22 products were found matching "K11724"!

0.5mg/ml if reconstituted with 0.2ml sterile DI water. Bromodomain testis-specific protein is a protein that in humans is encoded by the BRDT gene. BRDT is similar to the RING3 protein family. It possesses 2 bromodomain motifs and a PEST sequence (a cluster of proline, glutamic acid, serine, and threonine residues),...

MZ1 is a hybrid compound that drives the selective proteasomal degradation of bromodomain-containing protein 4 (BRD4). It is characterized as a proteolysis-targeting chimera (PROTAC) and contains JQ-1, which binds bromo- and extra-terminal (BET) proteins, linked to a ligand for the E3 ubiquitin ligase VHL. MZ1...

ABBV-744 is an inhibitor of the bromodomain and extra-terminal domain (BET) family protein bromodomain 2 (BD2, Kis = 4.6, 4.9, 1.6, and 1 nM for BRD2, -3, -4, and -T, respectively). It is selective for BD2 over BD1 bromodomains in a time-resolved FRET (TR-FRET) assay (Kis = 1,162, 3,140, 521, and 917 nM for BRD2,...

Human Bromodomain testis-specific protein, also known as BRDT, BRD6, and CT9, amino-acids 257 ? 382 (GenBank Accession No. NM_207189) with N-terminal GST tag, MW = 41.7 kDa, expressed in an E. coli expression system.

Human Bromodomain testis-specific protein, also known as BRDT, BRD6, and CT9, amino-acids 22 ? 382 (GenBank Accession No. NM_207189) with N-terminal GST tag, MW = 68.1 kDa, expressed in an E. coli expression system.

Human Bromodomain testis-specific protein, also known as BRDT, BRD6, and CT9, amino-acids 257-382 (GenBank Accession No. NM_207189) with N-terminal HIS tag, MW = 15.8 kDa, expressed in an E. coli expression system.

Human Bromodomain testis-specific protein, also known as BRDT, BRD6, and CT9, amino-acids 22-138 (GenBank Accession No. NM_207189) with N-terminal HIS tag, MW = 14.9 kDa, expressed in an E. coli expression system.

Human Bromodomain testis-specific protein, also known as BRDT, BRD6, and CT9, amino-acids 22 ? 138 (GenBank Accession No. NM_207189) with N-terminal GST tag, MW = 40.7 kDa, expressed in an E.coli expression system.

Protein function: Testis-specific chromatin protein that specifically binds histone H4 acetylated at 'Lys-5' and 'Lys-8' (H4K5ac and H4K8ac, respectively) and plays a key role in spermatogenesis. Required in late pachytene spermatocytes: plays a role in meiotic and post-meiotic cells by binding to acetylated...

In 1X PBS, pH 7.4, with 0.09% sodium azide. BRDT is similar to the RING3 protein family. It possesses 2 bromodomain motifs and a PEST sequence (a cluster of proline, glutamic acid, serine, and threonine residues), characteristic of proteins that undergo rapid intracellular degradation. The bromodomain is found in...

Key Features Cayman's BRDT bromodomain 1 TR-FRET Assay Kit (Cay-600650) was developed using BRDT bromodomain 1 (human, recombinant) protein.Bulk sizes available upon request The acetylation of histone lysine residues plays a crucial role in the epigenetic regulation of gene transcription. Acetylated lysine residues...

The acetylation of histone lysine residues plays a crucial role in the epigenetic regulation of gene transcription. Acetylated lysine residues are recognized by a small protein domain known as a bromodomain. These domains function in the linking of protein complexes to acetylated nucleosomes, thereby controlling...