51 products were found matching "K09095"!

Belzutifan is an inhibitor of hypoxia-inducible factor-2alpha (HIF-2alpha). It inhibits HIF-2alpha heterodimerization with the aryl hydrocarbon receptor nuclear translocator (ARNT) PAS-B domain in a cell-free assay (Ki = 23 nM), activation of HIF-2alpha in a reporter assay using 786-O renal cell carcinoma cells...

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse HIF2a. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse HIF2a. Next,...

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human HIF2a. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human HIF2a. Next,...

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat HIF2a. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat HIF2a. Next,...

Protein function: Transcription factor involved in the induction of oxygen regulated genes. Binds to core DNA sequence 5'-[AG]CGTG-3' within the hypoxia response element (HRE) of target gene promoters. Regulates the vascular endothelial growth factor (VEGF) expression and seems to be implicated in the development of...

HIF-2alpha antagonist 2 is an inhibitor of hypoxia-inducible factor-2alpha (HIF-2alpha) PAS-B domain heterodimerization. It binds to the HIF-2alpha PAS-B domain (Kd = 81 nM) to inhibit heterodimerization with the aryl hydrocarbon receptor nuclear translocator (ARNT) PAS-B domain in cell-free assays when used at...

Anti-HO-1 Antibody was purified by Protein G chromatography. A BLAST analysis was used to suggest cross-reactivity with HO-1 from Human, Mouse, Bovine, Canine, Guinea pig, Hamster, Monkey, Pig, Rabbit, and Rat based on 100% homology with the immunizing sequence. Does not cross-react with HO-2. Cross-reactivity with...

Anti-HIF2? Antibody was purified by Protein G chromatography. This monoclonal antibody is specific for human HIF2? protein. A BLAST analysis was used to suggest cross-reactivity with HIF2? from human based on 100% homology with the immunizing sequence. Cross-reactivity with HIF2? from other sources has not been...

0.5mg/ml if reconstituted with 0.2ml sterile DI water. HIF-2 alpha is also designated EPAS1 whose gene is mapped to 2p21-p16. The predicted mouse protein is 88% identical to human. The human gene contains 15 exons and spans at least 120 kb. The positions of the introns within the genomic region encoding the...

The kit is a Sandwich enzyme immunoassay for in vitro quantitative measurement of HIF-2alpha in serum, plasma and other biological fluids. Detection Range: 0.16--10ng/mL. Sensitivity: 0.1ng/mL. Protein function: Transcription factor involved in the induction of oxygen regulated genes. Binds to core DNA sequence...

Transcription factor involved in the induction of oxygen regulated genes. Binds to core DNA sequence 5'-[AG]CGTG-3' within the hypoxia response element (HRE) of target gene promoters. Regulates the vascular endothelial growth factor (VEGF) expression and seems to be implicated in the development of blood vessels and...