34 products were found matching "K11409"!

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human HDAC9. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human HDAC9. Next,...

Active human HDAC9 , GenBank Accession No. NM_178423, amino acids 604- 1066 with C-terminal His tag, MW= 50.7 kDa, expressed in baculovirus expression system.

TMP-195 is an inhibitor of class IIa histone deacetylases (HDACs, Kis = 59, 60, 26, and 15 nM for HDAC4, 5, 7, and 9, respectively). It is selective for class IIa HDACs over class I and class IIb HDACs (Kis = 10-43 µM for HDAC1-3, 6, 9, and 10-11). TMP-195 blocks accumulation of chemoattractant chemokine ligand 2...

The Fluorogenic HDAC9 Assay Kit is a complete assay system designed to measure histone deacetylases 9 (HDAC9) activity for screening and profiling applications. It comes in a convenient 96-well format, with all the reagents necessary for fluorescent HDAC activity measurements. In addition, the kit includes purified...

While class I HDACs are localized predominantly within the nucleus, class II HDACs shuttle into and out of the nucleus in response to intracellular signaling. Class IIa HDACs, which includes HDAC4, 5, 7, and 9, commonly act as corepressors and play diverse roles in cell biology. MC 1568 is a selective inhibitor of...

Protein function: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Represses...

HDAC9 is a Class IIa HDAC which is homologous to the yeast HDAC1 and is larger in size than the other classes of HDACs. Class IIa HDACs contain a highly conserved C-terminal deacetylase catalytic domain (~420 amino acids) and N-terminal domain with no similarity to HDACs in other classes. Class II HDACs can shuttle...

Anti-HDAC9 was affinity purified from monospecific antiserum by immunoaffinity chromatography. A BLAST analysis was used to suggest cross-reactivity with human based on 100% sequence homology. Cross-reactivity with HDAC9 from other sources has not been determined. HDAC9 is located in the nucleus, expressed most...

Anti-HDAC9 was affinity purified from monospecific antiserum by immunoaffinity chromatography. A BLAST analysis was used to suggest cross-reactivity with human based on 100% sequence homology. Cross-reactivity with HDAC9 from other sources has not been determined. HDAC9 is located in the nucleus, expressed most...

In 1X PBS, pH 7.4, with 0.09% sodium azide. Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene has sequence...

In 1X PBS, pH 7.4, with 0.09% sodium azide. Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene has sequence...

HDAC1/2/3/11 inhibitor.