- Search results for K12320
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16 products were found matching "K12320"!
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Item number: Cay24085-1
Linaclotide is a peptide agonist of the guanylate cyclase C receptor (Ki = 16.4 nM in a radioligand binding assay using mouse intestinal mucosa). Luminal exposure to 5 µg of linaclotide stimulates fluid secretion and cGMP concentration in jejunal loops isolated from wild-type mice but not guanylate cyclase C...
Keywords: | L-cysteinyl-L-cysteinyl-L-alpha-glutamyl-L-tyrosyl-L-cysteinyl-L-cysteinyl-L-asparaginyl-L-prolyl-L-alanyl-L-cysteinyl-L-t... |
Application: | Guanylate cyclase C receptor / enterotoxin receptor agonist |
CAS | 851199-59-2 |
MW: | 1526.7 D |
From 43.00€
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Item number: ARG10785.50
Protein function: Receptor for the E.coli heat-stable enterotoxin (E.coli enterotoxin markedly stimulates the accumulation of cGMP in mammalian cells expressing GC-C). Also activated by the endogenous peptide guanylin. [The UniProt Consortium]
Keywords: | Anti-GC-C, Anti-Guc2c, Anti-Gucy2c, EC=4.6.1.2, Anti-STA receptor, Anti-Guanylyl cyclase C, Anti-Intestinal guanylate... |
Application: | IF, Dot Blot, ELISA, ICC, IF, IHC, WB |
Host: | Rabbit |
Species reactivity: | human, mouse, rat |
576.00€
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Item number: G-HUFI01379.96
Application: | ELISA |
Species reactivity: | human |
641.00€
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Item number: Cay28798-500
Linaclotide-d4 is intended for use as an internal standard for the quantification of linaclotide (Cay-24085) by GC- or LC-MS. Linaclotide is a peptide agonist of the guanylate cyclase C receptor (Ki = 16.4 nM in a radioligand binding assay using mouse intestinal mucosa). Luminal exposure to 5 µg of linaclotide...
Keywords: | ((3S,6R,15R,20R,23S,26R,29R,32R,37R,40S,45aS)-32-amino-40-(2-amino-2-oxoethyl)-26-(2-carboxyethyl)-23-(4-hydroxybenzyl)-9-... |
Application: | GC-MS, LC-MS, Internal standard, Quantification, Intestinal guanylate cyclase agonist |
MW: | 1530.8 D |
895.00€
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Item number: Cay33140-1
Guanylin is a peptide hormone activator of membrane-bound guanylate cyclase C (GC-C). It contains four cysteines that can form disulfide bridges leading to two possible isoforms, with the active form containing disulfide bridges between Cys4 and Cys12 and Cys7 and Cys15. Guanylin is found in epithelial cells of the...
Keywords: | L-prolylglycyl-L-threonyl-L-cysteinyl-L-alpha-glutamyl-L-isoleucyl-L-cysteinyl-L-alanyl-L-tyrosyl-L-alanyl-L-alanyl-L-cyst... |
Application: | GUCY2C peptide hormone activator |
MW: | 1458.7 D |
From 323.00€
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Item number: Cay33878-1
Plecanatide is a peptide agonist of the guanylate cyclase C receptor. It stimulates cGMP production in T84 colon cancer cells (EC50 = 170 nM). Plecanatide (10 ppm in the diet) reduces increases in the number of neoplastic colon epithelial cells expressing Ki-67, a marker of cell proliferation, induced by dextran...
Keywords: | SP-304,... |
Application: | GUCY2C peptide agonist |
CAS | 1075732-84-1 |
MW: | 1741.9 D |
From 84.00€
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Item number: G-CAB10562.100
Application: | WB |
Host: | Rabbit |
Species reactivity: | mouse |
From 352.00€
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Item number: ATA-HPA037655.100
Protein function: Receptor for the E.coli heat-stable enterotoxin (E.coli enterotoxin markedly stimulates the accumulation of cGMP in mammalian cells expressing GC-C). Also activated by the endogenous peptides guanylin and uroguanylin. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium...
Keywords: | Anti-GC-C, Anti-GUC2C, Anti-hSTAR, Anti-GUCY2C, EC=4.6.1.2, Anti-STA receptor, Anti-Guanylyl cyclase C, Anti-Intestinal... |
Application: | IHC |
Host: | Rabbit |
Species reactivity: | human |
From 300.00€
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Item number: E-AB-90207.120
This gene encodes a transmembrane protein that functions as a receptor for endogenous peptides guanylin and uroguanylin, and the heat-stable E. coli enterotoxin. The encoded protein activates the cystic fibrosis transmembrane conductance regulator. Mutations in this gene are associated with familial diarrhea...
Keywords: | GC-C, GUC2C, hSTAR, STA receptor, Guanylyl cyclase C, Intestinal guanylate cyclase, Heat-stable enterotoxin receptor,... |
Application: | WB |
Host: | Rabbit |
Species reactivity: | human, mouse |
From 198.00€
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Item number: ELK-ELK9881.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human GUCY2C. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human GUCY2C....
Keywords: | GC-C, GUC2C, hSTAR, STA receptor, Guanylyl cyclase C, Intestinal guanylate cyclase, Heat-stable enterotoxin receptor |
Application: | ELISA |
Species reactivity: | human |
From 365.00€
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Item number: VHPS-3931
Primers are provided as a 40 µl solution containing both primers at a final concentration of 50 µM in 10 mM Tris-HCl (pH 7.5), 0.1 mM EDTA. Dilute with water as needed prior to use. This amount is sufficient for 1000 x 20µl PCR reactions assuming a final primer concentration of 0.1 µM. Add cDNA template....
Keywords: | GC-C, hSTAR, GUC2C, GUCY2C, EC=4.6.1.2, STA receptor, Guanylyl cyclase C, Intestinal guanylate cyclase, Heat-stable... |
Application: | RNA quantification |
43.00€
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Item number: VMPS-2692
Primers are provided as a 40 µl solution containing both primers at a final concentration of 50 µM in 10 mM Tris-HCl (pH 7.5), 0.1 mM EDTA. Dilute with water as needed prior to use. This amount is sufficient for 1000 x 20µl PCR reactions assuming a final primer concentration of 0.1 µM. Add cDNA template....
Keywords: | GC-C, Guc2c, Gucy2c, EC=4.6.1.2, STA receptor, Guanylyl cyclase C, Intestinal guanylate cyclase, Heat-stable enterotoxin... |
Application: | RNA quantification |
43.00€
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