- Search results for K11838
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54 products were found matching "K11838"!
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Item number: A300-034A-T
Ubiquitin (Ub) is a highly conserved protein found ubiquitously in eukaryotic organisms. The conjugation of ubiquitin to proteins is an important means to regulate protein activity for many cellular processes by tagging them for degradation. Removal of Ub can rescue proteins from degradation. This is accomplished by...
Keywords: | Anti-HAUSP, Anti-Ubiquitin thioesterase 7, Anti-Deubiquitinating enzyme 7, Anti-Ubiquitin carboxyl-terminal hydrolase 7,... |
Application: | WB, IHC |
Host: | Rabbit |
Species reactivity: | human, mouse |
164.00€
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Item number: A300-033A
Protein function: Hydrolase that deubiquitinates target proteins such as FOXO4, p53/TP53, MDM2, ERCC6, DNMT1, UHRF1, PTEN and DAXX (PubMed:11923872, PubMed:15053880, PubMed:16964248, PubMed:18716620, PubMed:25283148). Together with DAXX, prevents MDM2 self-ubiquitination and enhances the E3 ligase activity of MDM2...
Keywords: | Anti-USP7, Anti-HAUSP, Anti-Ubiquitin thioesterase 7, Anti-Deubiquitinating enzyme 7, Anti-Ubiquitin carboxyl-terminal... |
Application: | WB, IP, IHC |
Host: | Rabbit |
Species reactivity: | human, mouse |
From 164.00€
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Item number: IHC-00018
Protein function: Hydrolase that deubiquitinates target proteins such as FOXO4, p53/TP53, MDM2, ERCC6, DNMT1, UHRF1, PTEN and DAXX (PubMed:11923872, PubMed:15053880, PubMed:16964248, PubMed:18716620, PubMed:25283148). Together with DAXX, prevents MDM2 self-ubiquitination and enhances the E3 ligase activity of MDM2...
Keywords: | Anti-USP7, Anti-HAUSP, Anti-Ubiquitin thioesterase 7, Anti-Deubiquitinating enzyme 7, Anti-Ubiquitin carboxyl-terminal... |
Application: | IHC, IHC-IF |
Host: | Rabbit |
Species reactivity: | human, mouse |
From 164.00€
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Item number: A300-034A
Protein function: Hydrolase that deubiquitinates target proteins such as FOXO4, p53/TP53, MDM2, ERCC6, DNMT1, UHRF1, PTEN and DAXX (PubMed:11923872, PubMed:15053880, PubMed:16964248, PubMed:18716620, PubMed:25283148). Together with DAXX, prevents MDM2 self-ubiquitination and enhances the E3 ligase activity of MDM2...
Keywords: | Anti-USP7, Anti-HAUSP, Anti-Ubiquitin thioesterase 7, Anti-Deubiquitinating enzyme 7, Anti-Ubiquitin carboxyl-terminal... |
Application: | WB, IP, IHC |
Host: | Rabbit |
Species reactivity: | human, mouse, rat |
588.00€
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Item number: A303-943A
Protein function: Hydrolase that deubiquitinates target proteins such as FOXO4, p53/TP53, MDM2, ERCC6, DNMT1, UHRF1, PTEN and DAXX (PubMed:11923872, PubMed:15053880, PubMed:16964248, PubMed:18716620, PubMed:25283148). Together with DAXX, prevents MDM2 self-ubiquitination and enhances the E3 ligase activity of MDM2...
Keywords: | Anti-USP7, Anti-HAUSP, Anti-Ubiquitin thioesterase 7, Anti-Deubiquitinating enzyme 7, Anti-Ubiquitin carboxyl-terminal... |
Application: | WB, IP, IHC |
Host: | Goat |
Species reactivity: | human, mouse |
From 164.00€
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Item number: Cay23759-1
HBX 41108 is an uncompetitive, reversible inhibitor of ubiquitin-specific protease 7 (USP7) activity (IC50 = 424 nM). It dose-dependently inhibits USP7-mediated p53 deubiquitination in a cell-free assay, with an IC50 value of approximately 0.8 µM, as well as in HEK293 cells. It is selective for USP7 over a panel of...
