94 products were found matching "K09414"!

Heat-shock factor 1 (Hsf1) is a transcription factor involved in the heat-shock response. It is composed of an N-terminal DNA-binding domain, a hydrophobic repeat region (HR-A/B), which mediates oligomerization required for DNA binding, a D domain, a regulatory domain, a repeat region (HR-C), which prevents...

DTHIB is an inhibitor of heat shock factor 1 (Hsf1). It binds to the DNA-binding domain of Hsf1 (Kd = 160 nM) and inhibits heat-induced increases in the Hsf1 target proteins heat shock protein 27 (Hsp27) and Hsp70 levels in mouse embryonic fibroblasts (MEFs) when used at a concentration of 10 µM. It decreases...

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human HSF1. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human HSF1. Next,...

The HSE (Heat Shock Response) Luciferase Reporter Lentiviruses are replication incompetent, HIV-based, VSV-G pseudotyped lentiviral particles ready to transduce most mammalian cells, including primary and non-dividing cells. These viruses transduce cells with the firefly luciferase gene driven by multiple copies of...

0.5mg/ml if reconstituted with 0.2ml sterile DI water. HSF1 (HEAT-SHOCK TRANSCRIPTION FACTOR 1), also called HEAT-SHOCK FACTOR 1, is a protein that in humans is encoded by the HSF1 gene. The product of HSF1 gene is a heat-shock transcription factor. The International Radiation Hybrid Mapping Consortium maps the HSF1...

KRIBB11 is an inhibitor of heat shock factor 1 (Hsf1) with an IC50 value of 1.2 µM in a luciferase reporter assay. It blocks heat shock-induced Hsp70, Hsp40, and Hsp27 mRNA expression and down-regulates protein expression of the Hsf1 target proteins Hsp70 and Hsp27 in HCT116 cells in a dose-dependent manner. KRIBB11...

Protein function: Function as a stress-inducible and DNA-binding transcription factor that plays a central role in the transcriptional activation of the heat shock response (HSR), leading to the expression of a large class of molecular chaperones heat shock proteins (HSPs) that protect cells from cellular insults'...

The product of this gene is a heat-shock transcription factor. Transcription of heat-shock genes is rapidly induced after temperature stress. Hsp90, by itself and/or associated witHuman, Mouseultichaperone complexes, is a major repressor of this gene. Protein function: Function as a stress-inducible and DNA-binding...

Protein function: DNA-binding protein that specifically binds heat shock promoter elements (HSE) and activates transcription. In higher eukaryotes, HSF is unable to bind to the HSE unless the cells are heat shocked. [The UniProt Consortium]

Protein function: DNA-binding protein that specifically binds heat shock promoter elements (HSE) and activates transcription. In higher eukaryotes, HSF is unable to bind to the HSE unless the cells are heat shocked. [The UniProt Consortium]

Protein function: DNA-binding protein that specifically binds heat shock promoter elements (HSE) and activates transcription. In higher eukaryotes, HSF is unable to bind to the HSE unless the cells are heat shocked. [The UniProt Consortium]

Protein function: Function as a stress-inducible and DNA-binding transcription factor that plays a central role in the transcriptional activation of the heat shock response (HSR), leading to the expression of a large class of molecular chaperones heat shock proteins (HSPs) that protect cells from cellular insults'...