76 products were found matching "K10398"!
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Anti-KIF11
Item number: ABS-KC-6062.100
Protein function: Motor protein required for establishing a bipolar spindle during mitosis (PubMed:19001501). Required in non-mitotic cells for transport of secretory proteins from the Golgi complex to the cell surface (PubMed:23857769). [The UniProt Consortium]
| Keywords: | Anti-Kinesin-like protein KIF11, Anti-Kinesin-like protein 1, Anti-Kinesin-like spindle protein HKSP, Anti-Kinesin-related... |
| Host: | Mouse |
| Species reactivity: | human |
From 232.00€
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(S)-Monastrol
Item number: TGM-T4649-10mg
Description: Monastrol is a potent and cell-permeable inhibitor of the mitotic kinesin Eg5. Target: Kinesin. Smiles: CCOC(=O)C1=C(C)NC(=S)NC1c1cccc(O)c1. References: Cochran JC, et al. Monastrol inhibition of the mitotic kinesin Eg5. J BiolChem. 2005 Apr 1,280(13):12658-67.
| Application: | Eg5 inhibitor |
| CAS | 254753-54-3 |
| MW: | 292.35 D |
594.00€
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Monastrol
Item number: TGM-T4048-100mg
Description: Monastrol ((±)-Monastrol) is a potent and cell-permeable inhibitor of the mitotic kinesin Eg5. Target: Kinesin, Apoptosis. Smiles: CCOC(=O)C1=C(C)NC(=S)NC1c1cccc(O)c1. References: Cochran JC, et al. Monastrol inhibition of the mitotic kinesin Eg5. J BiolChem. 2005 Apr 1,280(13):12658-67.
| Keywords: | (±)-Monastrol |
| Application: | Kinesin-like protein KIF11 / Eg5 inhibitor |
| CAS | 329689-23-8 |
| MW: | 292.35 D |
From 42.00€
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EMD534085
Item number: TGM-TQ0314-10mg
Description: EMD534085 is an effective and selective mitotic kinesin-5 inhibitor (IC50: 8 nM). Target: Kinesin. Smiles: [H][C@@]12CC[C@H](CNC(=O)NCCN(C)C)O[C@]1([H])c1cc(ccc1N[C@H]2c1ccccc1)C(F)(F)F. References: Schiemann K, et al. The discovery and optimization of hexahydro-2H-pyrano[3,2-c]quinolines (HHPQs) as...
| Application: | Eg5 inhibitor |
| CAS | 858668-07-2 |
| MW: | 476.53 D |
From 98.00€
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ARQ 621
Item number: TGM-T6393-100mg
Description: ARQ 621 is an allosteric, and selective Eg5 mitotic motor protein inhibitor. Phase 1. Target: Kinesin. Smiles: NCCCN([C@H](CC#C)c1nc2cc(Cl)ccc2c(=O)n1Nc1ccccc1)C(=O)c1cccc(Cl)c1F. References: Rosen L, et al. Annual Meeting of ASCO: abstract 3076
| Application: | Eg5 inhibitor |
| CAS | 1095253-39-6 |
| MW: | 552.43 D |
From 57.00€
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Eg5 Inhibitor V, trans-24
Item number: TGM-T11155-100mg
Description: Eg5 Inhibitor V, trans-24, is a specific and potent Eg5 inhibitor with an IC50 value of 0.65 µM, suitable for use in cancer research. Target: Kinesin. Smiles: [H][C@@]12Cc3c([nH]c4ccccc34)[C@H](N1C(=O)N(Cc1ccccc1)C2=O)c1cccc(O)c1. References: Sunder-Plassmann N, et al. Synthesis and biological...
| Application: | Eg5 (kinesin family member 11ABCG2, KIF11) inhibitor |
| CAS | 869304-55-2 |
| MW: | 423.46 D |
From 93.00€
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Litronesib
Item number: TGM-T11859L-100mg
Description: Litronesib is a selective inhibitor of mitosis-specific kinesin Eg5. It also has antitumor activity. Target: Kinesin. Smiles: CCNCCS(=O)(=O)NC[C@]1(SC(NC(=O)C(C)(C)C)=NN1C(=O)C(C)(C)C)c1ccccc1. References: Ye XS, et al. A Novel Eg5 Inhibitor (LY2523355) Causes Mitotic Arrest and Apoptosis in Cancer...
| Keywords: | KF-89617, LY-2523355 |
| Application: | Targets kinesin family member 11 (KIF11, EG5) |
| CAS | 910634-41-2 |
| MW: | 511.7 D |
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Ispinesib
Item number: TGM-T2103-1mg
Description: Ispinesib (SB-715992), a selective, effectvie and reversible inhibitor of kinesin spindle protein (KSP), is derived from quinazolinone, with antineoplastic properties. Target: Apoptosis, KSP, Kinesin. Smiles: CC(C)[C@@H](N(CCCN)C(=O)c1ccc(C)cc1)c1nc2cc(Cl)ccc2c(=O)n1Cc1ccccc1. References: Lad L, et...
| Keywords: | CK0238273, SB-715992 |
| Application: | Kinesin spindle protein (KSP/EG5 KIF11) inhibitor |
| CAS | 336113-53-2 |
| MW: | 517.06 D |
From 34.00€
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K858 (Racemic)
Item number: TGM-T3120-100mg
Description: K858 Racemic (K858) is a selective mitotic kinesin Eg5 inhibitor which acts in an ATP-noncompetitive manner. Target: Apoptosis, Kinesin. Smiles: CC(=O)NC1=NN(C(C)=O)C(C)(S1)c1ccccc1. References: Nakai R, et al. Y Res. 2009 May 1,69(9):3901-9.
| Keywords: | K858, K858 Racemic |
| Application: | KIF11 inhibitor |
| CAS | 72926-24-0 |
| MW: | 277.34 D |
From 40.00€
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Dimethylenastron
Item number: TGM-T3118-100mg
Description: Dimethylenastron, an Eg5 inhibitor, arrests cells with monopolar spindles to which all chromosomes attach in a syntelic manner. Target: Kinesin. Smiles: O=C1C=2C(NC(=S)NC2CC(C)(C)C1)C3=CC(O)=CC=C3. References: Aljaberi AM, et al. Cell Cycle. 2015,14(11):1738-47.
| Application: | KIF11 EG5 inhibitor |
| CAS | 863774-58-7 |
| MW: | 302.39 D |
From 31.00€
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S-trityl-L-Cysteine
Item number: TGM-T36816-100mg
Description: S-trityl-L-Cysteine is a potent inhibitor of human mitotic kinesin Eg5. Target: Kinesin. Smiles: C(SC[C@@H](C(O)=O)N)(C1=CC=CC=C1)(C2=CC=CC=C2)C3=CC=CC=C3. References: Wu W, et al. S-trityl-L-cysteine, a novel Eg5 inhibitor, is a potent chemotherapeutic strategy in neuroblastoma. Oncol Lett. 2018...
| Keywords: | STLC |
| Application: | Kif11 inhibitor |
| CAS | 2799-07-7 |
| MW: | 363.47 D |
From 31.00€
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Anti-KIF11
Item number: CSB-PA002261.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Keywords: | Anti-EG5, Anti-KIF11, Anti-TRIP-5, Anti-Kinesin-like protein 1, Anti-TR-interacting protein 5, Anti-Kinesin-like protein... |
| Application: | ELISA, WB, IHC, IF |
| Host: | Rabbit |
| Species reactivity: | human |
From 126.00€
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