59 products were found matching "K11588"!

Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml. MECP2 antibody detects Methyl-CpG-binding protein 2, a nuclear chromatin-associated protein that binds methylated DNA and regulates gene expression. The UniProt recommended name is Methyl-CpG-binding protein 2 (MECP2). This transcriptional...

Protein function: Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Mediates transcriptional repression through interaction with histone deacetylase and the corepressor SIN3A. Binds both 5-methylcytosine...

Human recombinant Methyl CpG binding Protein 2 (Rett syndrome) (MECP2), GenBank Accession #NM_004992), a.a.78-162 with N-terminal GST-tag, MW= 36kDa, expressed in an E. coli expression system.

DNA methylation, or the addition of methyl groups to cytosine bases in the dinucleotide CpG, is imperative to proper development and regulates gene expression. The methylation pattern involves the enzymatic processes of methylation and demethylation. A demethylase enzyme has been identified which exhibits...

Protein function: Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Mediates transcriptional repression through interaction with histone deacetylase and the corepressor SIN3A. Binds both 5-methylcytosine...

Protein function: Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Mediates transcriptional repression through interaction with histone deacetylase and the corepressor SIN3A. Binds both 5-methylcytosine...

MeCP2 (UniProt/Swiss Prot entry P51608) is a chromosomal protein with abundant binding sites in the chromatin. It belongs to the family of methyl CpG binding proteins which also comprises MBD1, MBD2, MBD3 and MBD4. MeCP2 can bind specifically to methylated promoters, thereby repressing transcription. This...

DNA methylation occurs mainly at the 5'-position of cytosine rings (5-methylcytosine (5mC)). The 5mC bases are found largely in genomic regions with a high frequency of cytosines and guanines, called CpG islands. Methyl-CpG binding protein 2 (MeCP2) specifically binds to methylated promoters on CpG islands and...

Anti-MeCP2 pS80 antibody was prepared from monospecific neat serum. This antibody is specific for the ~75 kDa MECP2 protein phosphorylated at Ser 80 in Western blots of human, rat and mouse brain extracts. Reactivity is expected against mouse and rat. Protein function: Chromosomal protein that binds to methylated...

Anti-MeCP2 Antibody was purified by affinity purification. This product reacts with human MeCP2.  Cross reactivity with MeCP2 from species other than human is not known. Protein function: Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by...

In 1X PBS, pH 7.4, with 0.09% sodium azide. MeCP2 is a chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Mediates transcriptional repression through interaction with histone deacetylase and the...

In 1X PBS, pH 7.4, with 0.09% sodium azide. DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain...