- Search results for K10405
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32 products were found matching "K10405"!
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Item number: A300-951A
Protein function: Minus end-directed microtubule-dependent motor required for bipolar spindle formation (PubMed:15843429). May contribute to movement of early endocytic vesicles. Regulates cilium formation and structure. [The UniProt Consortium]
| Keywords: | Anti-HSET, Anti-KIFC1, Anti-Kinesin-like protein 2, Anti-Kinesin-like protein KIFC1, Anti-Kinesin-related protein HSET |
| Application: | WB, IP, IHC |
| Host: | Rabbit |
| Species reactivity: | human |
From 165.00€
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Item number: A300-952A-T
Protein function: Minus end-directed microtubule-dependent motor required for bipolar spindle formation (PubMed:15843429). May contribute to movement of early endocytic vesicles. Regulates cilium formation and structure. [The UniProt Consortium]
| Keywords: | Anti-HSET, Anti-KIFC1, Anti-Kinesin-like protein 2, Anti-Kinesin-like protein KIFC1, Anti-Kinesin-related protein HSET |
| Application: | WB, IP, IHC |
| Host: | Rabbit |
| Species reactivity: | human |
From 165.00€
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Item number: IHC-00496
Protein function: Minus end-directed microtubule-dependent motor required for bipolar spindle formation (PubMed:15843429). May contribute to movement of early endocytic vesicles. Regulates cilium formation and structure. [The UniProt Consortium]
| Keywords: | Anti-HSET, Anti-KIFC1, Anti-Kinesin-like protein 2, Anti-Kinesin-like protein KIFC1, Anti-Kinesin-related protein HSET |
| Application: | IHC |
| Host: | Rabbit |
| Species reactivity: | human |
From 165.00€
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Item number: Cay21898-1
AZ82 is a small molecule inhibitor of KIFC1/HSET, a kinesin-14 family protein that is important for assembling bipolar spindles in cancer cells containing supernumerary centrosomes. AZ82 binds to the KIFC1/microtubule complex and inhibits its microtubule-stimulated activity (IC50 = 300 nM) in an ATP-competitive (Ki...
| Keywords: | alphaR-[[(5-methyl-4-propyl-2-thienyl)carbonyl]amino]-N-(3R)-3-pyrrolidinyl-6-[3-(trifluoromethoxy)phenyl]-3-pyridinepropa... |
| Application: | KIFC1 inhibitor |
| CAS | 1449578-65-7 |
| MW: | 560.6 D |
From 59.00€
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Item number: Cay22936-1
CW069 is an allosteric inhibitor of KIFC/HSET (IC50 = 75 µM), a microtubule motor protein involved in bipolar spindle assembly and centrosome clustering. It increases the number of multipolar spindles in N1E-115 mouse neuroblastoma cells with supernumerary centrosomes when used at concentrations of 100 and 200 µM,...
| Keywords: | 5-iodo-2-[[(2S)-1-oxo-3-phenyl-2-[(phenylmethyl)amino]propyl]amino]-benzoic acid |
| Application: | Allosteric HSET inhibitor |
| CAS | 1594094-64-0 |
| MW: | 500.3 D |
From 89.00€
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Item number: ATA-HPA062674.100
Protein function: Minus end-directed microtubule-dependent motor required for bipolar spindle formation (PubMed:15843429). May contribute to movement of early endocytic vesicles. Regulates cilium formation and structure. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as...
| Keywords: | Anti-HSET, Anti-KIFC1, Anti-Kinesin-like protein 2, Anti-Kinesin-like protein KIFC1, Anti-Kinesin-related protein HSET |
| Application: | IHC |
| Host: | Rabbit |
| Species reactivity: | human |
From 369.00€
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Item number: ATA-HPA055997.100
Protein function: Minus end-directed microtubule-dependent motor required for bipolar spindle formation (PubMed:15843429). May contribute to movement of early endocytic vesicles. Regulates cilium formation and structure. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as...
| Keywords: | Anti-HSET, Anti-KIFC1, Anti-Kinesin-like protein 2, Anti-Kinesin-like protein KIFC1, Anti-Kinesin-related protein HSET |
| Application: | ICC, IHC |
| Host: | Rabbit |
| Species reactivity: | human |
From 246.00€
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Item number: NSJ-RQ6649
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Kinesin-like protein KIFC1 is a protein that in humans is encoded by the KIFC1 gene. Kinesin superfamily proteins (KIFs) are molecular motors that drive directional, microtubule-dependent intracellular transport of membrane-bound organelles and other...
| Keywords: | Anti-HSET, Anti-KIFC1, Anti-Kinesin-like protein 2, Anti-Kinesin-like protein KIFC1, Anti-Kinesin-related protein HSET,... |
| Application: | WB, IHC (paraffin), IF, FC, Direct ELISA |
| Host: | Rabbit |
| Species reactivity: | human, mouse, rat |
790.00€
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Item number: CSB-EP871587HU.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 1-673aa. Protein Length: Full Length. Tag Info: N-terminal 10xHis-tagged and C-terminal Myc-tagged. Target Protein Sequence: MDPQRSPLLE VKGNIELKRP LIKAPSQLPL SGSRLKRRPD QMEDGLEPEK KRTRGLGATT KITTSHPRVP SLTTVPQTQG QTTAQKVSKK TGPRCSTAIA TGLKNQKPVP...
| Keywords: | HSET, KIFC1, Kinesin-like protein 2, Kinesin-like protein KIFC1, Kinesin-related protein HSET, Recombinant Human... |
| Application: | Activity not tested |
| Expressed in: | E.coli |
| Origin: | human |
| MW: | 81.2 kD |
From 292.00€
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Item number: TGM-T6209-100mg
Description: CW-069 (IC50=75 µM), an allosteric selective inhibitor of microtubule motor protein HSET, exhibits remarkable specificity over KSP. Target: Kinesin, Microtubule Associated. Smiles: OC(=O)c1cc(I)ccc1NC(=O)[C@H](Cc1ccccc1)NCc1ccccc1. References: Watts CA, et al. Chem Biol. 2013, 20(11), 1399-1410.
| Keywords: | CW069 |
| Application: | Allosteric HSET inhibitor |
| CAS | 1594094-64-0 |
| MW: | 500.33 D |
From 35.00€
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NEW
Item number: E-AB-67573.120
KIFC1 (Kinesin Family Member C1) is a Protein Coding gene. Among its related pathways are Response to elevated platelet cytosolic Ca2+ and Golgi-to-ER retrograde transport. Gene Ontology (GO) annotations related to this gene include ATPase activity and microtubule motor activity. An important paralog of this gene is...
| Keywords: | Anti-HSET, Anti-KIFC1, Anti-Kinesin-like protein 2, Anti-Kinesin-like protein KIFC1, Anti-Kinesin-related protein HSET,... |
| Application: | IHC, IF |
| Host: | Rabbit |
| Species reactivity: | human, mouse, rat |
From 243.00€
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Item number: G-AGMB00312.100
KIFC1 Monoclonal Antibody from Assay Genie is a high quality antibody for research use only. Protein Function: Minus end-directed microtubule-dependent motor required for bipolar spindle formation (PubMed:15843429). May contribute to movement of early endocytic vesicles (By similarity). Regulates cilium formation...
| Keywords: | Anti-KIFC1, Anti-Kinesin-like protein 2, Anti-Kinesin-like protein KIFC1, Anti-Kinesin-related protein HSET |
| Application: | WB, IHC-F, IHC-P, ICC/IF, FC, IP |
| Host: | Rabbit |
| Species reactivity: | human |
From 134.00€
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