90 products were found matching "K11459"!

Formulation: Purified Ab WITHOUT BSA and Azide at 1.0mg/ml. Cellular Localization: Cytoplasm, Nucleus. Positive Control: HeLa or Jurkat cells. Colon Carcinoma. Chromosome Location: 10p12.2.3. Protein Function: Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain...

Formulation: Purified Ab WITHOUT BSA and Azide at 1.0mg/ml. Cellular Localization: Cytoplasm, Nucleus. Positive Control: 293T, HeLa or Jurkat cells. Colon Carcinoma., NIH3T3. Chromosome Location: 10p12.2.3. Protein Function: Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required...

Formulation: Purified Ab with BSA and Azide at 200ug/ml. Cellular Localization: Cytoplasm, Nucleus. Positive Control: HeLa or Jurkat cells. Colon Carcinoma. Chromosome Location: 10p12.2.3. Protein Function: Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the...

Formulation: Purified Ab with BSA and Azide at 200ug/ml. Cellular Localization: Cytoplasm, Nucleus. Positive Control: 293T, HeLa or Jurkat cells. Colon Carcinoma., NIH3T3. Chromosome Location: 10p12.2.3. Protein Function: Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to...

Formulation: Purified Ab with BSA and Azide at 200ug/ml. Cellular Localization: Cytoplasm, Nucleus. Positive Control: HeLa or Jurkat cells. Colon Carcinoma. Chromosome Location: 10p12.2.3. Protein Function: Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the...

Formulation: Purified Ab WITHOUT BSA and Azide at 1.0mg/ml. Cellular Localization: Cytoplasm, Nucleus. Positive Control: HeLa or Jurkat cells. Colon Carcinoma. Chromosome Location: 10p12.2.3. Protein Function: Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain...

This gene encodes a ring finger protein that is major component of the polycomb group complex 1 (PRC1). This complex functions through chromatin remodeling as an essential epigenetic repressor of multiple regulatory genes involved in embryonic development and self-renewal in somatic stem cells. This protein also...

Protein function: Component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, it mediates...

Polycomb complex protein BMI-1 is a polycomb ring finger oncogene that regulates the p16 and p19 cell cycle inhibitor genes. It is necessary for efficient self-renewing cell divisions of stem cells in several tissues and can be over-expressed in tumors. PTC-209 is a BMI-1 inhibitor (IC50 = ~ 0.5 µM) that...

Protein function: Component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, it mediates...

PTC-596 is an inhibitor of B cell-specific Moloney murine leukemia virus integration site 1 (BMI1), which is a member of the polycomb repressive complex 1 (PRC1) that has a role in gene silencing. It inhibits proliferation of MOLM-13 acute myeloid leukemia (AML) and Rec-1 mantle cell lymphoma (MCL) cancer cells...

BMI1 (UniProtKB/Swiss Prot entry P35226) is a component of a Polycomb group (PcG) multiprotein PRC1 like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. The PcG PRC1 complex acts via chromatin remodeling and modification...