Keywords: | 7-chloro-9-oxo-9H-indeno[1,2-b]pyrazine-2,3-dicarbonitrile |
Application: | USP7 inhibitor |
CAS | 924296-39-9 |
MW: | 266.6 D |
From 50.00€
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Item number: Cay15224-5
Ubiquitin-specific proteases (USP/UBP) remove ubiquitin from proteins, sparing them from degradation by the proteasome. USP7 is a cysteine protease associated with prostate cancer that selectively deubiquitylates HDM2, the ubiquitin E3 ligase for the tumor suppressor p53. P005091 is a trisubstituted thiophene that...
Keywords: | P5091, 1-[5-[(2,3-dichlorophenyl)thio]-4-nitro-2-thienyl]-ethanone |
Application: | USP7 / USP47 inhibitor |
CAS | 882257-11-6 |
MW: | 348.2 D |
From 89.00€
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Item number: BPS-79256
The USP7 Inhibitor Screening Assay Kit is designed to measure USP7 activity for screening and profiling applications. The USP7 Inhibitor Screening Assay Kit comes in a convenient format, with a 96-well plate, fluorogenic, ubiquitinated substrate, assay buffer, and purified USP7 enzyme for 96 enzyme reactions. USP7...
Keywords: | Ubiquitin thioesterase 7, Deubiquitinating enzyme 7, Ubiquitin carboxyl-terminal hydrolase 7,... |
Application: | Enzyme kinetics, HTS |
Species reactivity: | human |
1,202.00€
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Item number: BPS-80395
Human ubiquitin specific peptidase 7 (USP7) or HAUSP, GenBank Accession No. NM_003470, a.a. 2 ? 1102 (end) with N-terminal His-Flag tag, MW = 130 kDa, expressed in an E. coli cell expression system.
Keywords: | Ubiquitin thioesterase 7, Deubiquitinating enzyme 7, Ubiquitin carboxyl-terminal hydrolase 7,... |
Application: | Enzyme kinetics, inhibitor screening, selectivity profiling |
Expressed in: | E.coli |
Origin: | human |
MW: | 130 kD |
628.00€
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Item number: 600-401-482
Protein function: Hydrolase that deubiquitinates target proteins such as FOXO4, p53/TP53, MDM2, ERCC6, DNMT1, UHRF1, PTEN and DAXX. Together with DAXX, prevents MDM2 self-ubiquitination and enhances the E3 ligase activity of MDM2 towards p53/TP53, thereby promoting p53/TP53 ubiquitination and proteasomal...
Keywords: | Anti-USP7, Anti-HAUSP, EC=3.4.19.12, Anti-Ubiquitin thioesterase 7, Anti-Deubiquitinating enzyme 7, Anti-Ubiquitin... |
Application: | ELISA, WB |
Host: | Rabbit |
Species reactivity: | human |
684.00€
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Item number: BPS-27767-1
P005091 is a selective, potent inhibitor of USP7 deubiquitylating activity.
Keywords: | P005091, P5091, |
Application: | USP7 inhibitor |
MW: | 348.2 D |
From 307.00€
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Item number: Cay16893-5
Protein ubiquitination is a dynamic process that can be reversed by deubiquitinating enzymes (DUBs) that remove ubiquitin from proteins, sparing them from degradation by the proteasome. The DUBs have been divided into various groups, the largest being the ubiquitin-specific proteases (USPs). NSC 632839 inhibits USP2...
Keywords: | F6, Ubiquitin Isopeptidase Inhibitor II, 3,5-bis[(4-methylphenyl)methylene]-4-piperidinone, monohydrochloride |
Application: | USP2 / USP7 / SENP2 inhibitor |
CAS | 157654-67-6 |
MW: | 339.9 D |
From 43.00€
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