18 products were found matching "K11787"!
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Pemetrexed (sodium salt hydrate)
Item number: Cay14269-5
Pemetrexed is an antifolate with anticancer activity. It is an inhibitor of folate-dependent enzymes involved in purine synthesis, including thymidylate synthase and dihydrofolate reductase (Kis = 109 and 7 nM, respectively, for the human recombinant enzymes), and the potency for thymidylate kinase is increased...
| Keywords: | N-[4-[2-(2-amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic acid, disodium salt,... |
| Application: | Antifolate |
| CAS | 357166-29-1 |
| MW: | 597.5 D |
From 82.00€
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Azaserine
Item number: Cay14834-10
Azaserine is a tumor-inhibiting antibiotic isolated from a species of Streptomyces that functions as a glutamine analog. At 25 µM, it inhibits the glutamine-dependent amidotransferases involved in nucleotide biosynthesis, phosphoribosylformylglycinamidine synthetase and glucosamine-6-phosphate isomerase. Azaserine...
| Keywords: | CI-337, CN 15757, NSC 742, O-Diazoacetyl-L-serine, O-(2-diazoacetyl)-L-serine |
| Application: | Tumor-inhibiting antibiotic, glutamine analog |
| CAS | 115-02-6 |
| MW: | 173.1 D |
From 50.00€
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Lometrexol (hydrate)
Item number: Cay18049-1
Glycinamide ribonucleotide formyltransferase (GART) is a folate-dependent enzyme required for de novo purine synthesis. Lometrexol is a folate analog antimetabolite with antineoplastic activity. At nanomolar conentrations, it inhibits GART preventing de novo purine synthesis, inhibiting DNA synthesis, arresting...
| Keywords: | (6R)-Dideazatetrahydrofolate, DDATHF,... |
| Application: | GART inhibitor |
| MW: | 443.5 D |
From 130.00€
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Anti-GART
Item number: A304-311A
GART is a trifunctional polypeptide. It has phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase activity which is required for de novo purine biosynthesis. This enzyme is highly conserved in vertebrates [taken from NCBI Entrez Gene (Gene ID: 2618)].
| Keywords: | Anti-AIRS, Anti-GARS, Anti-GART, Anti-PGFT, EC=2.1.2.2, EC=6.3.3.1, EC=6.3.4.13, Anti-AIR synthase, Anti-GAR... |
| Application: | WB, IP, IHC |
| Host: | Rabbit |
| Species reactivity: | human, mouse |
From 164.00€
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Anti-GART
Item number: A304-312A
GART is a trifunctional polypeptide. It has phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase activity which is required for de novo purine biosynthesis. This enzyme is highly conserved in vertebrates [taken from NCBI Entrez Gene (Gene ID: 2618)].
| Keywords: | Anti-AIRS, Anti-GARS, Anti-GART, Anti-PGFT, EC=2.1.2.2, EC=6.3.3.1, EC=6.3.4.13, Anti-AIR synthase, Anti-GAR... |
| Application: | WB, IP, IHC |
| Host: | Rabbit |
| Species reactivity: | human, mouse |
From 164.00€
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Pemetrexed Disodium
Item number: LKT-P1849.10
Thymidylate synthase inhibitor, potential SHMT, DNFR, GARFT inhibitor.
| Application: | Glycinamide ribonucleotide formyltransferase (GARFT) inhibitor, thymidylate synthase inhibitor |
| CAS | 150399-23-8 |
| MW: | 471.37 D |
From 90.00€
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Anti-GART
Item number: E-AB-62752.120
The protein encoded by this gene is a trifunctional polypeptide. It has phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase activity which is required for de novo purine biosynthesis. This enzyme is highly conserved in vertebrates. Alternative...
| Keywords: | Anti-GART, Anti-AIRS, Anti-PGFT, Anti-GARS, EC=2.1.2.2, EC=6.3.3.1, EC=6.3.4.13, Anti-AIR synthase, Anti-GAR... |
| Application: | WB |
| Host: | Rabbit |
| Species reactivity: | human, mouse |
From 198.00€
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Anti-GART
Item number: ARG58720.100
| Keywords: | Anti-GARS, Anti-AIRS, Anti-GART, Anti-PGFT, EC=6.3.3.1, EC=2.1.2.2, EC=6.3.4.13, Anti-AIR synthase, Anti-GAR... |
| Application: | WB |
| Host: | Rabbit |
| Species reactivity: | human, mouse |
624.00€
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Anti-GART
Item number: E-AB-17989.120
The protein encoded by this gene is a trifunctional polypeptide. It has phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase activity which is required for de novo purine biosynthesis. This enzyme is highly conserved in vertebrates. Alternative...
| Keywords: | Anti-GART, Anti-PGFT, Anti-GARS, Anti-AIRS, EC=2.1.2.2, EC=6.3.3.1, EC=6.3.4.13, Anti-AIR synthase, Anti-GAR... |
| Application: | IHC, ELISA |
| Host: | Rabbit |
| Species reactivity: | human, mouse |
From 71.00€
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Anti-GART
Item number: G-CAB3876.100
| Application: | WB |
| Host: | Rabbit |
| Species reactivity: | human, mouse |
From 352.00€
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Anti-GART
Item number: ATA-HPA002119.100
Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 86% and to rat: 87%
| Keywords: | Anti-GARS, Anti-AIRS, Anti-PGFT, Anti-GART, EC=2.1.2.2, EC=6.3.3.1, EC=6.3.4.13, Anti-AIR synthase, Anti-GAR... |
| Application: | IHC, WB |
| Host: | Rabbit |
| Species reactivity: | human, mouse, rat |
From 335.00€
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Anti-GART
Item number: ATA-HPA005779.100
Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 78% and to rat: 82%
| Keywords: | Anti-GARS, Anti-AIRS, Anti-PGFT, Anti-GART, EC=2.1.2.2, EC=6.3.3.1, EC=6.3.4.13, Anti-AIR synthase, Anti-GAR... |
| Application: | IHC |
| Host: | Rabbit |
| Species reactivity: | human |
From 335.00€
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