstituted with 0.2ml sterile DI water. Sphingomyelin phosphodiesterase 1 (SMPD1), also known as acid sphingomyelinase (ASM or aSMase), is an enzyme that in humans is encoded by the SMPD1 gene. Enables acid sphingomyelin phosphodiesterase activity and zinc ion binding activity. Involved in ceramide...

Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 47-631aa. Protein Length: Full Length of Mature Protein. Tag Info: N-terminal 6xHis-tagged. Target Protein Sequence: LALSDSRVLW APAEAHPLSP QGHPARLHRI VPRLRDVFGW GNLTCPICKG LFTAINLGLK KEPNVARVGS VAIKLCNLLK IAPPAVCQSI VHLFEDDMVE VWRRSVLSPS EACGLLLGST...

Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 47-631aa. Protein Length: Full Length of Mature Protein. Tag Info: N-terminal 6xHis-SUMO-tagged. Target Protein Sequence: LALSDSRVLW APAEAHPLSP QGHPARLHRI VPRLRDVFGW GNLTCPICKG LFTAINLGLK KEPNVARVGS VAIKLCNLLK IAPPAVCQSI VHLFEDDMVE VWRRSVLSPS...

Organism: Homo sapiens (Human). Source: Mammalian cell. Expression Region: 47-631aa. Protein Length: Full Length of Mature Protein. Tag Info: C-terminal 10xHis-tagged. Target Protein Sequence: LALSDSRVLW APAEAHPLSP QGHPARLHRI VPRLRDVFGW GNLTCPICKG LFTAINLGLK KEPNVARVGS VAIKLCNLLK IAPPAVCQSI VHLFEDDMVE VWRRSVLSPS...