128 products were found matching "K11647"!
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Probable global transcription activator SNF2L2 (SMARCA2),...
Item number: CSB-MP021799HU4.1
Organism: Homo sapiens (Human). Source: Mammalian cell. Expression Region: 1350-1520aa. Protein Length: Partial. Tag Info: C-terminal hFc-tagged. Target Protein Sequence: RNVDKDPAKE DVEKAKKRRG RPPAEKLSPN PPKLTKQMNA IIDTVINYKD RCNVEKVPSN SQLEIEGNSS GRQLSEVFIQ LPSRKELPEY YELIRKPVDF KKIKERIRNH KYRSLGDLEK DVMLLCHNAQ...
| Keywords: | hBRM, BAF190B, EC=3.6.4.-, SNF2-alpha, Protein brahma homolog, BRG1-associated factor 190B, ATP-dependent helicase... |
| Application: | Activity not tested |
| Expressed in: | Mammalian cells |
| Origin: | human |
| MW: | 47.4 kD |
From 371.00€
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ACBI1
Item number: Cay36612-1
ACBI1 is a proteolysis-targeting chimera (PROTAC) composed of a ligand for BRM, also known as SMARCA2, BRG1, also known as SMARCA4, and polybromo-1D (PBRM1), which are components of switch/sucrose nonfermentable (SWI/SNF) chromatin remodeling complexes, conjugated to a von Hippel-Lindau (VHL) E3 ligase ligand. It...
| Keywords: | (2S,4R)-N-(2-(2-(4-((4-(3-amino-6-(2-hydroxyphenyl)pyridazin-4-yl)piperazin-1-yl)methyl)phenoxy)ethoxy)-4-(4-methylthiazol... |
| Application: | BRM / BRG1 / PBRM1 degradation driving PROTAC |
| CAS | 2375564-55-7 |
| MW: | 936.1 D |
From 98.00€
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FHD-286
Item number: LKT-F130280.1
FHD-286 is a BRG1/BRM ATPase inhibitor, which is associated with tumor development and progression. SMILES: CC1CN(CC(O1)C)C2=CC=CC(=N2)C3=CSC(=N3)NC(=O)C(COC)NC(=O)C4=CN(C=C4)S(=O)(=O)C
| Keywords: | FHD286,... |
| Application: | BRG1/BRM ATPase inhibitor |
| CAS | 2671128-05-3 |
| MW: | 562.66 D |
From 275.00€
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Anti-SMARCA4
Item number: ABS-KC-6076.100
Protein function: Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Component of SWI/SNF chromatin remodeling complexes that carry out key enzymatic activities, changing chromatin structure by altering DNA-histone contacts within a...
| Keywords: | Anti-Transcription activator BRG1, Anti-ATP-dependent helicase SMARCA4, Anti-BRG1-associated factor 190A, Anti-BAF190A,... |
| Host: | Mouse |
| Species reactivity: | human |
From 232.00€
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Anti-SMARCA4
Item number: ABS-KC-6170.100
Protein function: Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Component of SWI/SNF chromatin remodeling complexes that carry out key enzymatic activities, changing chromatin structure by altering DNA-histone contacts within a...
| Keywords: | Anti-Transcription activator BRG1, Anti-ATP-dependent helicase SMARCA4, Anti-BRG1-associated factor 190A, Anti-BAF190A,... |
| Host: | Mouse |
| Species reactivity: | human, mouse |
From 232.00€
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Anti-ABCB5, clone CL13779
Item number: ATA-AMAb91895.25
Monoclonal Antibody against Human SMARCA4, Clone ID: CL13779, Gene description: Swi/snf related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4, Alternative Gene Names: BAF190, BRG1, FLJ39786, hSNF2b, SNF2, SNF2-BETA, SNF2L4, SNF2LB, SWI2, Validated applications: ICC, WB, Uniprot...
| Keywords: | Anti-SMARCA4, Anti-BAF190A, Anti-SNF2-beta, EC=3.6.4.-, Anti-Protein BRG-1, Anti-Protein brahma homolog 1,... |
| Application: | WB, ICC |
| Host: | Mouse |
| Species reactivity: | human |
320.00€
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Anti-ABCB5, clone CL13783
Item number: ATA-AMAb91897.25
Monoclonal Antibody against Human SMARCA4, Clone ID: CL13783, Gene description: Swi/snf related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4, Alternative Gene Names: BAF190, BRG1, FLJ39786, hSNF2b, SNF2, SNF2-BETA, SNF2L4, SNF2LB, SWI2, Validated applications: IHC, Uniprot ID:...
| Keywords: | Anti-SMARCA4, Anti-BAF190A, Anti-SNF2-beta, EC=3.6.4.-, Anti-Protein BRG-1, Anti-Protein brahma homolog 1,... |
| Application: | IHC |
| Host: | Mouse |
| Species reactivity: | human |
320.00€
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FHD-286
Item number: Cay41864-1
FHD-286 is an inhibitor of Brahma homolog (BRM), also known as SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2 (SMARCA2), and Brahma-related gene 1 (BRG1), also known as SMARCA4. It induces differentiation of, and reduces viability in, MV4-11 and MOLM-13 acute myeloid...
| Keywords: | N-[(1S)-2-[[4-[6-[(2R,6S)-2,6-dimethyl-4-morpholinyl]-2-pyridinyl]-2-thiazolyl]amino]-1-(methoxymethyl)-2-oxoethyl]-1-(met... |
| Application: | BRM (SMARCA2) / BRG1 (SMARCA4) inhibitor |
| CAS | 2671128-05-3 |
| MW: | 562.7 D |
From 85.00€
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Anti-BRG1/SMARCA4 (IHC)
Item number: IHC-00466
Protein function: Transcriptional coactivator cooperating with nuclear hormone receptors to potentiate transcriptional activation. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an...
| Keywords: | Anti-SMARCA4, Anti-BAF190A, Anti-SNF2-beta, EC=3.6.4.-, Anti-Protein BRG-1, Anti-Protein brahma homolog 1,... |
| Application: | IHC |
| Host: | Rabbit |
| Species reactivity: | human, mouse |
From 178.00€
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Anti-BRG1/SMARCA4
Item number: A300-813A
Protein function: Transcriptional coactivator cooperating with nuclear hormone receptors to potentiate transcriptional activation. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an...
| Keywords: | Anti-SMARCA4, Anti-BAF190A, Anti-SNF2-beta, EC=3.6.4.-, Anti-Protein BRG-1, Anti-Protein brahma homolog 1,... |
| Application: | WB, IP, IHC |
| Host: | Rabbit |
| Species reactivity: | human, mouse |
From 178.00€
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Anti-BRG1/SMARCA4
Item number: A303-877A
Protein function: Transcriptional coactivator cooperating with nuclear hormone receptors to potentiate transcriptional activation. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an...
| Keywords: | Anti-SMARCA4, Anti-BAF190A, Anti-SNF2-beta, EC=3.6.4.-, Anti-Protein BRG-1, Anti-Protein brahma homolog 1,... |
| Application: | WB, IP, IHC |
| Host: | Goat |
| Species reactivity: | human, mouse |
From 178.00€
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BRM/BRG1 ATP Inhibitor-2
Item number: TGM-T60032-100mg
Description: BRM/BRG1 ATP Inhibitor-2 is a BRG1/BRM ATPase inhibitor, suitable for studies on the treatment of BAF-related disorders. Target: Epigenetic Reader Domain. Smiles: CSCC[C@H](NC(=O)c1cccnc1)C(=O)Nc1nc(cs1)-c1ccccc1. References: Neville John ANTHONY, et al. Compounds and uses thereof. WO2019152437A1.
| Application: | SMARCA2A/SMARCA4 ATPase inhibitor |
| CAS | 2368900-77-8 |
| MW: | 412.53 D |
From 57.00€
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