61 products were found matching "K11304"!

NU 9056 was originally identified as an inhibitor of TIP60, also known as lysine acetyltransferase 5 (KAT5, IC50 = 2 µM). However, it has been shown that NU 9056 is thiol-reactive in a cell-free assay and inhibits multiple targets in biochemical and cell-based assays, indicating it is a non-selective interference...

TIP60 is a member of the MYST family of lysine acetyl transferases. It has been shown to acetylate histones, p53, and the Ataxia Telangiectasia Mutant (ATM) protein kinase. As a component of the TIP60-p400 complex, TIP60 acetylates transcription repressors in order to inhibit gene transcription. In complexes without...

MG149 is a histone acetyltransferase (HAT) inhibitor with IC50 values of 74 and 47 µM, for human recombinant Tip60 and males absent on the first (MOF) HATs, respectively. MG149 targets the acetyl-CoA binding site and inhibits acetyltransferase activity in the nuclear extract from murine hippocampus, amygdala, and...

TIP60, originally isolated as an HIV-1 TAT-interactive protein, is known to interact with the viral TAT protein that leads to HTATIP polyubiquitination and targets it for degradation. It belongs to the MYST family of histone acetyltransferases (HATs). TIP60 is a catalytic subunit of the NuA4 HAT complex which is...

Protein function: Catalytic subunit of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome-DNA interactions and promote interaction of the modified...

In 1X PBS, pH 7.4, with 0.09% sodium azide. HTATIP/Tip60 belongs to the MYST family of histone acetyl transferases (HATs) and was originally isolated as an HIV-1 TAT-interactive protein. HATs play important roles in regulating chromatin remodeling, transcription and other nuclear processes by acetylating histone and...

Full-length recombinant Human KAT5 (TIP60) protein also known as cPLA2 ESA1 HTATIP, HTATIP1, PLIP, and TIP. Genbank Accession NM_006388, with an N-terminal GST tag expressed by baculovirus in Sf9 insect cells. MW = 88kDa.

In 1X PBS, pH 7.4, with 0.09% sodium azide. HTATIP/Tip60 belongs to the MYST family of histone acetyl transferases (HATs) and was originally isolated as an HIV-1 TAT-interactive protein. HATs play important roles in regulating chromatin remodeling, transcription and other nuclear processes by acetylating histone and...

TIP60 (Phospho-Ser86) Colorimetric Cell-Based ELISA Kit Protein function: Catalytic subunit of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A (PubMed:12776177, PubMed:15042092, PubMed:15121871,...

Protein function: Catalytic subunit of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A (PubMed:12776177, PubMed:15042092, PubMed:15121871, PubMed:15310756, PubMed:14966270, PubMed:16387653,...

0.5mg/ml if reconstituted with 0.2ml sterile DI water. Histone acetyltransferase KAT5 is an enzyme that in humans is encoded by the KAT5 gene. The protein encoded by this gene belongs to the MYST family of histone acetyl transferases (HATs) and was originally isolated as an HIV-1 TAT-interactive protein. HATs play...

Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...