29 products were found matching "K10951"!

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human NKCC1. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human NKCC1. Next,...

Furosemide (Cay-26298) is an analytical reference standard categorized as a diuretic. Formulations containing diuretics, including furosemide, have been misused in sports for weight reduction and as masking agents in humans and to prevent exercise-induced pulmonary hemorrhage in racehorses. This product is intended...

Ethacrynic acid (Cay-26299) is an analytical reference standard categorized as a loop diuretic. Diuretics, including ethacrynic acid, have been used as masking agents in sports doping, including racehorse doping. This product is intended for use in analytical forensic applications. This product is also available as...

0.5mg/ml if reconstituted with 0.2ml sterile DI water. Solute carrier family 12 (sodium/potassium/chloride transporters), member 2, also known as NKCC1, is widely distributed throughout the body, especially in organs that secrete fluids, called exocrine glands. By fluorescence in situ hybridization, this gene is...

Bumetanide is an inhibitor of Na-K-2Cl cotransporter 1 (NKCC1, IC50 = 0.68 µM). It is selective for NKCC1 over NKCC2 (IC50 = 4 µM). Bumetanide is an agonist of G protein-coupled receptor 35 (GPR35, EC50 = 10 µM). It also inhibits various carbonic anhydrases. Bumetanide (0.1 mg/kg) increases urine flow and sodium and...

Furosemide-d5 is intended for use as an internal standard for the quantification of furosemide (Cay-17273) by GC- or LC-MS. Furosemide is a loop diuretic and an inhibitor of the Na+/K+/2Cl- (NKCC) cotransporters, NKCC1 and NKCC2 (Kis = ~10 µM for both). In vivo, furosemide (0.1 mg/kg, p.o.) increases diuresis in...

Bumetanide binds to Na-K-Cl co-transporter and inhibits its action.

Furosemide is a loop diuretic and an inhibitor of the Na+/K+/2Cl- (NKCC) cotransporters, NKCC1 and NKCC2 (Kis = ~10 µM for both). In vivo, furosemide (0.1 mg/kg, p.o.) increases diuresis in beagle dogs. Furosemide (30 mg/kg) reduces ventricular collagen deposition and fibrosis in a rat model of dilated...

Bumetanide-d5 is intended for use as an internal standard for the quantification of bumetanide (Cay-14630) by GC- or LC-MS. Bumetanide is an inhibitor of Na-K-2Cl cotransporter 1 (NKCC1, IC50 = 0.68 µM). It is selective for NKCC1 over NKCC2 (IC50 = 4 µM). Bumetanide is an agonist of G protein-coupled receptor 35...

Torasemide-d7 is intended for use as an internal standard for the quantification of torasemide by GC- or LC-MS. Torasemide is a loop diuretic. In vivo, torasemide (6 mg/kg) increases fractional potassium, sodium, and chloride excretion and increases urine flow in rats. Formulations containing torsemide have been...

Bumetanide is a loop diuretic that is clinically used to treat congestive heart failure. Bumetanide also exhibits anxiolytic, neuroprotective and anti-epileptic/anticonvulsant activities. Bumetanide induces hyperpolarization in kidney cells, increasing whole-cell conductance and intracellular Ca2+ levels. Bumetanide...

Protein function: Electrically silent transporter system. Mediates sodium and chloride reabsorption. Plays a vital role in the regulation of ionic balance and cell volume. [The UniProt Consortium]